Partridgeberry + Upadacitinib Hemihydrate
Upadacitinib Hemihydrate brand name: Rinvoq.
We found no known interaction between Partridgeberry and Upadacitinib Hemihydrate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Partridgeberry and Upadacitinib Hemihydrate
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Upadacitinib Hemihydrate and Partridgeberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Partridgeberry at all — not against Upadacitinib Hemihydrate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Partridgeberry safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Upadacitinib Hemihydrate
This page covers Partridgeberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Upadacitinib Hemihydrate page lists 138 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 94 moderate · 41 minor.
From our pharmacist’s overview on the Upadacitinib Hemihydrate page
“Grapefruit is the pairing I would want anyone on Rinvoq (upadacitinib) to know about first. The drug is cleared by a liver enzyme called CYP3A4, and grapefruit blocks that enzyme, letting blood levels climb, which matters for a medicine that already dials down the immune system.”
Reviewed by 2 · Jul 18, 2026
Where Partridgeberry and Upadacitinib Hemihydrate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,094 of 1,452 supplements looked up here in the last 7 days
#569 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Partridgeberry is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Partridgeberry reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Partridgeberry and Upadacitinib Hemihydrate records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Partridgeberry
What is Partridgeberry?
- Toning the uterus in late pregnancy (traditional)
- Menstrual cramps and painful periods
- Supporting childbirth and labor (traditional)
- Urinary and bladder discomfort
- Digestive complaints
Partridgeberry (Mitchella repens) is a traditional North American herb most often used as a so-called 'uterine tonic' near the end of pregnancy and for menstrual discomfort. There is very little modern scientific research to confirm any of these uses, and because it has traditionally been used to affect the uterus, it should not be used during pregnancy without medical guidance. Talk to your pharmacist or doctor before trying it.
Mitchella repens · Rubiaceae · Leaves and aerial parts (whole herb), sometimes berries · Tea, tincture, capsules, dried herb
An interaction check asks whether these two react with each other — it does not ask whether Partridgeberry is a good idea for someone in your situation. Here is what our Partridgeberry record says about it on its own.
Partridgeberry: dosing
There is no established, scientifically supported dose for partridgeberry. Traditional preparations were made as teas or tinctures, but standardized dosing based on modern research does not exist.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount. When in doubt, use the lowest amount suggested and consult a healthcare professional.
From our Partridgeberry monograph — the full record covers uses, side effects and every documented interaction.
About Upadacitinib
What Is Upadacitinib Used For?
Brand name: Rinvoq
Upadacitinib is approved for adults and some children with moderate-to-severe inflammatory conditions when other treatments haven't worked well enough. It targets overactive immune signaling that drives these diseases.
Conditions it treats include:
- Rheumatoid arthritis (RA) — in adults who didn't respond to TNF blocker medications
- Psoriatic arthritis — in adults and children 2 years and older who didn't respond to TNF blockers
- Atopic dermatitis (eczema) — in people 12 and older whose disease isn't controlled by other systemic therapies
- Ulcerative colitis — in adults who didn't respond to TNF blockers or other approved therapies
- Crohn's disease — in adults who didn't respond to TNF blockers or other approved therapies
Other Drugs & Partridgeberry
Browse every other medication we’ve checked against Partridgeberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Partridgeberry against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Sertraline ›
- Testosterone ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Methamphetamine ›
- Tirzepatide ›
- Ibuprofen ›
- Docusate ›
- Warfarin Sodium ›
- Tadalafil ›
- Sumatriptan ›
- Valacyclovir ›
- Isotretinoin ›
- Hydroxyurea ›
- Prednisone ›
- Semaglutide ›
- Metformin ›
- Lisdexamfetamine ›
- Propranolol ›
- Amlodipine Besylate ›
- Amitriptyline ›
- Methotrexate ›
- Amphetamine ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Fluoxetine ›
- Bendamustine ›
- Doxycycline ›
- Pregabalin ›
- Azithromycin ›
- Levothyroxine, Liothyronine ›
- Lamotrigine ›
- Acyclovir ›
- Gabapentin ›
- Dextroamphetamine ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Omeprazole ›
- Buspirone ›
- Duloxetine ›
- Letrozole ›
- Acetaminophen, Codeine ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Partridgeberry list.
Partridgeberry References
The 2 sources that drive our Partridgeberry monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Partridgeberry is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
- Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Partridgeberry and Upadacitinib Hemihydrate Together: Common Questions
Is it safe to take Partridgeberry with Upadacitinib Hemihydrate?
Does Upadacitinib Hemihydrate interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.