Herb & supplement monograph

Dragon's Blood Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Dragon's Blood

0 medications have a known interaction with Dragon's Blood, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Dragon's Blood. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Dragon's Blood combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Dragon's Blood: Uses, Safety & Side Effects

The bottom line

Dragon's Blood is a red plant resin used in traditional medicine for wound healing, skin problems, and digestive complaints. Some early research on certain types (especially Croton lechleri "Sangre de Drago") is promising for the gut and skin, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially while pregnant or breastfeeding.

Dragon's Blood
Part used
Red resin (sap) from the bark, stem, or fruit, depending on the source plant
Common forms
Resin powder, capsules, tinctures, topical liquids, creams, and skincare products
People commonly use it for
  • Wound healing and skin care
  • Digestive upset and diarrhea
  • Minor cuts and insect bites
  • Sore throat and mouth sores
  • Anti-inflammatory skincare

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Topical use is generally considered low-risk for most people, but human safety data are limited and product sources vary.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Dragon's Blood is the name for a deep red resin or sap that comes from several different plants. The name is shared by more than one source, which can be confusing. One common source is a palm tree called Daemonorops draco from Southeast Asia. Another well-known source is a South American tree often called Croton lechleri, whose red sap is known as Sangre de Drago ("blood of the dragon").

Because the bright red color looks like blood, the resin has been valued for centuries. It has been used in traditional medicine, as a dye or varnish, and in incense and rituals. Today it shows up in folk remedies, dietary supplements, and skincare products.

People most often use Dragon's Blood on the skin for wounds and irritation, or take it by mouth for digestive complaints. The type sold matters, since different plants have different chemistry.

Uses & effectiveness

Dragon's Blood is traditionally used as an astringent (something that tightens tissue), for wound healing, and for stomach and bowel problems such as diarrhea. People also apply it to cuts, scrapes, insect bites, and minor skin irritation, and use it for sore throats and mouth sores.

The honest summary is that good human evidence is limited. The strongest research has looked at Sangre de Drago (from Croton lechleri). A purified compound from that sap has been studied for certain types of diarrhea, and some laboratory and small studies suggest the resin may help skin and gut tissue. Even so, the quality and amount of human research is not enough to consider most uses proven.

For the palm-derived Daemonorops type of Dragon's Blood, there is even less reliable human research. Much of what is known comes from laboratory or animal studies, which do not always apply to people. If you are considering Dragon's Blood for a health problem, treat it as unproven and check with a healthcare professional.

How it works

Dragon's Blood resin contains a mix of natural compounds, including proanthocyanidins (a type of plant tannin), and pigments such as dracorubin and related red coloring molecules. Depending on the plant source, it may also contain alkaloids like taspine and various other phenolic compounds.

Researchers think the tannins give it astringent properties, meaning they can tighten and protect tissue and may help form a protective layer over wounds. Some compounds appear to have antioxidant, anti-inflammatory, and antimicrobial activity in the lab. Certain components have also been studied for effects on fluid movement in the gut, which is one proposed reason for use in diarrhea.

It is important to know that most of these mechanisms come from test-tube and animal research. Showing an effect in a lab dish does not prove the same benefit when a person uses the product.

Safety & precautions

For most adults, applying Dragon's Blood to the skin for a short time appears to be relatively low-risk, but solid human safety data are limited. Quality and purity can vary a lot between products, and some products may be mislabeled or come from a different plant than expected.

Be cautious if you have allergies to plants or resins, sensitive skin, or a chronic medical condition. Do a small patch test before using a topical product over a large area. Avoid putting it into deep or serious wounds without medical advice.

Pregnancy and breastfeeding: there is not enough reliable safety information, so it is best to avoid Dragon's Blood during pregnancy and while breastfeeding. Do not give Dragon's Blood to infants or children unless directed by a pediatric clinician. When in doubt, ask your pharmacist or doctor before using it.

Side effects

Reported side effects are not well documented because high-quality studies are limited. When used on the skin, the most likely problems are local irritation, redness, itching, or an allergic skin reaction, especially in people sensitive to plant resins.

When taken by mouth, it may cause stomach upset or other digestive symptoms in some people. Because tannins can be strong, large amounts taken internally could be harsh on the stomach.

Stop using it and seek medical care if you notice signs of an allergic reaction, such as a spreading rash, swelling, or trouble breathing. As with any supplement, contamination or mislabeling is a concern, so choose products from reputable companies.

Dosing

There is no established standard dose for Dragon's Blood. The right amount depends on the specific plant source, the product type (resin, tincture, capsule, or cream), and how it is being used.

If you choose to use a Dragon's Blood product, follow the directions on the label and do not exceed the suggested amount. For skin products, apply a small amount and watch for irritation first.

Because dosing is not well defined and products differ, it is smart to check with a pharmacist or doctor before starting, especially if you take medications or have a health condition.

Pregnancy & Breastfeeding

Dragon's Blood & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Dragon's Blood & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 sources that drive our Dragon's Blood monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Product directory

Supplement products with Dragon's Blood

27 products in our database contain Dragon's Blood. Open any to see its full ingredient list and every drug interaction we check.

Ageless Brain by Organixx Capsule 60 Veggie Cap(s) View ingredients & interactions Aroma Resins by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Aroma Resins by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Aroma Resins Alcohol Free by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Aroma Resins Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon Blood Non-Alcohol by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Dragon's Blood by Herb Pharm Liquid 1 Fluid Ounce · 30 mL View ingredients & interactions Dragon's Blood 450 mg 4:1 Extract by TerraVita Premium Collection Capsule 100 Capsule(s) View ingredients & interactions Dragon's Blood Powder by TerraVita Premium Collection Powder 1 oz View ingredients & interactions Dragon's Blood Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Memory Plus by Remedys Nutrition Capsule 60 Vcap(s) View ingredients & interactions Resinall E Tabs by Health Concerns Tablet Or Pill 60 Tablet(s) View ingredients & interactions Resinall K by Health Concerns Liquid 1 Fluid Ounce(s) View ingredients & interactions Resinall K by Health Concerns Liquid 1 Fluid Ounce View ingredients & interactions Ageless Brain by Organixx Capsule 60 Veggie Cap(s) Off market View ingredients & interactions Aroma Resins by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL Off market View ingredients & interactions Aroma Resins Non-Alcohol by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL Off market View ingredients & interactions Dragon's Blood by Herb Pharm Liquid 1 fl. Oz. · 30 mL Off market View ingredients & interactions
Pharmacist Counseling Corner

Dragon's Blood: Common Questions

Does Dragon's Blood interact with prescription medications?
We do not currently list any known drug interactions for Dragon's Blood. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Dragon's Blood interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Dragon's Blood with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Dragon's Blood interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Dragon's Blood used for?
It is traditionally used on the skin for wounds, cuts, and irritation, and taken by mouth for digestive problems like diarrhea. Most of these uses are based on tradition and early research rather than strong human evidence.
Is Dragon's Blood safe?
Short-term use on the skin is generally considered low-risk for most adults, but human safety data are limited and product quality varies. Use a small patch test first and talk to your pharmacist if you plan to take it by mouth.
Can I use Dragon's Blood while pregnant or breastfeeding?
It is best to avoid it, since there is not enough information to know whether it is safe during pregnancy or breastfeeding. Ask your doctor before using any herbal product at these times.
Is all Dragon's Blood the same?
No. The name is used for red resin from several different plants, such as a Southeast Asian palm (Daemonorops) and a South American tree (Croton lechleri). Their chemistry differs, so effects and quality can vary between products.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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