Drug & supplement interaction

Stenabolic + Phendimetrazine

Phendimetrazine brand names: Plegine, Metra, Weightrol.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Stenabolic and Phendimetrazine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Stenabolic and Phendimetrazine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Phendimetrazine and Stenabolic in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Stenabolic at all — not against Phendimetrazine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Stenabolic safety at a glance

Stenabolic overall Avoid Stenabolic is an untested research chemical with no human safety data and is not legal to sell as a supplement.
Pregnancy Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Phendimetrazine and Stenabolic? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Phendimetrazine’s Own FDA Label Lists

This is not an interaction — none of it involves Stenabolic. These are the most notable effects listed in the ADVERSE REACTIONS section of Phendimetrazine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Pain or burning when passing urine Worth acting on
  • Raised blood pressure Worth acting on
  • Tremor or shakiness
  • Flushing
  • Sweating
  • A fast or pounding heartbeat
  • Anxiety or restlessness
  • Trouble sleeping
  • Constipation
  • Stomach pain

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Phendimetrazine. Read the label on DailyMed › Stenabolic’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Stenabolic side to compare — that is a limit of the record, not a statement that Stenabolic has no side effects.

Special populations

Stenabolic in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Phendimetrazine Is Prescribed For, and What Stenabolic Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Phendimetrazine is a prescription medicine with approved uses on its FDA label. Stenabolic is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Phendimetrazine is prescribed for: Phendimetrazine tartrate is used to help manage exogenous obesity (excess body weight from outside causes like diet and lifestyle) as a short-term addition to a calorie-restricted diet. It is intended for adults with a BMI of 30 or higher, or a BMI of 27 or higher when other risk factors — such as high blood pressure, diabetes, or high cholesterol — are also present. It is approved for use as monotherapy only, meaning it must not be combined with other weight-loss drugs or stimulants. Both the tablet form and the extended-release capsule form are approved for this purpose.

Read the rest of what Phendimetrazine is prescribed for

This medication is meant to be used for only a few weeks as part of a broader weight-management plan.

Stenabolic has been studied for:

  • Diabetes studied, not established Stenabolic has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Stenabolic for diabetes

    Although there is interest in using oral stenabolic for diabetes, there is insufficient reliable information about the clinical effects of stenabolic for this condition.

  • Obesity studied, not established Stenabolic has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Stenabolic for obesity

    Although there is interest in using oral stenabolic for obesity, there is insufficient reliable information about the clinical effects of stenabolic for this condition.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Phendimetrazine on your own; if you are taking Stenabolic for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Phendimetrazine

This page covers Stenabolic only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Phendimetrazine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Phendimetrazine page

“Of the 17 supplements on file for phendimetrazine, an appetite-suppressant stimulant prescribed short term for weight loss, activated charcoal is the one that demands real caution. Charcoal binds medications in the gut and can sharply cut how much of a drug your body absorbs, leaving you with less appetite control than your prescriptio…”

Reviewed by 2 · Jul 18, 2026

Open the Phendimetrazine interaction page

One more smart check

Taking Stenabolic as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Stenabolic, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Stenabolic. Even though Stenabolic itself has no known interaction with Phendimetrazine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Stenabolic and Phendimetrazine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Stenabolic
Steady interest

#840 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Phendimetrazine
Top 25%

#353 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Stenabolic reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Stenabolic and Phendimetrazine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Stenabolic

What is Stenabolic?

  • Endurance and stamina
  • Fat loss
  • Bodybuilding and athletic performance
  • Boosting metabolism

Stenabolic (also called SR9009) is an experimental research chemical, not a true dietary supplement, herb, or approved drug. It is sold online for fat loss and endurance, but it has never been tested for safety or effectiveness in humans, and it is banned in sports. Because the risks are unknown and product quality is unreliable, we do not recommend using it.

Synthetic compound (not from a plant) · Capsules, liquid solutions, powders

An interaction check asks whether these two react with each other — it does not ask whether Stenabolic is a good idea for someone in your situation. Here is what our Stenabolic record says about it on its own.

Stenabolic: dosing

There is no established or approved dose for Stenabolic because it has never been tested in proper human studies. Doses suggested on websites and forums are not based on safety research.We cannot recommend a dose. Given the lack of safety data, the risk of contaminated products, and its banned status in sports, the safest choice is not to use it at all.

From our Stenabolic monograph — the full record covers uses, side effects and every documented interaction.

Read the full Stenabolic monograph & all interactions
Medication

About Phendimetrazine

What Is Phendimetrazine Used For?

Brand names: Plegine, Metra, Weightrol

Phendimetrazine tartrate is used to help manage exogenous obesity (excess body weight from outside causes like diet and lifestyle) as a short-term addition to a calorie-restricted diet. It is intended for adults with a BMI of 30 or higher, or a BMI of 27 or higher when other risk factors — such as high blood pressure, diabetes, or high cholesterol — are also present.

It is approved for use as monotherapy only, meaning it must not be combined with other weight-loss drugs or stimulants. Both the tablet form and the extended-release capsule form are approved for this purpose. This medication is meant to be used for only a few weeks as part of a broader weight-management plan.

See full Phendimetrazine drug information
Keep checking

Other Drugs & Stenabolic

Browse every other medication we’ve checked against Stenabolic — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Stenabolic References

The 1 references that drive our Stenabolic monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Stenabolic and Phendimetrazine Together: Common Questions

Is it safe to take Stenabolic with Phendimetrazine?
We do not list a known interaction between Stenabolic and Phendimetrazine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Stenabolic and Phendimetrazine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Stenabolic in each. That is a conversation for your prescriber, especially if Phendimetrazine is being adjusted to a target.
Does Phendimetrazine interact with any supplements?
Yes. Phendimetrazine has documented interactions with 17 supplements in our database — Stenabolic is not one of them. The Phendimetrazine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Phendimetrazine and Stenabolic?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.