Herb & supplement monograph

Ground Pine Drug Interactions, Uses, Safety & More

Check Ground Pine against your medication

Add one medication
Ground Pine
+
Start typing any prescription or over-the-counter drug name.
Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Ground Pine

0 medications have a known interaction with Ground Pine, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Ground Pine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Ground Pine combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Ground Pine: Uses, Safety & Side Effects

The bottom line

Ground Pine (Ajuga chamaepitys) is a traditional European herb used mainly for joint pain, gout, and menstrual problems, but there is very little modern scientific evidence to support these uses. Because its safety has not been well studied, it should be used cautiously, and it should be avoided in pregnancy and breastfeeding. Talk to a pharmacist or doctor before trying it.

Scientific name
Ajuga chamaepitys
Family
Lamiaceae
Part used
Aerial parts (flowering tops, leaves, and stems)
Common forms
Dried herb, tea/infusion, tincture, liquid extract
People commonly use it for
  • Joint pain and gout
  • Mild fever
  • Menstrual complaints
  • Wound and skin care
  • Digestive upset

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Little modern safety data exists, so use cautiously and only under guidance.

PregnancyBest avoided

Traditionally linked to menstrual stimulation, so avoid during pregnancy.

BreastfeedingBest avoided

No safety data in breastfeeding, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Ground Pine (Ajuga chamaepitys) is a small, low-growing herb in the mint family. Despite its name, it is not a true pine tree — it got the name because its leaves give off a resinous, pine-like smell when crushed.

It grows mainly in Europe, the Mediterranean region, and parts of western Asia, often in dry, chalky soils and fields. The above-ground parts of the plant have been used in traditional European herbal medicine for many centuries.

Today it is sometimes found as a dried herb, tea, or tincture, but it is much less common than mainstream herbs and is mostly of historical and traditional interest.

Uses & effectiveness

Ground Pine has a long history of traditional use, but it has been studied very little in modern science. People have historically used it for:

  • Joint pain and gout — a common traditional use, but not supported by strong clinical studies.
  • Menstrual problems — traditionally used to encourage menstruation.
  • Fever and mild infections — used in folk medicine, with little evidence.
  • Wound care and skin issues — applied externally in some traditions.
  • Digestive complaints — used as a bitter tonic.

Overall, the scientific evidence for Ground Pine is very limited. Most claims come from historical herbal texts rather than controlled human trials. There is not enough reliable evidence to say it works for any health condition.

How it works

Ground Pine contains plant compounds such as bitter substances, iridoid glycosides, diterpenes, and small amounts of volatile (aromatic) oils. These types of compounds are common in mint-family plants.

Some laboratory and animal research on related Ajuga species suggests possible anti-inflammatory or insect-affecting properties, but this work is early and does not prove the plant helps people. The exact way Ground Pine might act in the human body is not well understood.

In short, any proposed effects are based mostly on traditional use and limited lab studies, not on solid human evidence.

Safety & precautions

The safety of Ground Pine has not been carefully studied in people. Because of this lack of data, it should be used with caution, and only after speaking with a healthcare professional.

Pregnancy: Avoid. Ground Pine has traditionally been used to stimulate menstruation, which raises a concern about possible effects on the uterus. There is no safety information to support its use in pregnancy.

Breastfeeding: Avoid. There is no reliable information on whether its compounds pass into breast milk or are safe for a nursing baby.

People with liver problems, kidney problems, or chronic health conditions, and anyone taking regular medications, should check with a pharmacist or doctor before using it. Avoid giving it to children.

Side effects

Because Ground Pine has not been well studied, its full side-effect profile is unknown. As a bitter, aromatic herb, it could cause stomach upset, nausea, or digestive discomfort in some people.

Allergic reactions are possible, especially in people sensitive to other mint-family plants. Stop using it and seek medical care if you notice a rash, swelling, or trouble breathing.

As a general rule, avoid using large amounts or using it for long periods, since the long-term safety is not known.

Dosing

There is no established, standardized dose for Ground Pine. It has not been studied enough in modern research to define a safe and effective amount.

If you choose to use a commercial product, follow the directions on the label and do not exceed them. Because product quality and strength can vary widely, it is best to talk with a pharmacist or doctor first.

Do not assume that 'natural' means safe at any dose — more is not better with herbs that have limited safety data.

References & further reading

The 2 sources that drive our Ground Pine monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
  2. Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Pharmacist Counseling Corner

Ground Pine: Common Questions

Does Ground Pine interact with prescription medications?
We do not currently list any known drug interactions for Ground Pine. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Ground Pine interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Ground Pine with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Ground Pine interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Ground Pine used for?
Traditionally it has been used for joint pain, gout, menstrual complaints, fever, and digestive upset. However, there is very little modern scientific evidence that it works for any of these.
Is Ground Pine the same as a pine tree?
No. Ground Pine is a small herb in the mint family. It got its name because its crushed leaves smell resinous, similar to pine, not because it is related to pine trees.
Is Ground Pine safe to take?
Its safety has not been well studied, so it should be used cautiously and only after checking with a pharmacist or doctor. Avoid it if you are pregnant, breastfeeding, or giving it to children.
Can I take Ground Pine during pregnancy?
No. It has traditionally been used to bring on menstruation, and there is no safety data for pregnancy, so it should be avoided.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Have a question about Ground Pine?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist