Drug & supplement interaction

Ornithine Ketoglutarate (okg) + Succinylcholine

Succinylcholine brand names: Anectine, Quelicin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Ornithine Ketoglutarate (okg) and Succinylcholine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ornithine Ketoglutarate (okg) and Succinylcholine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Succinylcholine and Ornithine Ketoglutarate (okg) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ornithine Ketoglutarate (okg) at all — not against Succinylcholine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ornithine Ketoglutarate (okg) safety at a glance

Ornithine Ketoglut... overall Use caution Generally well tolerated in short-term clinical studies, but long-term safety as a daily supplement is not well established.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Succinylcholine and Ornithine Ketoglutarate (okg)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ornithine Ketoglutarate (okg) Itself Has Been Linked To

This is not an interaction — nothing below involves Succinylcholine. It is the side-effect record for Ornithine Ketoglutarate (okg) on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Ornithine Ketoglutarate (okg), this list is the first place to look.

  • Bloating or gas / Stomach pain / Diarrhea / Vomiting / Nausea Additional detail

    “Orally, the most common adverse effects are gastrointestinal in nature, including abdominal pain, bloating, diarrhea, nausea, and vomiting.”

    Ornithine Ketoglutarate (okg) · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 67449. Karsegard, V. L., Raguso, C. A., Genton, L., Hirschel, B., and Pichard, C. L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. Nutrition 2004;20(6):515-520.
    2. 67453. Meaume, S., Kerihuel, J. C., Constans, T., Teot, L., Lerebours, E., Kern, J., and Bourdel, Marchasson, I. Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. J.Nutr.H PubMed
    3. 67466. Brocker, P., Vellas, B., Albarede, J. L., and Poynard, T. A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects. Age Ageing 1994;23(4):303-306. PubMed
  • Itching Additional detail

    “Orally, pruritus has occurred rarely.”

    Ornithine Ketoglutarate (okg) · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 67466. Brocker, P., Vellas, B., Albarede, J. L., and Poynard, T. A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects. Age Ageing 1994;23(4):303-306. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Ornithine Ketoglutarate (okg) — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Succinylcholine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Succinylcholine column appears here.

Everything else you take

See Every Supplement That Interacts With Succinylcholine

This page covers Ornithine Ketoglutarate (okg) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Succinylcholine page lists 25 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Procaine (major), Bacopa (moderate), Bael (moderate), Betel Nut (moderate) and Boxwood (moderate).

By severity: 1 major · 23 moderate · 1 minor.

From our pharmacist’s overview on the Succinylcholine page

“Succinylcholine (Anectine, Quelicin) is the fast-acting paralytic that anesthesia teams use to relax muscles for intubation and surgery, and its interaction list deserves genuine respect. Of the 25 entries on file, 21 are herbs and supplements that raise acetylcholine, the same nerve-signaling chemical this drug works through, so they…”

Reviewed by 2 · Jul 18, 2026

Open the Succinylcholine interaction page

How much people look this up

Where Ornithine Ketoglutarate (okg) and Succinylcholine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ornithine Ketoglutarate (okg)
Steady interest

#1,360 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Succinylcholine
Top 10%

#162 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ornithine Ketoglutarate (okg) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Ornithine Ketoglutarate (okg) and Succinylcholine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ornithine Ketoglutarate (okg)

What is Ornithine Ketoglutarate (okg)?

  • Wound healing and recovery from injury
  • Muscle preservation in older or hospitalized adults
  • Sports and athletic performance
  • Recovery from burns or surgery
  • Support during malnutrition or critical illness

Ornithine ketoglutarate (OKG) is a compound made by combining the amino acids ornithine and alpha-ketoglutarate, and it has mainly been studied in hospital settings for wound healing, burns, and malnutrition. Evidence for everyday use, such as sports performance, is limited and not convincing. Talk to your pharmacist or doctor before using it, especially if you have a health condition.

Not applicable (a synthesized amino acid salt) · Powder, capsules, tablets, and as part of clinical nutrition formulas

An interaction check asks whether these two react with each other — it does not ask whether Ornithine Ketoglutarate (okg) is a good idea for someone in your situation. Here is what our Ornithine Ketoglutarate (okg) record says about it on its own.

Ornithine Ketoglutarate (okg): dosing

There is no official standardized dose of OKG for general use. In clinical studies, doses were chosen by researchers and given to specific patient groups, often under medical care.If you use a supplement, follow the directions on the product label and do not assume more is better.

From our Ornithine Ketoglutarate (okg) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ornithine Ketoglutarate (okg) monograph & all interactions
Medication

About Succinylcholine

Most-Reported Side Effects for Succinylcholine

From FAERS, the FDA’s public side-effect reporting system (3,844 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hypotension 310 reports
Hyperthermia malignant 287 reports
Cardiac arrest 260 reports
Anaphylactic shock 220 reports
Anaphylactic reaction 184 reports
Keep checking

Other Drugs & Ornithine Ketoglutarate (okg)

Browse every other medication we’ve checked against Ornithine Ketoglutarate (okg) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Ornithine Ketoglutarate (okg) References

The 3 references that drive our Ornithine Ketoglutarate (okg) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Karsegard, V. L., Raguso, C. A., Genton, L., Hirschel, B., and Pichard, C. L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. Nutrition 2004;20(6):515-520.
  2. Meaume, S., Kerihuel, J. C., Constans, T., Teot, L., Lerebours, E., Kern, J., and Bourdel, Marchasson, I. Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. J.Nutr.H PubMed
  3. Brocker, P., Vellas, B., Albarede, J. L., and Poynard, T. A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects. Age Ageing 1994;23(4):303-306. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ornithine Ketoglutarate (okg) and Succinylcholine Together: Common Questions

Is it safe to take Ornithine Ketoglutarate (okg) with Succinylcholine?
We do not list a known interaction between Ornithine Ketoglutarate (okg) and Succinylcholine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Succinylcholine interact with any supplements?
Yes. Succinylcholine has documented interactions with 25 supplements in our database — Ornithine Ketoglutarate (okg) is not one of them. The Succinylcholine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Succinylcholine and Ornithine Ketoglutarate (okg)?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.