Drug & supplement interaction

Pao Pereira + Ribavirin

Ribavirin brand names: Rebetol, Copegus, Ribasphere, Moderiba.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Pao Pereira and Ribavirin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ribavirin states a food rule worth keeping to.

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Interaction report

Pao Pereira and Ribavirin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ribavirin and Pao Pereira in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pao Pereira at all — not against Ribavirin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pao Pereira safety at a glance

Pao Pereira overall Use caution Human safety data are limited, so use with care and professional guidance.
Pregnancy Avoid Not enough safety data; avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ribavirin and Pao Pereira? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ribavirin’s Own FDA Label Lists

This is not an interaction — none of it involves Pao Pereira. These are the most notable effects listed in the ADVERSE REACTIONS section of Ribavirin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • Anemia Worth acting on mentioned in 13.1% of FDA reports for Ribavirin
  • Thoughts of self-harm Worth acting on
  • Pancreatitis Worth acting on
  • Chest pain Worth acting on
  • Low mood Worth acting on
  • A low platelet count Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 41 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ribavirin. Read the label on DailyMed › Where a percentage is shown, it is the share of 63,877 voluntary FDA FAERS reports for Ribavirin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Pao Pereira’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pao Pereira side to compare — that is a limit of the record, not a statement that Pao Pereira has no side effects.

How to take them

Some Ribavirin Products Have a Food Rule — Pao Pereira Should Not Break It

At least one FDA label for a product containing Ribavirin says to take it with food. If you take Pao Pereira on an empty stomach out of habit, keep them separate — and take Ribavirin with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ribavirin products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Ribavirin capsules should be taken with food [see Clinical Pharmacology (12.3) ].

From the Dosage and Administration section of the FDA label we read for Ribavirin — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Ribavirin

This page covers Pao Pereira only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ribavirin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Ribavirin page

“Nearly every entry on this ribavirin page pulls the same lever, changing how much of the drug reaches your bloodstream, and that deserves genuine care here. Ribavirin (Rebetol, Copegus) is an antiviral for hepatitis C, and treatment succeeds only when levels stay steady enough to keep the virus in check, so anything that quietly lowers…”

Reviewed by 2 · Jul 18, 2026

Open the Ribavirin interaction page

One more smart check

Taking Pao Pereira as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Pao Pereira, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pao Pereira. Even though Pao Pereira itself has no known interaction with Ribavirin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pao Pereira and Ribavirin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pao Pereira
Steady interest

#1,041 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ribavirin
Top 25%

#602 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Pao Pereira is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pao Pereira reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Pao Pereira and Ribavirin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pao Pereira

What is Pao Pereira?

  • Immune support
  • Cancer support (complementary use)
  • Antimalarial/fever (traditional)
  • Digestive complaints (traditional)
  • General tonic

Pao Pereira is a bark extract from a South American tree that is marketed mainly as a complementary cancer and immune-support supplement. Human evidence is very limited, and most research comes from laboratory and animal studies, so it should not be used in place of proven medical care. Talk with your pharmacist or doctor before trying it, especially if you have a serious health condition.

Geissospermum laeve · Apocynaceae · Bark (and bark extract) · Capsules, tinctures, liquid extracts, powdered bark

An interaction check asks whether these two react with each other — it does not ask whether Pao Pereira is a good idea for someone in your situation. Here is what our Pao Pereira record says about it on its own.

Pao Pereira: dosing

There is no established or standardized dose for Pao Pereira. Different products contain different amounts and strengths of bark extract.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our Pao Pereira monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pao Pereira monograph & all interactions
Medication

About Ribavirin

What Is Ribavirin Used For?

Brand names: Rebetol, Copegus, Ribasphere, Moderiba

Ribavirin comes in different forms for different uses. Ribavirin capsules are used in combination with interferon alfa-2b (pegylated or non-pegylated) to treat chronic hepatitis C (CHC) in patients 3 years and older with compensated liver disease. Ribavirin tablets are used in combination with PEGASYS® (peginterferon alfa-2a) to treat chronic hepatitis C in patients 5 years and older with compensated liver disease who have not previously been treated with interferon — including adults who also have HIV. Ribavirin for inhalation solution is a separate product used to treat hospitalized infants and young children with severe lower respiratory tract infections caused by respiratory syncytial virus (RSV).

Ribavirin must never be used alone to treat hepatitis C — it only works as part of combination therapy. Only the most severe RSV infections requiring hospitalization should be treated with the inhaled form; mild RSV illness in children does not require this treatment.

See full Ribavirin drug information
Keep checking

Other Drugs & Pao Pereira

Browse every other medication we’ve checked against Pao Pereira — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Pao Pereira against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pao Pereira list.

See the full Pao Pereira interactions page
See every supplement checked against Ribavirin, ranked by severity
Evidence & sources

Pao Pereira References

The 4 sources that drive our Pao Pereira monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Pao Pereira is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  4. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pao Pereira and Ribavirin Together: Common Questions

Is it safe to take Pao Pereira with Ribavirin?
We do not list a known interaction between Pao Pereira and Ribavirin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Pao Pereira and Ribavirin at the same time of day?
At least one FDA label for a product containing Ribavirin says to take it with food. If you take Pao Pereira on an empty stomach out of habit, keep them separate and take Ribavirin with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Ribavirin products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Ribavirin interact with any supplements?
Yes. Ribavirin has documented interactions with 17 supplements in our database — Pao Pereira is not one of them. The Ribavirin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pao Pereira monograph Uses, safety profile, and every drug interaction in one place Ribavirin drug information The full plain-English guide to this medication Ribavirin supplement interactions Every supplement checked against Ribavirin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ribavirin and Pao Pereira?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.