Drug & supplement interaction

Relaxation Therapy + Crofelemer

Crofelemer brand names: Fulyzaq, Mytesi.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Relaxation Therapy and Crofelemer in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Relaxation Therapy and Crofelemer

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Crofelemer and Relaxation Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Relaxation Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Relaxation Therapy at all — not against Crofelemer, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Relaxation Therapy is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Relaxation Therapy safety at a glance

Relaxation Therapy overall Generally safe These techniques are generally very safe for most people.
Pregnancy Likely Safe When used appropriately. Relaxation therapy has been used in several clinical trials with apparent safety in pregnant women. Read the full pregnancy detail
Breastfeeding Generally safe Relaxation techniques are not known to pose risks while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Crofelemer and Relaxation Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Crofelemer’s Own FDA Label Lists

This is not an interaction — none of it involves Relaxation Therapy. These are the most notable effects listed in the ADVERSE REACTIONS section of Crofelemer’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you practice Relaxation Therapy and take the medicine. 2 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • A higher chance of infection Worth acting on
  • Bloating or gas
  • Back pain
  • Cough
  • Joint pain
  • Muscle pain
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Crofelemer. Read the label on DailyMed › Where a percentage is shown, it is the share of 233 voluntary FDA FAERS reports for Crofelemer that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Relaxation Therapy’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Relaxation Therapy side to compare — that is a limit of the record, not a statement that Relaxation Therapy has no side effects.

Special populations

Relaxation Therapy in Pregnancy & Breastfeeding

Pregnancy Likely Safe

When used appropriately. Relaxation therapy has been used in several clinical trials with apparent safety in pregnant women.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Crofelemer

This page covers Relaxation Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Crofelemer page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

Open the Crofelemer interaction page

How much people look this up

Where Relaxation Therapy and Crofelemer Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Relaxation Therapy
Steady interest

#1,368 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Crofelemer
Steady interest

#1,664 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Relaxation Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Relaxation Therapy and Crofelemer records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Mind-body practice

About Relaxation Therapy

What is Relaxation Therapy?

  • Anxiety and stress
  • Trouble sleeping
  • Chronic pain
  • High blood pressure
  • Headaches
  • Calming before medical procedures

Relaxation therapy is a group of mind-body techniques—like deep breathing, guided imagery, and progressive muscle relaxation—used to reduce stress and promote calm. It is low-risk for most people and has moderate evidence for easing anxiety, stress, and some pain or sleep problems. It is best used alongside, not instead of, standard medical care.

Not applicable (mind-body practice) · Guided imagery, progressive muscle relaxation, deep breathing, autogenic training, biofeedback, meditation

An interaction check asks whether these two react with each other — it does not ask whether Relaxation Therapy is a good idea for someone in your situation. Here is what our Relaxation Therapy record says about it on its own.

Relaxation Therapy: dosing

There is no standardized "dose" for relaxation therapy. Many programs suggest practicing for about 10 to 20 minutes once or twice a day, but what matters most is regular, consistent practice.You can use guided apps, audio recordings, classes, or work one-on-one with a therapist or biofeedback specialist.

From our Relaxation Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Relaxation Therapy monograph & all interactions
Medication

About Crofelemer

What Is Crofelemer Used For?

Brand names: Fulyzaq, Mytesi

Mytesi (crofelemer) is approved to provide symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.

It is not intended to treat diarrhea caused by an infection. Before starting Mytesi, a doctor will rule out infectious causes of diarrhea.

Most-Reported Side Effects for Crofelemer

From FAERS, the FDA’s public side-effect reporting system (233 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 26 reports
Anxiety 14 reports
Emotional distress 14 reports
Anhedonia 12 reports
Fatigue 11 reports
See full Crofelemer drug information
Keep checking

Other Drugs & Relaxation Therapy

Browse every other medication we’ve checked against Relaxation Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Relaxation Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Relaxation Therapy list.

See the full Relaxation Therapy interactions page
See every supplement checked against Crofelemer, ranked by severity
Evidence & sources

Relaxation Therapy References

The 5 references that drive our Relaxation Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Field T, Hernandez-Reif M, Hart S, et al. Pregnant women benefit from massage therapy. J Psychosom Obstet Gynaecol 1999;20(1):31-8. PubMed
  2. Janke J. The effect of relaxation therapy on preterm labor outcomes. J Obstet Gynecol Neonatal Nurs 1999;28(3):255-63. PubMed
  3. Little BC, Hayworth J, Benson P, et al. Treatment of hypertension in pregnancy by relaxation and biofeedback. Lancet 1984;1(8382):865-7. PubMed
  4. Khianman B, Pattanittum P, Thinkhamrop J, Lumbiganon P. Relaxation therapy for preventing and treating preterm labour. Cochrane Database Syst Rev. 2012;(8):CD007426. DOI
  5. Smith CA, Levett KM, Collins CT, Armour M, Dahlen HG, Suganuma M. Relaxation techniques for pain management in labour. Cochrane Database Syst Rev. 2018;3:CD009514. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Practicing Relaxation Therapy While Taking Crofelemer: Common Questions

Is it safe to practice Relaxation Therapy while taking Crofelemer?
We do not list a known interaction between Relaxation Therapy and Crofelemer. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Crofelemer interact with any supplements?
Yes. Crofelemer has documented interactions with 17 supplements in our database — Relaxation Therapy is not one of them. The Crofelemer interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Relaxation Therapy monograph Uses, safety profile, and every drug interaction in one place Crofelemer drug information The full plain-English guide to this medication Crofelemer supplement interactions Every supplement checked against Crofelemer, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Crofelemer and Relaxation Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.