Medication interaction hub

What Supplements Interact with Succinylcholine?

Succinylcholine brand names: Anectine, Quelicin. Every interaction below applies to the brands too.

25 Interactions 1 Major 23 Moderate 1 Minor
Curated & coded by · Clinical Pharmacist · Updated September 24, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Succinylcholine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Succinylcholine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Succinylcholine (Anectine, Quelicin) is the fast-acting paralytic that anesthesia teams use to relax muscles for intubation and surgery, and its interaction list deserves genuine respect. Of the 25 entries on file, 21 are herbs and supplements that raise acetylcholine, the same nerve-signaling chemical this drug works through, so they could theoretically add cholinergic side effects. A smaller group, including magnesium and even ordinary potatoes eaten before preoperative fasting, has been shown to prolong the paralysis itself and slow recovery from anesthesia. The one major-rated entry is procaine, and intravenous procaine is flatly contraindicated with this drug.

Since you will never dose succinylcholine yourself, the useful move is disclosure. Tell your anesthesia team about every supplement and herb you use, and stop whatever they advise before the procedure. The remaining 23 entries are moderate and one is minor, but a paralytic that lingers past its welcome is nobody's idea of minor.

— , Clinical Pharmacist · July 18, 2026

Major 1 Moderate 23 Minor 1 No known interaction 1,427

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Succinylcholine: Top Interactions at a Glance

The most significant Succinylcholine supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 25 interacting ingredients — plus 1,427 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Succinylcholine + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Procaine + Succinylcholinei

Intravenous use of procaine hydrochloride is contraindicated.

Read the full interaction
The complete list

Every Supplement Checked Against Succinylcholine

All 1,452 ingredients in our database, ranked by severity — 25 with a Succinylcholine interaction on file and 1,427 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Succinylcholine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Syrian Rue with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might increase the effects and adverse effects of cholinergic drugs.

Full Syrian Rue + Succinylcholine answer

Can you take Teazle with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that teazle extract can inhibit acetylcholinesterase activity.

Full Teazle + Succinylcholine answer

Can you take Thyme with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of cholinergic drugs and thyme essential oil might cause additive cholinergic effects.

Full Thyme + Succinylcholine answer

Can you take Toothed Clubmoss with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Huperzine A, a constituent of toothed clubmoss, has demonstrated acetylcholinesterase inhibitory properties.

Full Toothed Clubmoss + Succinylcholine answer

Can you take Deanol with Succinylcholine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.

Full Deanol + Succinylcholine answer

Can you take Procaine with Succinylcholine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Intravenous use of procaine hydrochloride is contraindicated.

Full Procaine + Succinylcholine answer

Can you take Betel Nut with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro and animal research suggests that betel nut extract can inhibit acetylcholinesterase activity.

Full Betel Nut + Succinylcholine answer

Can you take Lithium with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lithium supplements with skeletal muscle relaxants might prolong neuromuscular blockade.

Full Lithium + Succinylcholine answer

Can you take Magnesium with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect...

Full Magnesium + Succinylcholine answer

Can you take Potato with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In humans, consuming potatoes prior to preoperative fasting prolongs the duration of the succinylcholine-induced neuromuscular block and slo...

Full Potato + Succinylcholine answer

Can you take Bacopa with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.

Full Bacopa + Succinylcholine answer

Can you take Bael with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bael leaf extract shows acetylcholinesterase (AChE) inhibitory activity in vitro.

Full Bael + Succinylcholine answer

Can you take Boxwood with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that boxwood extract can inhibit acetylcholinesterase activity.

Full Boxwood + Succinylcholine answer

Can you take Calamus with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of cholinergic drugs and calamus might have an additive effect and increase the risk of cholinergic effects.

Full Calamus + Succinylcholine answer

Can you take Clubmoss with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity.

Full Clubmoss + Succinylcholine answer

Can you take Dimethylsulfoxide (dmso) with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, DMSO might increase the risk of cholinergic adverse effects when taken with cholinergic drugs.

Full Dimethylsulfoxide (dmso) + Succinylcholine answer

Can you take European Barberry with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.

Full European Barberry + Succinylcholine answer

Can you take Huperzine A with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of huperzine A with cholinergic drugs might increase the effects and side effects of these medications.

Full Huperzine A + Succinylcholine answer

Can you take Iboga with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, iboga might have additive effects with cholinergic drugs.

Full Iboga + Succinylcholine answer

Can you take Marjoram with Succinylcholine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Full Marjoram + Succinylcholine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Succinylcholine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Succinylcholine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Succinylcholine sits in 3 interaction categories. Open any one to see what the group means:

Cholinergic Drugs 21 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

21 of the supplement ingredients on this page reach Succinylcholine through this category.

Skeletal Muscle Relaxants 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Succinylcholine through this category.

Succinylcholine 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Succinylcholine through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Succinylcholine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Succinylcholine.

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Pharmacist Counseling Corner

Succinylcholine & Supplements: Common Questions

What supplements interact with Succinylcholine?
In our interaction database, 25 supplement and herbal ingredients have an interaction with Succinylcholine on file — 1 rated major, 23 moderate, and 1 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Procaine, Betel Nut, Lithium.
Which Succinylcholine supplement interactions are the most serious?
The 1 major-rated combination — led by Procaine — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Succinylcholine?
That depends entirely on which supplement. The honest answer for Succinylcholine is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Anectine have the same supplement interactions as Succinylcholine?
Yes — Anectine, Quelicin all contain Succinylcholine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Succinylcholine and my other medications?
This page covers Succinylcholine against supplements and herbal ingredients. Checking Succinylcholine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.