Mugwort Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Mugwort interacts with medications. The heart of this page is the interaction list — every drug Mugwort is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Mugwort is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Mugwort against your medication
Add one medicationDrugs that interact with Mugwort
0 medications have a known interaction with Mugwort, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Mugwort. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Mugwort combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Mugwort: Uses, Safety & Side Effects
Mugwort is a traditional herb used for digestion, menstrual issues, and sleep, but there is very little high-quality human research to confirm these uses. It is closely related to ragweed and can trigger allergic reactions, and it should be avoided in pregnancy. Talk with your pharmacist or doctor before using it.

- Scientific name
- Artemisia vulgaris
- Family
- Asteraceae
- Part used
- Leaves, flowering tops, and root; sometimes essential oil
- Common forms
- Tea, capsules, tincture, dried herb, essential oil, and moxa (used in moxibustion)
- Digestive upset and poor appetite
- Menstrual discomfort
- Sleep support and vivid dreaming
- Used in moxibustion (traditional Chinese medicine)
- Mild anxiety or relaxation
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
May cause allergic reactions, especially in people sensitive to ragweed and related plants.
When used orally. Mugwort is said to be an abortifacient and a menstrual and uterine stimulant.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Mugwort (Artemisia vulgaris) is a tall, aromatic perennial plant in the daisy family. It is native to Europe and Asia and now grows in many parts of North America, often as a roadside weed.
People have used mugwort for centuries in traditional European, Asian, and folk medicine. The leaves and flowering tops are dried for teas, tinctures, and capsules. In traditional Chinese medicine, dried mugwort is also burned near the skin in a practice called moxibustion.
Today it is sold as a dietary supplement and herbal tea, and people use it mainly for digestion, menstrual symptoms, and sleep. It also has a long history in spiritual and cultural traditions.
How it works
Mugwort contains a mix of plant compounds, including volatile oils (such as cineole and thujone), flavonoids, and bitter substances called sesquiterpene lactones.
The bitter compounds are thought to stimulate digestive juices, which is the traditional reason it is used for the stomach. Its essential oils may have mild effects on muscles, which could explain its folk use for menstrual symptoms.
Most of these ideas come from laboratory or animal research, not from well-designed human trials. So while these mechanisms are plausible, they do not prove that mugwort works or is safe in people.
Does Mugwort work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Mugwort, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 8 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Anxiety
Although there has been interest in using oral mugwort root for anxiety, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Colic
Although there has been interest in using oral mugwort for colic, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Dysmenorrhea
Although there has been interest in using oral mugwort for dysmenorrhea, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Epilepsy
Although there has been interest in using oral mugwort for epilepsy, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Hypertension
Although there has been interest in using oral mugwort for hypertension, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Hypertrophic scars
Topical mugwort has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Insufficient Reliable Evidence To Rate Insomnia
Although there has been interest in using oral mugwort root for insomnia, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Insufficient Reliable Evidence To Rate Intestinal parasite infection
Although there has been interest in using oral mugwort for intestinal parasite infections, there is insufficient reliable information about the clinical effects of mugwort for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Mugwort is part of the same plant family as ragweed, daisies, marigolds, and chrysanthemums. People allergic to these plants may react to mugwort. It is also a well-known cause of pollen allergy and can be linked to food allergies (sometimes called "celery-mugwort-spice syndrome").
Mugwort essential oil contains thujone, which can be toxic in large amounts. Concentrated oils should not be taken by mouth.
Pregnancy: Avoid mugwort. It has traditionally been used to bring on menstruation and may stimulate the uterus, which could be harmful during pregnancy.
Breastfeeding: Avoid mugwort because there is not enough safety information.
People with allergies, asthma, or who are taking other medicines should check with a pharmacist or doctor before using it.
Side effects
For many people, small amounts of mugwort tea cause few problems, but reactions can occur.
Possible side effects include:
- Allergic reactions such as skin rash, itching, sneezing, or runny nose
- Contact dermatitis (skin irritation) from handling the plant
- Stomach upset
Rarely, mugwort can trigger serious allergic reactions, including severe breathing problems (anaphylaxis), especially in people with plant or pollen allergies. Stop using it and seek medical care if you have trouble breathing, swelling, or hives. Large doses of products containing thujone may be harmful.
Mugwort: Reported Adverse Effects
Documented safety reports on Mugwort from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Reports by conditionAllergic rhinitis (hay fever) Immunologic
Allergy to mugwort pollen has been reported when taken orally or inhaled. Symptoms have included asthma, rhinitis, conjunctivitis, rash, and anaphylaxis.
- Borghesan F, Mistrello G, Amato S, Giuffrida MG, Villalta D, Asero R. Mugwort-fennel-allergy-syndrome associated with sensitization to an allergen homologous to Api g 5. Eur Ann Allergy Clin Immunol. 2013;45(4):130-7.
- Kim SH, Lee SM, Park HW, et al. Chinese bellflower root anaphylaxis: IgE-binding components and cross-reactivity with mugwort and birch. Korean J Intern Med. 2009;24(3):279-82.
- Silva R, Lopes C, Castro E, et al. Anaphylaxis to mango fruit and crossreactivity with Artemisia vulgaris pollen. J Investig Allergol Clin Immunol. 2009;19(5):420-2.
- Rodrigues-Alves R, Pregal A, Pereira-Santos MC, et al. Anaphylaxis to pine nut: cross-reactivity to Artemisia vulgaris? Allergol Immunopathol (Madr). 2008;36(2):113-6.
Poisoning Psychiatric
Orally, mania has been reported in a 49-year-old male following the intake of 1 liter of an infusion thought to contain mugwort. The presence of thujone in the patient's serum and urine was confirmed, and thujone poisoning was considered to be the cause of these symptoms. Although thujone levels are normally low in mugwort, concentrations can be variable. It was postulated that the mugwort infusion contained an unusually high amount of thujone. It was also considered to be possible that the metabolism of thujone was decreased in this particular patient or that the poisoning was related to the chronic intake of small amounts. However, a sample of the plant was not analyzed, and adulteration or contamination by a related species cannot be ruled out.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established, standardized dose for mugwort. The amount in teas, capsules, and tinctures varies a lot between products.
If you choose to use mugwort, follow the directions on the product label and do not exceed them. Avoid swallowing the concentrated essential oil. Because doses are not standardized and quality can vary, it is wise to talk with a pharmacist or doctor first, especially if you have allergies or take other medicines.
Mugwort & Pregnancy
Mugwort & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 7 references that drive our Mugwort monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Borghesan F, Mistrello G, Amato S, Giuffrida MG, Villalta D, Asero R. Mugwort-fennel-allergy-syndrome associated with sensitization to an allergen homologous to Api g 5. Eur Ann Allergy Clin Immunol. 2013;45(4):130-7.
- Kim SH, Lee SM, Park HW, et al. Chinese bellflower root anaphylaxis: IgE-binding components and cross-reactivity with mugwort and birch. Korean J Intern Med. 2009;24(3):279-82. PubMed
- Silva R, Lopes C, Castro E, et al. Anaphylaxis to mango fruit and crossreactivity with Artemisia vulgaris pollen. J Investig Allergol Clin Immunol. 2009;19(5):420-2.
- Rodrigues-Alves R, Pregal A, Pereira-Santos MC, et al. Anaphylaxis to pine nut: cross-reactivity to Artemisia vulgaris? Allergol Immunopathol (Madr). 2008;36(2):113-6. PubMed
- Di Lorenzo C, Ferretti F, Moro E, et al. Identification and quantification of thujone in a case of poisoning due to repeated ingestion of an infusion of Artemisia vulgaris L. J Food Sci. 2018;83(8):2257-2264.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Mugwort
23 brands in our database make a supplement containing Mugwort.
Supplement products with Mugwort
88 products in our database contain Mugwort. Open any to see its full ingredient list and every drug interaction we check.
Mugwort: Common Questions
What is Mugwort used for, and does it work?
Does Mugwort interact with prescription medications?
How are Mugwort interactions rated?
Is it safe to take Mugwort with my medications?
Where does this Mugwort interaction information come from?
What is Mugwort used for?
Is Mugwort safe to take?
Can I use Mugwort while pregnant or breastfeeding?
Does Mugwort cause vivid dreams?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Mugwort
A rotating sample of real supplements in our database that list Mugwort — open any to see its full ingredients and every drug interaction we check.
- Dream Trap by Hawaii Pharm
- Herbal Alkalizer by MBi Nutraceuticals
- Mugwort by Herbal Terra
- Happy Mood Enhancer by New Sun
- Mugwort Herb Chocolate Flavor by TerraVita
- Dream Trap Non-Alcohol by Hawaii Pharm
- Mugwort Herb (Artemisia vulgaris) Powder by TerraVita Premium Collection
- Parasite Support by TerraVita
- Joy Tonic by Urban Moonshine
- Mugwort Herb (Artemisia vulgaris) (Certified Organic) Powder by TerraVita Premium Collection
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