Drug & supplement interaction

Stenabolic + Upadacitinib Hemihydrate

Upadacitinib Hemihydrate brand name: Rinvoq.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Stenabolic and Upadacitinib Hemihydrate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Stenabolic and Upadacitinib Hemihydrate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Upadacitinib Hemihydrate and Stenabolic in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Stenabolic at all — not against Upadacitinib Hemihydrate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Stenabolic safety at a glance

Stenabolic overall Avoid Stenabolic is an untested research chemical with no human safety data and is not legal to sell as a supplement.
Pregnancy Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Upadacitinib Hemihydrate and Stenabolic? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Upadacitinib Hemihydrate’s Own FDA Label Lists

This is not an interaction — none of it involves Stenabolic. These are the most notable effects listed in the ADVERSE REACTIONS section of Upadacitinib Hemihydrate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Severe muscle breakdown Worth acting on
  • Low blood sugar Worth acting on
  • Blood clots Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Acne
  • Weight gain

Showing the 10 most notable of 22 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Upadacitinib Hemihydrate. Read the label on DailyMed › Stenabolic’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Stenabolic side to compare — that is a limit of the record, not a statement that Stenabolic has no side effects.

Special populations

Stenabolic in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Upadacitinib Hemihydrate

This page covers Stenabolic only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Upadacitinib Hemihydrate page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Upadacitinib Hemihydrate page

“Grapefruit is the pairing I would want anyone on Rinvoq (upadacitinib) to know about first. The drug is cleared by a liver enzyme called CYP3A4, and grapefruit blocks that enzyme, letting blood levels climb, which matters for a medicine that already dials down the immune system.”

Reviewed by 2 · Jul 18, 2026

Open the Upadacitinib Hemihydrate interaction page

One more smart check

Taking Stenabolic as Part of a Dietary Supplement Product? Check It for Interactions

We hold 8 real supplement products containing Stenabolic, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Stenabolic. Even though Stenabolic itself has no known interaction with Upadacitinib Hemihydrate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Stenabolic and Upadacitinib Hemihydrate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Stenabolic
Top half

#640 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Upadacitinib Hemihydrate
Steady interest

#1,930 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Stenabolic reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Stenabolic and Upadacitinib Hemihydrate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Stenabolic

What is Stenabolic?

  • Endurance and stamina
  • Fat loss
  • Bodybuilding and athletic performance
  • Boosting metabolism

Stenabolic (also called SR9009) is an experimental research chemical, not a true dietary supplement, herb, or approved drug. It is sold online for fat loss and endurance, but it has never been tested for safety or effectiveness in humans, and it is banned in sports. Because the risks are unknown and product quality is unreliable, we do not recommend using it.

Synthetic compound (not from a plant) · Capsules, liquid solutions, powders

An interaction check asks whether these two react with each other — it does not ask whether Stenabolic is a good idea for someone in your situation. Here is what our Stenabolic record says about it on its own.

Stenabolic: dosing

There is no established or approved dose for Stenabolic because it has never been tested in proper human studies. Doses suggested on websites and forums are not based on safety research.We cannot recommend a dose. Given the lack of safety data, the risk of contaminated products, and its banned status in sports, the safest choice is not to use it at all.

From our Stenabolic monograph — the full record covers uses, side effects and every documented interaction.

Read the full Stenabolic monograph & all interactions
Medication

About Upadacitinib

What Is Upadacitinib Used For?

Brand name: Rinvoq

Upadacitinib is approved for adults and some children with moderate-to-severe inflammatory conditions when other treatments haven't worked well enough. It targets overactive immune signaling that drives these diseases.

Conditions it treats include:

  • Rheumatoid arthritis (RA) — in adults who didn't respond to TNF blocker medications
  • Psoriatic arthritis — in adults and children 2 years and older who didn't respond to TNF blockers
  • Atopic dermatitis (eczema) — in people 12 and older whose disease isn't controlled by other systemic therapies
  • Ulcerative colitis — in adults who didn't respond to TNF blockers or other approved therapies
  • Crohn's disease — in adults who didn't respond to TNF blockers or other approved therapies

See full Upadacitinib drug information
Keep checking

Other Drugs & Stenabolic

Browse every other medication we’ve checked against Stenabolic — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Stenabolic References

The 1 references that drive our Stenabolic monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Stenabolic and Upadacitinib Hemihydrate Together: Common Questions

Is it safe to take Stenabolic with Upadacitinib Hemihydrate?
We do not list a known interaction between Stenabolic and Upadacitinib Hemihydrate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Upadacitinib Hemihydrate interact with any supplements?
Yes. Upadacitinib Hemihydrate has documented interactions with 138 supplements in our database — Stenabolic is not one of them. The Upadacitinib Hemihydrate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Upadacitinib Hemihydrate and Stenabolic?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.