Eryngo Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Eryngo interacts with medications. The heart of this page is the interaction list — every drug Eryngo is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Eryngo is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Eryngo against your medication
Add one medicationDrugs that interact with Eryngo
0 medications have a known interaction with Eryngo, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Eryngo. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Eryngo combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Eryngo: Uses, Safety & Side Effects
Eryngo is a thistle-like herb traditionally used as a diuretic and for urinary and respiratory complaints, but there is very little human research to confirm it actually works. Because its safety has not been well studied, it should be used cautiously and avoided during pregnancy and breastfeeding. Talk to a pharmacist or doctor before trying it.

- Scientific name
- Eryngium campestre
- Family
- Apiaceae
- Part used
- Root and aerial parts (herb)
- Common forms
- Tea (infusion or decoction), tincture, dried root, capsules
- Urinary tract complaints
- Diuretic (increasing urine flow)
- Respiratory infections and cough
- Kidney and bladder problems
- Menstrual pain
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Limited safety data exist, so use cautiously and only under guidance.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Eryngo is the common name for several plants in the genus Eryngium, which belongs to the carrot and parsley family (Apiaceae). The name is often used for Eryngium campestre (field eryngo) and the related coastal plant Eryngium maritimum, sometimes called sea holly. These are perennial herbs with spiky, blue-gray leaves and thistle-like flower heads.
Eryngo grows wild across Europe, the Mediterranean region, and North Africa, often in dry fields, sandy soils, and along coastlines. In traditional herbal medicine, the root is the part most often used, although the leaves and flowering tops are sometimes used as well.
People have traditionally taken eryngo as a tea or tincture, mainly as a diuretic and for urinary and respiratory complaints. The plant has also been used in cooking, including in pickling.
How it works
Eryngo contains a mix of plant compounds, including saponins, flavonoids, phenolic acids, and triterpenes such as those reported as eryngoside and related substances. In laboratory studies, some of these compounds have shown antioxidant, anti-inflammatory, and antimicrobial activity.
The traditional diuretic effect is thought to come from compounds that may increase urine production, while the anti-inflammatory and antimicrobial actions are proposed to explain its use for urinary and respiratory complaints.
It is important to understand that these mechanisms are mostly based on test-tube and animal studies. What happens in a lab dish does not always translate into a real benefit in the human body, and the doses needed are often unknown.
Does Eryngo work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Eryngo, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 1 condition — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Dysmenorrhea
A preliminary clinical study in women aged 15-30 years with primary dysmenorrhea, shows that taking 5 mL of an eryngo syrup, containing 486 mcg of total phenols and 375 mcg of total flavonoids, three times daily for the first 5 days of menstruation reduces pain similarly to ibuprofen syrup, 200 mg three times daily.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
There is very little formal safety research on eryngo, so its full risk profile is not known. Because it belongs to the carrot/parsley family (Apiaceae), people who are allergic to plants like carrots, celery, fennel, or related species may be at higher risk of an allergic reaction.
People with kidney disease should be especially careful with any herb used as a diuretic, and should check with a doctor first. If you have an ongoing infection, do not delay proper medical care.
Pregnancy: Avoid eryngo during pregnancy. There is not enough safety information, and some herbs used as diuretics or to affect menstruation could be risky.
Breastfeeding: Avoid eryngo while breastfeeding because its safety has not been studied in nursing mothers or infants.
Always tell your pharmacist or doctor about any herbal products you take, especially if you have a medical condition or take prescription medicines.
Side effects
Because eryngo has not been well studied in people, its side effects are not clearly documented. As with many herbal products, possible effects could include stomach upset or digestive discomfort.
Allergic reactions are possible, particularly in people sensitive to other plants in the Apiaceae family. Stop using it and seek medical care if you notice rash, itching, swelling, or trouble breathing.
Herbs used as diuretics may increase urine output, which in some people could affect fluid and electrolyte balance, especially if used heavily or for a long time.
Eryngo: Reported Adverse Effects
Documented safety reports on Eryngo from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, large doses of eryngo known as button eryngo may cause nausea and vomiting. No adverse effects have been reported for other types of eryngo; however, a high-quality assessment of safety has not been conducted.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established or standardized dose for eryngo. Traditional use typically involved a tea (infusion or decoction) made from the dried root or herb, but reliable, science-based dosing has not been determined.
If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount. Because product strength and quality can vary widely between brands, it is best to check with a pharmacist or doctor before starting, especially if you take other medications or have a health condition.
Eryngo & Pregnancy
Eryngo & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 2 references that drive our Eryngo monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Behmanesh E, Delavar MA, Kamalinejad M, Khafri S, Shirafkan H, Mozaffarpur SA. Effect of eryngo (Eryngium caucasicum Trautv) on primary dysmenorrhea: A randomized, double-blind, placebo-controlled study. Taiwan J Obstet Gynecol. 2019;58(2):227-33. doi: 10 PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Eryngo: Common Questions
What is Eryngo used for, and does it work?
Does Eryngo interact with prescription medications?
How are Eryngo interactions rated?
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Where does this Eryngo interaction information come from?
What is Eryngo used for?
Is Eryngo safe to take?
Can I take Eryngo if I'm pregnant or breastfeeding?
Can Eryngo cure a urinary tract infection?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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