Herb & supplement monograph

Stenabolic Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Stenabolic

0 medications have a known interaction with Stenabolic, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Stenabolic. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Stenabolic combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Stenabolic: Uses, Safety & Side Effects

The bottom line

Stenabolic (also called SR9009) is an experimental research chemical, not a true dietary supplement, herb, or approved drug. It is sold online for fat loss and endurance, but it has never been tested for safety or effectiveness in humans, and it is banned in sports. Because the risks are unknown and product quality is unreliable, we do not recommend using it.

Part used
Synthetic compound (not from a plant)
Common forms
Capsules, liquid solutions, powders
People commonly use it for
  • Endurance and stamina
  • Fat loss
  • Bodybuilding and athletic performance
  • Boosting metabolism

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallBest avoided

Stenabolic is an untested research chemical with no human safety data and is not legal to sell as a supplement.

PregnancyPossibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Av...

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Av...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Stenabolic, often sold under the code name SR9009, is a synthetic chemical made in a laboratory. It is not an herb, plant extract, or vitamin, even though it is often sold alongside supplements online.

It was first created as a research tool to study the body's internal clock and metabolism. It has never been approved as a medicine or as a dietary supplement by the U.S. Food and Drug Administration (FDA) or any other major health authority.

Despite this, Stenabolic is marketed to bodybuilders and athletes for fat loss and improved endurance. It is frequently grouped with SARMs (selective androgen receptor modulators), though it works differently. Products sold online are not regulated, so what is in the bottle is often unknown.

How it works

Stenabolic is described as a REV-ERB agonist. REV-ERB is a protein in the body that helps control the natural daily rhythm (circadian clock) and influences how cells handle fat, sugar, and energy.

In laboratory and animal studies, activating REV-ERB appeared to change how the body burns fat and uses energy, and it affected muscle and exercise capacity in mice. Researchers think this is how it might, in theory, affect metabolism and endurance.

It is important to stress that these mechanisms are based on animal and test-tube research. We do not know if Stenabolic behaves the same way in the human body, what doses would matter, or what long-term effects it might have.

Effectiveness

Does Stenabolic work?

Evidence overview · 3 uses evaluated
3 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Stenabolic, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 3 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Athletic performance
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral stenabolic for athletic performance, there is insufficient reliable information about the clinical effects of stenabolic for this purpose.

Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral stenabolic for diabetes, there is insufficient reliable information about the clinical effects of stenabolic for this condition.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there is interest in using oral stenabolic for obesity, there is insufficient reliable information about the clinical effects of stenabolic for this condition.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

The honest answer is that the safety of Stenabolic in humans is unknown. There are no human trials studying its short- or long-term effects, so no one can say it is safe.

Because it is sold as an unregulated research chemical, products may be mislabeled, contaminated, or contain different amounts than stated. Investigations of these online products have repeatedly found inaccurate ingredients.

Stenabolic is banned by the World Anti-Doping Agency (WADA), so athletes who use it risk failing drug tests and losing eligibility. Pregnant or breastfeeding people should not use it because there is zero safety data. People with any medical condition, and anyone under 18, should also avoid it. Always talk to a pharmacist or doctor before considering any product like this.

Side effects

Because Stenabolic has not been studied in humans, its true side effect profile is unknown. Anyone using it is essentially experimenting on themselves.

Possible concerns include effects on sleep and the body's natural rhythm, changes in energy or mood, and unknown effects on the liver, heart, and hormones. Because products may be contaminated, additional harm could come from unlisted ingredients.

If you have taken a product containing Stenabolic and feel unwell — for example chest pain, severe fatigue, yellowing of the skin or eyes, or other worrying symptoms — stop using it and seek medical care right away.

Dosing

There is no established or approved dose for Stenabolic because it has never been tested in proper human studies. Doses suggested on websites and forums are not based on safety research.

We cannot recommend a dose. Given the lack of safety data, the risk of contaminated products, and its banned status in sports, the safest choice is not to use it at all. If you are looking for help with fat loss or athletic performance, speak with a pharmacist or doctor about safe, evidence-based options.

Pregnancy & Breastfeeding

Stenabolic & Pregnancy

Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

Stenabolic & Breastfeeding

Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Stenabolic monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Stenabolic: Common Questions

What is Stenabolic used for, and does it work?
People use Stenabolic for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Stenabolic interact with prescription medications?
We do not currently list any known drug interactions for Stenabolic. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Stenabolic interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Stenabolic with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Stenabolic interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Stenabolic a SARM?
No, not technically. Stenabolic (SR9009) is often sold and grouped with SARMs, but it works on a different target called REV-ERB. Like SARMs, it is an unapproved research chemical, not a legal dietary supplement.
Is Stenabolic safe to take?
Its safety in humans is unknown because it has never been properly tested in people. Combined with the risk of contaminated or mislabeled products, we do not consider it safe to use.
Does Stenabolic really help you lose fat or boost endurance?
The fat-loss and endurance claims come from mouse and laboratory studies, not human trials. There is no reliable evidence that it works in people, and it may be poorly absorbed when taken by mouth.
Can athletes use Stenabolic?
No. Stenabolic is banned by the World Anti-Doping Agency, so using it can lead to a failed drug test and loss of eligibility to compete.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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