Relaxation Therapy + Midazolam
Midazolam brand names: Versed, Seizalam, Nayzilam.
We found no known interaction between Relaxation Therapy and Midazolam in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Relaxation Therapy and Midazolam
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Midazolam and Relaxation Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Relaxation Therapy alongside specific medications may be limited.
Worth understanding: our licensed dataset holds no drug-interaction record for Relaxation Therapy at all — not against Midazolam, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
Relaxation Therapy is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Relaxation Therapy safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Relaxation Therapy in Pregnancy & Breastfeeding
When used appropriately. Relaxation therapy has been used in several clinical trials with apparent safety in pregnant women.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Midazolam Is Prescribed For, and What Relaxation Therapy Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Midazolam is a prescription medicine with approved uses on its FDA label. Relaxation Therapy is a practice: what follows is what researchers have looked at it for, and how strong that evidence is.
Midazolam is prescribed for: Midazolam is used in several different forms depending on the setting. Injectable midazolam (given by IV or IM shot) is used before and during surgery or procedures — such as endoscopy, cardiac catheterization, or bronchoscopy — to cause sedation, reduce anxiety, and prevent memory of the event. It can also be used to start general anesthesia or to keep heavily sedated, ventilated patients comfortable in a critical care unit. Midazolam HCl oral syrup is used specifically in children for sedation and anxiety relief before procedures or anesthesia induction, in a monitored medical setting only.
Read the rest of what Midazolam is prescribed for
Nayzilam nasal spray is indicated for a different purpose: the acute treatment of seizure clusters (also called acute repetitive seizures) in people aged 12 and older who have epilepsy. It is used intermittently — not as a daily seizure medicine — when a cluster of seizures breaks through the person's usual pattern.
Relaxation Therapy has been studied for:
-
Epilepsy studied, not established Relaxation Therapy has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Relaxation Therapy for epilepsy
Although there has been interest in the practice of relaxation therapy for epilepsy, there is insufficient reliable information about the clinical effects of relaxation therapy for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Midazolam on your own; if you are taking Relaxation Therapy for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Midazolam
This page covers Relaxation Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Midazolam page lists 202 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Bitter Orange (major) and Fever Bark (major).
By severity: 11 major · 153 moderate · 38 minor.
From our pharmacist’s overview on the Midazolam page
“Sedation stacked on sedation is the headline risk with midazolam (Versed, Seizalam, Nayzilam). Midazolam is a benzodiazepine used for sedation and seizure emergencies, and 78 of the 202 interacting ingredients here, beer and wine included, add their own drowsiness, which can slide into dangerously slowed breathing.”
Reviewed by 2 · Jul 18, 2026
Where Relaxation Therapy and Midazolam Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,362 of 1,452 supplements looked up here in the last 7 days
#1,245 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Relaxation Therapy reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Relaxation Therapy and Midazolam records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Relaxation Therapy
What is Relaxation Therapy?
- Anxiety and stress
- Trouble sleeping
- Chronic pain
- High blood pressure
- Headaches
- Calming before medical procedures
Relaxation therapy is a group of mind-body techniques—like deep breathing, guided imagery, and progressive muscle relaxation—used to reduce stress and promote calm. It is low-risk for most people and has moderate evidence for easing anxiety, stress, and some pain or sleep problems. It is best used alongside, not instead of, standard medical care.
Not applicable (mind-body practice) · Guided imagery, progressive muscle relaxation, deep breathing, autogenic training, biofeedback, meditation
An interaction check asks whether these two react with each other — it does not ask whether Relaxation Therapy is a good idea for someone in your situation. Here is what our Relaxation Therapy record says about it on its own.
Relaxation Therapy: dosing
There is no standardized "dose" for relaxation therapy. Many programs suggest practicing for about 10 to 20 minutes once or twice a day, but what matters most is regular, consistent practice.You can use guided apps, audio recordings, classes, or work one-on-one with a therapist or biofeedback specialist.
From our Relaxation Therapy monograph — the full record covers uses, side effects and every documented interaction.
About Midazolam
What Is Midazolam Used For?
Brand names: Versed, Seizalam, Nayzilam
Midazolam is used in several different forms depending on the setting. Injectable midazolam (given by IV or IM shot) is used before and during surgery or procedures — such as endoscopy, cardiac catheterization, or bronchoscopy — to cause sedation, reduce anxiety, and prevent memory of the event. It can also be used to start general anesthesia or to keep heavily sedated, ventilated patients comfortable in a critical care unit. Midazolam HCl oral syrup is used specifically in children for sedation and anxiety relief before procedures or anesthesia induction, in a monitored medical setting only.
Nayzilam nasal spray is indicated for a different purpose: the acute treatment of seizure clusters (also called acute repetitive seizures) in people aged 12 and older who have epilepsy. It is used intermittently — not as a daily seizure medicine — when a cluster of seizures breaks through the person's usual pattern.
Most-Reported Side Effects for Midazolam
From FAERS, the FDA’s public side-effect reporting system (29,268 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Relaxation Therapy
Browse every other medication we’ve checked against Relaxation Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Relaxation Therapy against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Relaxation Therapy list.
Relaxation Therapy References
The 5 references that drive our Relaxation Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Field T, Hernandez-Reif M, Hart S, et al. Pregnant women benefit from massage therapy. J Psychosom Obstet Gynaecol 1999;20(1):31-8. PubMed
- Janke J. The effect of relaxation therapy on preterm labor outcomes. J Obstet Gynecol Neonatal Nurs 1999;28(3):255-63. PubMed
- Little BC, Hayworth J, Benson P, et al. Treatment of hypertension in pregnancy by relaxation and biofeedback. Lancet 1984;1(8382):865-7. PubMed
- Khianman B, Pattanittum P, Thinkhamrop J, Lumbiganon P. Relaxation therapy for preventing and treating preterm labour. Cochrane Database Syst Rev. 2012;(8):CD007426. DOI
- Smith CA, Levett KM, Collins CT, Armour M, Dahlen HG, Suganuma M. Relaxation techniques for pain management in labour. Cochrane Database Syst Rev. 2018;3:CD009514. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Practicing Relaxation Therapy While Taking Midazolam: Common Questions
Is it safe to practice Relaxation Therapy while taking Midazolam?
Are Relaxation Therapy and Midazolam used for the same thing?
Does Midazolam interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Midazolam and Relaxation Therapy?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.