Drug & supplement interaction

Sour Cherry + Adapalene, Benzoyl Peroxide

Adapalene, Benzoyl Peroxide brand names: Tactuo, Epiduo Forte.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Sour Cherry and Adapalene, Benzoyl Peroxide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Sour Cherry and Adapalene, Benzoyl Peroxide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Adapalene, Benzoyl Peroxide and Sour Cherry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sour Cherry at all — not against Adapalene, Benzoyl Peroxide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sour Cherry safety at a glance

Sour Cherry overall Use caution Generally well tolerated as a food, but concentrated products are less studied.
Pregnancy Likely Safe When the fruit is consumed in typical food amounts. There is insufficient reliable information available about the safety of tart cherry fruit or stem when used... Read the full pregnancy detail
Breastfeeding Likely Safe When the fruit is consumed in typical food amounts. There is insufficient reliable information available about the safety of tart cherry fruit or stem when used... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Adapalene, Benzoyl Peroxide and Sour Cherry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sour Cherry Itself Has Been Linked To

This is not an interaction — nothing below involves Adapalene, Benzoyl Peroxide. It is the side-effect record for Sour Cherry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Sour Cherry, this list is the first place to look.

  • Stomach upset / Stomach pain / Diarrhea Additional detail

    “In a clinical study, 29% of children who consumed 75 mL of tart cherry juice concentrate twice daily for 2 weeks reported abdominal pain. Two cases of loose stools after consumption of 90 whole tart cherries, and one case of gastrointestinal disturbance after drinking 10.5 ounces of tart cherry concentrate (Cherrish, Cherrish Corp.) twice daily for 14 days have been reported.”

    Sour Cherry · Natural Medicines adverse-effect record, reported in pain.

    4 sources cited
    1. 112815. Soltanifar A, Moharreri F, Bakhtiari E, Hosseinpour A. The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children. J Atten Disord 2023;27(2):214-219. PubMed
    2. 93186. Seymour EM, Warber SM, Kirakosyan A, et al. Anthocyanin pharmacokinetics and dose-dependent plasma antioxidant pharmacodynamics following whole tart cherry intake in healthy humans. J Funct Food 2014;11:509-16. DOI
    3. 93192. Elliot DL, Kuehl KS, Jones KD, Dulacki K. Using an eccentric exercise-testing protocol to assess the beneficial effects of tart cherry juice in fibromyalgia patients. Integ Med 2010;9(6):25-9.
    4. 93160. Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
  • Tiredness Additional detail

    Recorded for Sour Cherry in the same Natural Medicines adverse-effect record shown under Stomach upset / Stomach pain / Diarrhea above.

Everything above comes from the Natural Medicines adverse-effect record for Sour Cherry — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Adapalene, Benzoyl Peroxide’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Adapalene, Benzoyl Peroxide column appears here.

Special populations

Sour Cherry in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When the fruit is consumed in typical food amounts. There is insufficient reliable information available about the safety of tart cherry fruit or stem when used in medicinal amounts; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Adapalene, Benzoyl Peroxide

This page covers Sour Cherry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Adapalene, Benzoyl Peroxide page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Adapalene, Benzoyl Peroxide page

“Adapalene with benzoyl peroxide (Epiduo Forte, Tactuo) is an acne gel that works on the skin surface, so its supplement interactions are fewer and quieter than most oral medicines carry. Only three ingredients appear here, none rated major, and every one of them is something applied to the skin rather than swallowed.”

Reviewed by 2 · Jul 18, 2026

Open the Adapalene, Benzoyl Peroxide interaction page

One more smart check

Taking Sour Cherry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,479 real supplement products containing Sour Cherry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sour Cherry. Even though Sour Cherry itself has no known interaction with Adapalene, Benzoyl Peroxide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Sour Cherry and Adapalene, Benzoyl Peroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sour Cherry
Top 25%

#156 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Adapalene, Benzoyl Peroxide
Steady interest

#1,598 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sour Cherry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Sour Cherry and Adapalene, Benzoyl Peroxide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sour Cherry

What is Sour Cherry?

  • Muscle soreness after exercise
  • Gout and joint discomfort
  • Sleep support
  • Arthritis pain
  • General antioxidant support

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, joint and gout symptoms, and sleep. Early research is promising but limited, so it is not a proven treatment. It is generally well tolerated as a food, but talk to your pharmacist or doctor before using concentrated products.

Prunus cerasus · Rosaceae · Fruit (and fruit juice or concentrate) · Juice, concentrate, capsules, powder, dried fruit, extract

An interaction check asks whether these two react with each other — it does not ask whether Sour Cherry is a good idea for someone in your situation. Here is what our Sour Cherry record says about it on its own.

Sour Cherry: dosing

There is no official or standardized dose for sour cherry supplements. Studies have used different forms and amounts, including juice, concentrate, and capsules, so there is no single agreed-upon dose.The best approach is to follow the directions on the product label and not exceed them.

From our Sour Cherry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sour Cherry monograph & all interactions
Keep checking

Other Drugs & Sour Cherry

Browse every other medication we’ve checked against Sour Cherry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Sour Cherry References

The 4 references that drive our Sour Cherry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
  2. Seymour EM, Warber SM, Kirakosyan A, et al. Anthocyanin pharmacokinetics and dose-dependent plasma antioxidant pharmacodynamics following whole tart cherry intake in healthy humans. J Funct Food 2014;11:509-16. DOI
  3. Elliot DL, Kuehl KS, Jones KD, Dulacki K. Using an eccentric exercise-testing protocol to assess the beneficial effects of tart cherry juice in fibromyalgia patients. Integ Med 2010;9(6):25-9.
  4. Soltanifar A, Moharreri F, Bakhtiari E, Hosseinpour A. The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children. J Atten Disord 2023;27(2):214-219. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Sour Cherry and Adapalene, Benzoyl Peroxide Together: Common Questions

Is it safe to take Sour Cherry with Adapalene, Benzoyl Peroxide?
We do not list a known interaction between Sour Cherry and Adapalene, Benzoyl Peroxide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Adapalene, Benzoyl Peroxide interact with any supplements?
Yes. Adapalene, Benzoyl Peroxide has documented interactions with 3 supplements in our database — Sour Cherry is not one of them. The Adapalene, Benzoyl Peroxide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Adapalene, Benzoyl Peroxide and Sour Cherry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.