Ground Pine Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Ground Pine interacts with medications. The heart of this page is the interaction list — every drug Ground Pine is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Ground Pine is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Ground Pine against your medication
Add one medicationDrugs that interact with Ground Pine
0 medications have a known interaction with Ground Pine, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Ground Pine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Ground Pine combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Ground Pine: Uses, Safety & Side Effects
Ground Pine (Ajuga chamaepitys) is a traditional European herb used mainly for joint pain, gout, and menstrual problems, but there is very little modern scientific evidence to support these uses. Because its safety has not been well studied, it should be used cautiously, and it should be avoided in pregnancy and breastfeeding. Talk to a pharmacist or doctor before trying it.
- Scientific name
- Ajuga chamaepitys
- Family
- Lamiaceae
- Part used
- Aerial parts (flowering tops, leaves, and stems)
- Common forms
- Dried herb, tea/infusion, tincture, liquid extract
- Joint pain and gout
- Mild fever
- Menstrual complaints
- Wound and skin care
- Digestive upset
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Little modern safety data exists, so use cautiously and only under guidance.
Traditionally linked to menstrual stimulation, so avoid during pregnancy.
No safety data in breastfeeding, so it is best avoided.
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Ground Pine (Ajuga chamaepitys) is a small, low-growing herb in the mint family. Despite its name, it is not a true pine tree — it got the name because its leaves give off a resinous, pine-like smell when crushed.
It grows mainly in Europe, the Mediterranean region, and parts of western Asia, often in dry, chalky soils and fields. The above-ground parts of the plant have been used in traditional European herbal medicine for many centuries.
Today it is sometimes found as a dried herb, tea, or tincture, but it is much less common than mainstream herbs and is mostly of historical and traditional interest.
Uses & effectiveness
Ground Pine has a long history of traditional use, but it has been studied very little in modern science. People have historically used it for:
- Joint pain and gout — a common traditional use, but not supported by strong clinical studies.
- Menstrual problems — traditionally used to encourage menstruation.
- Fever and mild infections — used in folk medicine, with little evidence.
- Wound care and skin issues — applied externally in some traditions.
- Digestive complaints — used as a bitter tonic.
Overall, the scientific evidence for Ground Pine is very limited. Most claims come from historical herbal texts rather than controlled human trials. There is not enough reliable evidence to say it works for any health condition.
How it works
Ground Pine contains plant compounds such as bitter substances, iridoid glycosides, diterpenes, and small amounts of volatile (aromatic) oils. These types of compounds are common in mint-family plants.
Some laboratory and animal research on related Ajuga species suggests possible anti-inflammatory or insect-affecting properties, but this work is early and does not prove the plant helps people. The exact way Ground Pine might act in the human body is not well understood.
In short, any proposed effects are based mostly on traditional use and limited lab studies, not on solid human evidence.
Safety & precautions
The safety of Ground Pine has not been carefully studied in people. Because of this lack of data, it should be used with caution, and only after speaking with a healthcare professional.
Pregnancy: Avoid. Ground Pine has traditionally been used to stimulate menstruation, which raises a concern about possible effects on the uterus. There is no safety information to support its use in pregnancy.
Breastfeeding: Avoid. There is no reliable information on whether its compounds pass into breast milk or are safe for a nursing baby.
People with liver problems, kidney problems, or chronic health conditions, and anyone taking regular medications, should check with a pharmacist or doctor before using it. Avoid giving it to children.
Side effects
Because Ground Pine has not been well studied, its full side-effect profile is unknown. As a bitter, aromatic herb, it could cause stomach upset, nausea, or digestive discomfort in some people.
Allergic reactions are possible, especially in people sensitive to other mint-family plants. Stop using it and seek medical care if you notice a rash, swelling, or trouble breathing.
As a general rule, avoid using large amounts or using it for long periods, since the long-term safety is not known.
Dosing
There is no established, standardized dose for Ground Pine. It has not been studied enough in modern research to define a safe and effective amount.
If you choose to use a commercial product, follow the directions on the label and do not exceed them. Because product quality and strength can vary widely, it is best to talk with a pharmacist or doctor first.
Do not assume that 'natural' means safe at any dose — more is not better with herbs that have limited safety data.
References & further reading
The 2 sources that drive our Ground Pine monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.
- Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
- Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Ground Pine: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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