Drug & supplement interaction

Stenabolic + Loperamide, Simethicone

Loperamide, Simethicone brand name: Imodium Advanced.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Stenabolic and Loperamide, Simethicone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Loperamide, Simethicone states a food rule worth keeping to.

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Interaction report

Stenabolic and Loperamide, Simethicone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Loperamide, Simethicone and Stenabolic in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Stenabolic at all — not against Loperamide, Simethicone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Stenabolic safety at a glance

Stenabolic overall Avoid Stenabolic is an untested research chemical with no human safety data and is not legal to sell as a supplement.
Pregnancy Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Loperamide, Simethicone and Stenabolic? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Special populations

Stenabolic in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Loperamide, Simethicone Products Have a Food Rule — Stenabolic Should Not Break It

At least one FDA label for a product containing Loperamide, Simethicone says to take it on an empty stomach. Most supplements — Stenabolic included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Loperamide, Simethicone on its own and move Stenabolic to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Loperamide, Simethicone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Directions drink plenty of clear fluids to help prevent dehydration caused by diarrhea take only on an empty stomach (1 hour before or 2 hours after a meal) take with a full (8 oz.) glass of water find right dose on chart below.

From the Dosage and Administration section of the FDA label we read for Loperamide, Simethicone — where that label names a specific product, the instruction is that product's.

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Loperamide, Simethicone

This page covers Stenabolic only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Loperamide, Simethicone page lists 82 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), St. John's Wort (major) and Angel's Trumpet (moderate).

By severity: 4 major · 59 moderate · 19 minor.

From our pharmacist’s overview on the Loperamide, Simethicone page

“Imodium Advanced combines loperamide, an anti-diarrheal opioid that normally stays out of the brain thanks to a transporter called P-glycoprotein, with simethicone for gas, and I treat its interaction list with more respect than most over-the-counter medicines warrant. Thirty-seven of the 82 interacting ingredients on file affect that…”

Reviewed by 2 · Jul 18, 2026

Open the Loperamide, Simethicone interaction page

One more smart check

Taking Stenabolic as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Stenabolic, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Stenabolic. Even though Stenabolic itself has no known interaction with Loperamide, Simethicone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Stenabolic and Loperamide, Simethicone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Stenabolic
Top half

#606 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Loperamide, Simethicone
Top half

#832 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Stenabolic reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Stenabolic and Loperamide, Simethicone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Stenabolic

What is Stenabolic?

  • Endurance and stamina
  • Fat loss
  • Bodybuilding and athletic performance
  • Boosting metabolism

Stenabolic (also called SR9009) is an experimental research chemical, not a true dietary supplement, herb, or approved drug. It is sold online for fat loss and endurance, but it has never been tested for safety or effectiveness in humans, and it is banned in sports. Because the risks are unknown and product quality is unreliable, we do not recommend using it.

Synthetic compound (not from a plant) · Capsules, liquid solutions, powders

An interaction check asks whether these two react with each other — it does not ask whether Stenabolic is a good idea for someone in your situation. Here is what our Stenabolic record says about it on its own.

Stenabolic: dosing

There is no established or approved dose for Stenabolic because it has never been tested in proper human studies. Doses suggested on websites and forums are not based on safety research.We cannot recommend a dose. Given the lack of safety data, the risk of contaminated products, and its banned status in sports, the safest choice is not to use it at all.

From our Stenabolic monograph — the full record covers uses, side effects and every documented interaction.

Read the full Stenabolic monograph & all interactions
Keep checking

Other Drugs & Stenabolic

Browse every other medication we’ve checked against Stenabolic — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Stenabolic References

The 1 references that drive our Stenabolic monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Stenabolic and Loperamide, Simethicone Together: Common Questions

Is it safe to take Stenabolic with Loperamide, Simethicone?
We do not list a known interaction between Stenabolic and Loperamide, Simethicone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Stenabolic and Loperamide, Simethicone at the same time of day?
At least one FDA label for a product containing Loperamide, Simethicone says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Loperamide, Simethicone on its own and move Stenabolic to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Loperamide, Simethicone interact with any supplements?
Yes. Loperamide, Simethicone has documented interactions with 82 supplements in our database — Stenabolic is not one of them. The Loperamide, Simethicone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Loperamide, Simethicone and Stenabolic?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.