Drug & supplement interaction

Stem Cell Therapy + Chloroprocaine

Chloroprocaine brand names: Nesacaine, Nescaine-MPF.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Stem Cell Therapy and Chloroprocaine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Stem Cell Therapy and Chloroprocaine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Chloroprocaine and Stem Cell Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Stem Cell Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Stem Cell Therapy at all — not against Chloroprocaine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Stem Cell Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Stem Cell Therapy safety at a glance

Stem Cell Therapy overall Use caution Proven uses exist, but most marketed stem cell treatments are unproven and can carry serious risks.

Pregnancy Avoid Unproven stem cell treatments should be avoided during pregnancy unless medically necessary and supervised by specialists.

Breastfeeding Avoid Avoid elective stem cell procedures while breastfeeding; safety has not been established.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Chloroprocaine and Stem Cell Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

No Interaction Found — But Data Suggests Stem Cell Therapy and Chloroprocaine May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Stem Cell Therapy while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do.

Back pain Additional detail
Stem Cell Therapy
“Injected direct-to-consumer stem cell preparations have been associated with the development of various cancerous lesions. In a case report, a 66-year-old man received intrathecal infusions of mesenchymal, embryonic, and fetal neural stem cells for ischemic stroke recovery at commercial stem-cell clinics, which resulted in glioproliferative lesions in the spinal cord causing lower back pain, paraplegia, and urinary i…”

Stem Cell Therapy · Natural Medicines adverse-effect record, reported in back pain.
2 sources cited

99543. Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018;7(9):676-685. PubMed

99545. Berkowitz AL, Miller MB, Mir SA, et al. Glioproliferative Lesion of the Spinal Cord as a Complication of "Stem-Cell Tourism". N Engl J Med. 2016 Jul 14;375(2):196-8. PubMed
Chloroprocaine

Listed in the ADVERSE REACTIONS section of the FDA label for Chloroprocaine. Read the label on DailyMed ›

Reported for Stem Cell Therapy but not commonly for Chloroprocaine: a severe skin reaction, blood clots, a heart attack and loss of bladder control.

Effects for Chloroprocaine come from the ADVERSE REACTIONS section of its FDA label; effects for Stem Cell Therapy come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Chloroprocaine

This page covers Stem Cell Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Chloroprocaine page lists 5 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Fever Bark (major), Cannabis (moderate), Cowhage (moderate), Datura Wrightii (moderate) and Delta-9-tetrahydrocannabinol (thc) (moderate).

By severity: 1 major · 4 moderate.

From our pharmacist’s overview on the Chloroprocaine page

“Fever bark is the ingredient I would flag first for anyone scheduled to receive chloroprocaine (Nesacaine), a local anesthetic injected for epidurals and other numbing procedures. It holds the list's lone major rating because its constituent reserpine has been linked to unstable blood pressure and heart rhythm under anesthesia.”

Reviewed by 2 · Jul 18, 2026

Open the Chloroprocaine interaction page

How much people look this up

Where Stem Cell Therapy and Chloroprocaine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Stem Cell Therapy

Top half

#720 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Chloroprocaine

Steady interest

#2,039 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Stem Cell Therapy reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Stem Cell Therapy and Chloroprocaine records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Treatment approach

About Stem Cell Therapy

What is Stem Cell Therapy?

Joint and arthritis pain
Sports and orthopedic injuries
Anti-aging and wellness
Blood and immune disorders (proven medical uses)
Neurological conditions (experimental)

Stem cell therapy is a medical treatment, not a dietary supplement or herb. While some forms—like bone marrow transplants for blood cancers—are well-established and FDA-approved, most clinics offering stem cell injections for joints, aging, or chronic disease are selling unproven, sometimes risky treatments. Talk to a qualified doctor and be very cautious of clinics making big promises.

Stem cells (from bone marrow, blood, fat tissue, or umbilical cord) · Clinic-administered injections or infusions of cells

An interaction check asks whether these two react with each other — it does not ask whether Stem Cell Therapy is a good idea for someone in your situation. Here is what our Stem Cell Therapy record says about it on its own.

Stem Cell Therapy: dosing

There is no standard over-the-counter dose for stem cell therapy, because it is a medical procedure, not a supplement you buy and take at home. The type of cells, how they are prepared, and how they are given vary widely by treatment and clinic.For approved uses like transplants, dosing is carefully calculated by specialists based on the patient and condition. For unproven clinic treatments, there is no agreed-upon dose, and that lack of standardization is one reason these treatments are hard to judge for safety.Never accept a stem cell treatment based only on marketing.

From our Stem Cell Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Stem Cell Therapy monograph & all interactions

Medication

About Chloroprocaine

What Is Chloroprocaine Used For?

Brand names: Nesacaine, Nescaine-MPF

Chloroprocaine injection is used to produce local anesthesia — numbing — for a range of medical and surgical procedures. The specific uses depend on the product and concentration.

Nesacaine 1% and 2% (multidose vials with preservative) are approved for infiltration (numbing tissue directly) and peripheral nerve block only — not for epidural use. Nesacaine-MPF 2% and 3% (preservative-free, single-dose vials) are approved for infiltration, peripheral nerve block, and central nerve block, including lumbar and caudal epidural anesthesia. Chloroprocaine hydrochloride injection 2% and 3% (single-dose, preservative-free vials) are similarly approved for infiltration, peripheral and central nerve block, including lumbar and caudal epidural blocks. Iheezo, the ophthalmic gel, is used to numb the surface of the eye before procedures on or near the eye.

See full Chloroprocaine drug information

Keep checking

Other Drugs & Stem Cell Therapy

Browse every other medication we’ve checked against Stem Cell Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Stem Cell Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Stem Cell Therapy list.

See the full Stem Cell Therapy interactions page

See every supplement checked against Chloroprocaine, ranked by severity

Evidence & sources

Stem Cell Therapy References

The 26 references that drive our Stem Cell Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Ansari ZA, Kuriyan AE, Albini TA. Unproven stem cell therapy for macular degeneration. Oncotarget. 2017;8(53):90636-90637. PubMed
Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018;7(9):676-685. PubMed
Berkowitz AL, Miller MB, Mir SA, et al. Glioproliferative Lesion of the Spinal Cord as a Complication of "Stem-Cell Tourism". N Engl J Med. 2016 Jul 14;375(2):196-8. PubMed
Kuriyan AE, Albini TA, Townsend JH, et al. Vision Loss after Intravitreal Injection of Autologous "Stem Cells" for AMD. N Engl J Med. 2017;376(11):1047-1053. PubMed
Perkins KM, Spoto S, Rankin DA, et al. Notes from the Field: Infections After Receipt of Bacterially Contaminated Umbilical Cord Blood-Derived Stem Cell Products for Other Than Hematopoietic or Immunologic Reconstitution - United States, 2018. MMWR Morb M
Iijima H, Isho T, Kuroki, Takahashi, Aoyama. Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation. NPJ Regen Med. 2018;3:15. PubMed
Sanapati J, Manchikanti L, Atluri S, et al. Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis. Pain Physician. 2018;21(6):515-540. DOI
Rocco M, Juri C. Is treatment with stem cells effective in Parkinson's disease? Medwave. 2018;18(5):e7242. PubMed
Shah R, Latham SB, Khan SA, Shahreyar M, Hwang I, Jovin IS. A comprehensive meta-analysis of stem cell therapy for chronic angina. Clin Cardiol. 2018;41(4):525-531. PubMed
Guo J, Dardik A, Fang K, Huang R, Gu Y. Meta-analysis on the treatment of diabetic foot ulcers with autologous stem cells. Stem Cell Res Ther. 2017;8(1):228. PubMed
Nagpal A, Choy FC, Howell S, et al. Safety and effectiveness of stem cell therapies in early-phase clinical trials in stroke: a systematic review and meta-analysis. Stem Cell Res Ther. 2017;8(1):191. PubMed
Qiu Y, Li MY, Feng T, et al. Systematic review with meta-analysis: the efficacy and safety of stem cell therapy for Crohn's disease. Stem Cell Res Ther. 2017;8(1):136. PubMed
Sormani MP, Muraro PA, Schiavetti I, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: A meta-analysis. Neurology. 2017;88(22):2115-2122. PubMed
Gao W, Chen D, Liu G, Ran X. Autologous stem cell therapy for peripheral arterial disease: a systematic review and meta-analysis of randomized controlled trials. Stem Cell Res Ther. 2019;10(1):140. PubMed
Fisher SA, Doree C, Mathur A, Taggart DP, Martin-Rendon E. Stem cell therapy for chronic ischaemic heart disease and congestive heart failure. Cochrane Database Syst Rev. 2016;12:CD007888. PubMed
Novak I, Walker K, Hunt RW, Wallace EM, Fahey M, Badawi N. Concise Review: Stem Cell Interventions for People With Cerebral Palsy: Systematic Review With Meta-Analysis. Stem Cells Transl Med. 2016;5(8):1014-25. PubMed
Zahid MF, Murad MH, Litzow MR, et al. Venous thromboembolism following hematopoietic stem cell transplantation-a systematic review and meta-analysis. Ann Hematol. 2016;95(9):1457-64. PubMed
El-Badawy A, El-Badri N. Clinical Efficacy of Stem Cell Therapy for Diabetes Mellitus: A Meta-Analysis. PLoS One. 2016;11(4):e0151938. PubMed
Kim G, Eom YW, Baik SK, et al. Therapeutic Effects of Mesenchymal Stem Cells for Patients with Chronic Liver Diseases: Systematic Review and Meta-analysis. J Korean Med Sci. 2015;30(10):1405-15. PubMed
Fisher SA, Zhang H, Doree C, Mathur A, Martin-Rendon E. Stem cell treatment for acute myocardial infarction. Cochrane Database Syst Rev. 2015;(9):CD006536. PubMed
Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis Rheumatol. 2020 Feb;72(2):220-33. PubMed
Skeen M, Eksteen C, Pepper M. Stem cell tourism and spinal cord injury in South Africa. S Afr Med J. 2019 Sep 10;109(8b):17-23. PubMed
Madhavan AA, Summerfield D, Hunt CH, et al. Polyclonal lymphocytic infiltrate with arachnoiditis resulting from intrathecal stem cell transplantation. Neuroradiol J. 2020 Apr;33(2):174-178. PubMed
Richardson E, Project Director. Harms linked to unapproved stem cell interventions highlight need for greater FDA enforcement. The Pew Charitable Trusts Brief. June 2021. Available at: https://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2021/0
Appelt PA, Comella K, de Souza LAPS, Luvizutto GJ. Effect of stem cell treatment on functional recovery of spinocerebellar ataxia: systematic review and meta-analysis. Cerebellum Ataxias. 2021 Feb 25;8(1):8. PubMed
Hinkle JW, Mahmoudzadeh R, Kuriyan AE. Cell-based therapies for retinal diseases: a review of clinical trials and direct to consumer "cell therapy" clinics. Stem Cell Res Ther. 2021 Oct 11;12(1):538. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Stem Cell Therapy While Taking Chloroprocaine: Common Questions

Is it safe to have Stem Cell Therapy while taking Chloroprocaine?

We do not list a known interaction between Stem Cell Therapy and Chloroprocaine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Stem Cell Therapy and Chloroprocaine have any of the same side effects?

Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Does Chloroprocaine interact with any supplements?

Yes. Chloroprocaine has documented interactions with 5 supplements in our database — Stem Cell Therapy is not one of them. The Chloroprocaine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Stem Cell Therapy monograph Uses, safety profile, and every drug interaction in one place Chloroprocaine drug information The full plain-English guide to this medication Chloroprocaine supplement interactions Every supplement checked against Chloroprocaine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 26 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Chloroprocaine and Stem Cell Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.