Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Joy Tonic Ingredients & Drug Interactions

by Urban Moonshine

Joy Tonic label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Joy Tonic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Joy Tonic is a dietary supplement by Urban Moonshine with 6 active ingredients. Its ingredients are commonly taken for anxiety and stress, heart palpitations, menstrual discomfort.Based on those ingredients, 859 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are org. Lemongrass extract, org. Lemon Balm leaf extract, organic Motherwort leaf and flower extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Joy Tonic by Urban Moonshine

Ask about any prescription or over-the-counter medication and we check it for interactions with Joy Tonic by Urban Moonshine — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Joy Tonic by Urban Moonshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Herbal Extract Blend (Herb/Botanical)” is a proprietary blend — the label gives one combined amount (5 mL) without saying how much of each component you get.

Joy Tonic contains six active botanical ingredients. The formula includes a proprietary herbal extract blend (the exact botanicals aren't itemized on the label), plus individual extracts of rose petals, motherwort leaf and flower, linden leaf and flower, lemongrass, mugwort leaf, and lemon balm leaf.

The product also contains water and organic alcohol as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Mindfully let go of tension and promote joy.
  • We looked for evidence on: Anxiety, Stress, Insomnia, Emotional balance, Relaxation, Well-being.
  • The strongest evidence on file: Lemon Balm is rated "Possibly Effective" for Stress (Natural Medicines).
  • Also on file: Mugwort is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Insomnia.
  • Also on file: Motherwort is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Insomnia.

The evidence for most ingredients in this formula is limited. Lemon balm is possibly effective for cold sores, stress, and depression according to our data.

Motherwort is possibly effective for bleeding, though evidence for its other traditional uses — including anxiety and amenorrhea — is insufficient. For linden, lemongrass, mugwort, and rose petal, either no effectiveness ratings are on file or the evidence for their claimed uses is insufficient to rate.

This product markets itself as a mood and nervous-system tonic, but the scientific backing for that specific purpose isn't established in our data.

The evidence, ingredient by ingredient Motherwort Linden Lemongrass Mugwort Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Motherwort, lemongrass, and mugwort all carry pregnancy concerns — the safety data advises against use during pregnancy because they've been traditionally used to stimulate the uterus and may pose uterine-related risks. Lemon balm lacks enough reliable data for pregnancy; talk with your doctor before using it if you're pregnant or planning to become pregnant.

Breastfeeding safety isn't well studied for any of these ingredients; check with your pharmacist or doctor if you're nursing. Side effects reported with these extracts are generally mild when used orally.

Motherwort may cause diarrhea or stomach irritation. Mugwort can trigger allergic reactions (asthma, rash, even anaphylaxis) in people sensitive to ragweed.

Lemon balm occasionally causes dizziness or sedation, though it doesn't seem to happen more often than with placebo. All these herbal extracts have limited human safety data overall, especially at higher or long-term doses.

Side effects, ingredient by ingredient Motherwort Linden Lemongrass Mugwort Lemon Balm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Motherwort, Lemon Balm, Linden, Lemongrass.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 860 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Joy Tonic, check with your pharmacist if you use CNS depressants (sleeping pills, anti-anxiety drugs, opioids, or anything that makes you drowsy) — motherwort and lemon balm may intensify drowsiness at a Moderate level. If you take lithium for mood disorders, a Moderate interaction with linden may affect your dose.

Medications metabolized by liver enzyme CYP3A4 (many cholesterol and blood pressure drugs) and glucuronidated drugs may have their levels changed by lemongrass at a Moderate level. If you're on thyroid hormone replacement, lemon balm may theoretically interfere at a Moderate level.

Use the search tool on this page to verify your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Joy Tonic is a herbal nervine blend that may interest you if you're exploring traditional botanical support for mood or stress, though the clinical evidence for its specific use is sparse. If you take any prescription medications — especially sedating drugs, lithium, thyroid medication, or cholesterol drugs — run them through our checker before starting.

Pregnant or breastfeeding folks should talk with their pharmacist before use. It's worth a conversation with us to make sure it fits your personal health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Joy Tonic, straight from the product label.

Brand Urban Moonshine
Barcode (UPC) 851588002418
Net contents 8.4 fl. Oz.; 250 mL
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50606
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Joy Tonic by Urban Moonshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
5 mL
Servings per container
50
UPC/BARCODE
851588002418
IngredientAmount% DV
Proprietary Herbal Extract Blend (Herb/Botanical)5 mL--
org. Rose petal extract0 NP--
organic Motherwort leaf and flower extract0 NP--
org. Linden leaf and flower extract0 NP--
org. Lemongrass extract0 NP--
org. Mugwort leaf extract0 NP--
org. Lemon Balm leaf extract0 NP--

Other ingredients: Water, organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

03

Suggested/Recommended/Usage/Directions

Suggested Use: Enjoy 5 ml (1 tsp) 1-3 times a day. Dispense serving and top off with water. Mindfully let go of tension, making room for love, joy and gratitude.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

45-50% alcohol.

General Statements

50 servings per bottle

VOF Certified

The aromatic herbs in our Joy Tonic are traditionally used to support the nervous system, uplift the spirit, gladden the heart, and relieve occasional sleeplessness.* Choose Joy! -Jovial King, Founder

Herbal Apothecary

Calm, Peaceful, Inspired*

Stress support

Fast acting for occasional anxiety

FDA Statement of Identity

Herbal Supplement

Formulation

Gluten Free.

Precautions

Not to be used during pregnancy.

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Joy Tonic by Urban Moonshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Joy Tonic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Joy Tonic by Urban Moonshine

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Extract Blend (Herb/Botanical)

5 mL per serving

Other (inactive) ingredients: Water, Organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Joy Tonic by Urban Moonshine Drug Interactions

Want to check YOUR meds against Joy Tonic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
859Drugs
859 Moderate

Ingredients driving the most interactions

org. Lemongrass extract 708
org. Lemon Balm leaf extract 264
organic Motherwort leaf and flower extract 248
org. Linden leaf and flower extract 1

Individual Drug Interactions

The ingredients in Joy Tonic interact with 859 drugs. Click any drug to see the details.

4 of the 6 ingredients in Joy Tonic interact with drugs. Each result below shows which ingredient is responsible. org. Lemongrass extract org. Lemon Balm leaf extract organic Motherwort leaf and flower extract org. Linden leaf and flower extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Joy Tonic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

org. Lemongrass extract3 drug types · 708 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Animal research shows that lemongrass and its constituent citral inhibit CYP3A4.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, lemongrass might increase the clearance and decrease the levels of glucuronidated drugs.
Animal research shows that lemongrass and its constituent citral induce uridine diphosphoglucuronosyl transferase (UGT), the major phase 2 enzyme that is responsible for glucuronidation.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, lemongrass might increase the effects and adverse effects of pentobarbital.
Animal research shows that high doses of lemongrass essential oil increases sleep time and decreases time to fall asleep in animals administered pentobarbital.

Likelihood Possible Evidence D
org. Lemongrass extract full monograph & interactions

org. Lemon Balm leaf extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
org. Lemon Balm leaf extract full monograph & interactions

organic Motherwort leaf and flower extract1 drug type · 248 drugs

Cns Depressants

Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Motherwort has been reported to cause CNS depression and sedation.

Likelihood Possible Evidence D
organic Motherwort leaf and flower extract full monograph & interactions

org. Linden leaf and flower extract1 drug type · 1 drug

Lithium

Theoretically, due to its potential diuretic effects, linden might increase the effects and adverse effects of lithium.
Linden is thought to have diuretic properties. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
org. Linden leaf and flower extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Joy Tonic, from the product label.

Urban Moonshine

See all Urban Moonshine products
Name
Urban Moonshine
Street Address
255 S. Champlain St.
City
Burlington
State
VT
ZipCode
05401
Phone Number
802-428-4707
Web Address
urbanmoonshine.com
Pharmacist Counseling Corner

Joy Tonic by Urban Moonshine: Common Questions

Does Joy Tonic by Urban Moonshine interact with any medications?
Yes. Based on its ingredients, Joy Tonic has a known interaction with 859 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Joy Tonic contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Joy Tonic if I'm pregnant or breastfeeding?
Our data advises against it during pregnancy — motherwort, lemongrass, and mugwort have traditionally been used to stimulate the uterus and may carry uterine-related risks. Lemon balm doesn't have enough reliable safety data for pregnancy; check with your doctor. For breastfeeding, safety information for these herbs is limited, so talk with your pharmacist or doctor before use.
What is motherwort supposed to do in this blend?
Motherwort is possibly effective for bleeding according to our data. It's also used traditionally as a nervine — a plant thought to calm the nervous system — though evidence for anxiety relief is insufficient to rate. In traditional herbalism, it's been associated with heart and uterine health.
Does lemon balm actually help with stress and mood?
Yes — lemon balm is rated as possibly effective for stress and depression in our data. It's one of the better-researched ingredients in this blend, though the strength of evidence is moderate rather than definitive.
Could this product interact with my blood pressure or cholesterol medication?
Lemongrass in this blend may interact with medications metabolized by liver enzyme CYP3A4, which includes many cholesterol and blood pressure drugs — it could change how quickly your body clears them. Use the checker on this page with your exact medication names, or ask your pharmacist to confirm.
I'm allergic to ragweed. Should I avoid this product?
Mugwort is in the ragweed family, and people sensitive to ragweed have reported allergic reactions to mugwort — including asthma, rash, and even anaphylaxis. If you have a ragweed allergy, talk with your pharmacist before trying this product.
What side effects might I notice?
Most herbal side effects here are mild. Motherwort may cause diarrhea or stomach irritation. Lemon balm can occasionally cause dizziness or sedation. Mugwort poses an allergy risk if you're sensitive. Overall, these extracts are generally well tolerated in the short term, though long-term safety data are limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Joy Tonic is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Joy Tonic label
Go deeper

The Full Monographs Behind Joy Tonic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Motherwort

Interacts with 248 drugs

Motherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but solid human evidence is very limited. It should be avo...

Read the full Motherwort monograph → Herb & supplement monograph

Linden

Interacts with 1 drug

Linden (also called lime flower) is a traditional herbal tea long used to calm nerves, ease cold symptoms, and support restful sleep. Strong human evidence for these uses is lacking, but the...

Read the full Linden monograph → Herb & supplement monograph

Lemongrass

Interacts with 708 drugs

Lemongrass is a fragrant tropical grass widely used as a cooking herb, a tea, and an aromatherapy oil. It is generally considered safe in the small amounts used in food, but most of its clai...

Read the full Lemongrass monograph → Herb & supplement monograph

Mugwort

Mugwort is a traditional herb used for digestion, menstrual issues, and sleep, but there is very little high-quality human research to confirm these uses. It is closely related to ragweed an...

Read the full Mugwort monograph → Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

Joy Tonic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Motherwort 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Wojtyniak K, Szymanski M, Matlawska I. Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology. Phytother Res 2013;27(8):1115-20.
  5. Xia WT, Zhou H, Wang Y, et al. Motherwort injection in preventing post-abortion hemorrhage after induced abortion: A multi-center, prospective, randomized controlled trial. Explore (NY). 2019. pii: S1550-8307(19)30447-1. PubMed
  6. Cao Shan DOSOGC, Zhang W, Zhao Z, et al. Post-marketing safety surveillance and reevaluation of Motherwort injection: A clinical study of 10 094 cases. J Tradit Chin Med. 2018 Aug;38(4):625-635. DOI

See these in context on the Motherwort monograph →

Linden 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

See these in context on the Linden monograph →

Lemongrass 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Li CC, Yu HF, Chang CH, Liu YT, Yao HT. Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats. J Food Drug Anal 2018;26(1):432-8. PubMed

See these in context on the Lemongrass monograph →

Mugwort 7 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Borghesan F, Mistrello G, Amato S, Giuffrida MG, Villalta D, Asero R. Mugwort-fennel-allergy-syndrome associated with sensitization to an allergen homologous to Api g 5. Eur Ann Allergy Clin Immunol. 2013;45(4):130-7.
  4. Kim SH, Lee SM, Park HW, et al. Chinese bellflower root anaphylaxis: IgE-binding components and cross-reactivity with mugwort and birch. Korean J Intern Med. 2009;24(3):279-82. PubMed
  5. Silva R, Lopes C, Castro E, et al. Anaphylaxis to mango fruit and crossreactivity with Artemisia vulgaris pollen. J Investig Allergol Clin Immunol. 2009;19(5):420-2.
  6. Rodrigues-Alves R, Pregal A, Pereira-Santos MC, et al. Anaphylaxis to pine nut: cross-reactivity to Artemisia vulgaris? Allergol Immunopathol (Madr). 2008;36(2):113-6. PubMed
  7. Di Lorenzo C, Ferretti F, Moro E, et al. Identification and quantification of thujone in a case of poisoning due to repeated ingestion of an infusion of Artemisia vulgaris L. J Food Sci. 2018;83(8):2257-2264.

See these in context on the Mugwort monograph →

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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