Drug & supplement interaction

Thiamine + Boric Acid

Boric Acid brand names: Boric Acid, Boric acid ointment.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Thiamine and Boric Acid in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Thiamine and Boric Acid

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Boric Acid and Thiamine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Thiamine safety at a glance

Thiamine overall Generally safe Thiamine is generally very safe when taken by mouth in normal amounts.
Pregnancy Likely Safe When used orally in dietary amounts of 1.4 mg daily. A tolerable upper intake level (UL) has not been established for healthy individuals. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in dietary amounts of 1.4 mg daily. A tolerable upper intake level (UL) has not been established for healthy individuals. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Boric Acid and Thiamine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Boric Acid

Interactions in our licensed database are recorded against drug classes, not just single drug names. Boric Acid is filed under 3 classifications — antifungals, topical drugs, oral drugs. Thiamine has documented interactions with 1 drug class — the most serious being trimethoprim (proloprim) (minor) — and none of Boric Acid’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Thiamine Does Interact With Other Medications

Thiamine has 3 minor known drug interactions in our database — Boric Acid isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Thiamine

Covers the 2,830 medications we’ve checked against Thiamine. Pick one to open its full report.

What to actually watch for

What Thiamine Itself Has Been Linked To

This is not an interaction — nothing below involves Boric Acid. It is the side-effect record for Thiamine on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Thiamine, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Bleeding in the gut / Shortness of breath / A severe allergic reaction / Hives / Bleeding or bruising / An allergic reaction Worth acting on Additional detail

    “Orally, thiamine might rarely cause dermatitis and other allergic reactions. Parenterally, thiamine can cause anaphylactoid and hypersensitivity reactions, but this is also rare (”

    Thiamine · Natural Medicines adverse-effect record, reported in acute respiratory distress syndrome (ards).

    4 sources cited
    1. 15. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
    2. 35585. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
    3. 105445. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
    4. 91170. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  • Numbness or tingling / Low blood pressure / Itching / Swelling Additional detail

    Recorded for Thiamine in the same Natural Medicines adverse-effect record shown under Bleeding in the gut / Shortness of breath / A severe allergic reaction / Hives / Bleeding or bruising / An allergic reaction above.

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Thiamine — expand a row for the licensed statement it rests on. We haven’t matched Boric Acid to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Boric Acid.

Special populations

Thiamine in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in dietary amounts of 1.4 mg daily. A tolerable upper intake level (UL) has not been established for healthy individuals.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Boric Acid

This page covers Thiamine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Boric Acid page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), Dimethylsulfoxide (dmso) (moderate), European Mandrake (moderate) and Glucomannan (moderate).

By severity: 1 major · 9 moderate · 13 minor.

From our pharmacist’s overview on the Boric Acid page

“Boric acid shows up as a vaginal suppository for stubborn yeast infections or as an antiseptic ointment, and I read its interaction list with genuine caution because of one entry above all. Activated charcoal, the single major-rated interaction of the 23 on file, adsorbs many medications and can shrink how much drug the body actually t…”

Reviewed by 2 · Jul 18, 2026

Open the Boric Acid interaction page

One more smart check

Taking Thiamine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Thiamine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Thiamine. Even though Thiamine itself has no known interaction with Boric Acid, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Thiamine and Boric Acid Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Thiamine
Top 25%

#179 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Boric Acid
Steady interest

#1,741 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Thiamine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Thiamine and Boric Acid records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Thiamine

What is Thiamine?

  • Preventing or treating thiamine deficiency
  • Beriberi
  • Wernicke-Korsakoff syndrome (alcohol-related)
  • Supporting energy and nerve function
  • General B-vitamin supplementation

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clearly useful for deficiency, certain medical conditions, and people with heavy alcohol use. Talk with your pharmacist or doctor before starting it, especially if you have a chronic illness.

Tablets, capsules, oral liquids, injectable solutions (prescription), part of B-complex and multivitamins

An interaction check asks whether these two react with each other — it does not ask whether Thiamine is a good idea for someone in your situation. Here is what our Thiamine record says about it on its own.

Thiamine: dosing

The right dose of thiamine depends on your age, health, and the reason you are taking it. There is a recommended daily intake for general nutrition, and higher amounts are sometimes used by doctors to treat a deficiency.For supplements, the best approach is to follow the directions on the product label and not exceed them without guidance.

From our Thiamine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Thiamine monograph & all interactions
Medication

About Boric Acid

Most-Reported Side Effects for Boric Acid

From FAERS, the FDA’s public side-effect reporting system (345 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Arthralgia 114 reports
Pain in extremity 113 reports
Joint swelling 112 reports
Infection 110 reports
Musculoskeletal stiffness 110 reports
Keep checking

Other Drugs & Thiamine

Browse every other medication we’ve checked against Thiamine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
3Minor
2,826No known interaction
Minor

3 interactions

No interaction 2,826 drugs checked — show the list
Evidence & sources

Thiamine References

The 7 references that drive our Thiamine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Thiamine and Boric Acid Together: Common Questions

Is it safe to take Thiamine with Boric Acid?
We do not list a known interaction between Thiamine and Boric Acid. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Thiamine and Boric Acid combination checked?
Interactions in our licensed database are recorded against drug classes. Boric Acid is filed under 3 classifications, and Thiamine has documented interactions with 1 drug class — none of Boric Acid's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Thiamine interact with any other medications?
Yes. Thiamine has 3 documented drug interactions in our database — Boric Acid is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Boric Acid interact with any supplements?
Yes. Boric Acid has documented interactions with 23 supplements in our database — Thiamine is not one of them. The Boric Acid interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Boric Acid and Thiamine?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.