Tin + Levothyroxine
Levothyroxine brand names: Euthyrox, Levothroid, Unithroid, Synthroid, Levoxyl, and others.
We found no known interaction between Tin and Levothyroxine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Levothyroxine states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Tin and Levothyroxine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Levothyroxine and Tin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Tin at all — not against Levothyroxine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Tin safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Levothyroxine Products Have a Food Rule — Tin Should Not Break It
At least one FDA label for a product containing Levothyroxine says to take it on an empty stomach. Most supplements — Tin included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Levothyroxine on its own and move Tin to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Levothyroxine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
Questions About Tin or Levothyroxine
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tin or Levothyroxine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Levothyroxine 88 mcg Tablets Changed From Green to Lavender ›
- Black Currant Oil With Levothyroxine, Methotrexate, and a Statin ›
- Provitalize With Levothyroxine, Valacyclovir, and Citalopram ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Levothyroxine
This page covers Tin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Levothyroxine page lists 50 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Tiratricol (major), Acetyl-l-carnitine (moderate), Alpha-lipoic Acid (moderate) and Ascophyllum Nodosum (moderate).
By severity: 2 major · 39 moderate · 9 minor.
From our pharmacist’s overview on the Levothyroxine page
“Levothyroxine replaces a hormone your body measures in tiny amounts, so small shifts in its blood level show up in how you feel, and I treat this list with genuine care. Nearly everything on it does one of two things: blocks the pill from being absorbed in the gut, the way everyday minerals like calcium do by binding it into complexes,…”
Reviewed by 2 · Jul 18, 2026
Taking Tin as Part of a Dietary Supplement Product? Check It for Interactions
We hold 384 real supplement products containing Tin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tin. Even though Tin itself has no known interaction with Levothyroxine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Tin and Levothyroxine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#399 of 1,452 supplements looked up here in the last 7 days
#2 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tin reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Tin and Levothyroxine records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Tin
What is Tin?
- Marketed as a trace mineral supplement
- Claimed support for general 'mineral balance'
- Sometimes promoted for skin or hair (unproven)
Tin is a metallic element found in tiny amounts in the diet, but it is not considered an essential nutrient for humans and there is no proven health benefit to taking it as a supplement. Because some tin compounds can be toxic, there is little reason to take tin on purpose, and you should talk to a pharmacist or doctor before using any product that contains it.
Tin is a chemical element (Sn); the form used in supplements is the trace mineral, not a plant part · Trace amounts in some multivitamin/mineral products; stannous salts are used in some toothpastes (not as a supplement)
An interaction check asks whether these two react with each other — it does not ask whether Tin is a good idea for someone in your situation. Here is what our Tin record says about it on its own.
Tin: dosing
There is no established or recommended dose of tin as a supplement, because it is not known to be an essential nutrient. No official daily requirement has been set for humans.If a product you are considering lists tin, follow the label and keep the amount low, but understand there is no proven reason to take it.
From our Tin monograph — the full record covers uses, side effects and every documented interaction.
About Levothyroxine
What Is Levothyroxine Used For?
Brand names: Euthyrox, Levothroid, Unithroid, Synthroid, Levoxyl, Levo-T, Eltroxin, Estre, Levothyroxine, Novothyrox, Levolet
Levothyroxine replaces thyroid hormone when your body does not make enough. The oral products (tablets, capsules and oral solution) treat hypothyroidism, which can be present from birth or develop later. They are also used alongside surgery and radioiodine therapy for thyrotropin-dependent well-differentiated thyroid cancer.
Levothyroxine Sodium injection (given intravenously) is used only for myxedema coma, a life-threatening emergency from severe hypothyroidism. Age ranges differ by product. For example, Tirosint capsules are labeled for adults and children 6 years and older.
Most-Reported Side Effects for Levothyroxine
From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Tin
Browse every other medication we’ve checked against Tin — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Tin against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Escitalopram ›
- Metoprolol ›
- Clopidogrel ›
- Atorvastatin ›
- Rivaroxaban ›
- Isotretinoin ›
- Warfarin Sodium ›
- Tirzepatide ›
- Amlodipine Besylate ›
- Ibuprofen ›
- Methamphetamine ›
- Docusate ›
- Tadalafil ›
- Hydroxyurea ›
- Valacyclovir ›
- Metformin ›
- Sumatriptan ›
- Prednisone ›
- Semaglutide ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Amphetamine ›
- Levothyroxine, Liothyronine ›
- Propranolol ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Bendamustine ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Dextroamphetamine ›
- Lamotrigine ›
- Acyclovir ›
- Acetaminophen, Aspirin, Caffeine ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
- Acetaminophen, Codeine ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tin list.
Tin References
The 8 references that drive our Tin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- US Department of Health and Human Services. Toxicological profile for tin and tin compounds. Available at: http://www.atsdr.cdc.gov/toxprofiles/tp55.pdf
- Paraskevas, S. and van der Weijden, G. A. A review of the effects of stannous fluoride on gingivitis. J Clin Periodontol 2006;33(1):1-13. PubMed
- Blunden, S. and Wallace, T. Tin in canned food: a review and understanding of occurrence and effect. Food Chem Toxicol 2003;41(12):1651-1662. PubMed
- Sälzer S, Slot DE, Dörfer CE, Van der Weijden GA. Comparison of triclosan and stannous fluoride dentifrices on parameters of gingival inflammation and plaque scores: a systematic review and meta-analysis. Int J Dent Hyg. 2015 Feb;13(1):1-17.
- Feng X, Chen X, Cheng R, Sun L, Zhang Y, He T. Breath malodor reduction with use of a stannous-containing sodium fluoride dentifrice: a meta-analysis of four randomized and controlled clinical trials. Am J Dent. 2010;23 Spec No B:27B-31B.
- Milleman JL, Milleman KR, Santos SL, Proskin HM, Battershell KK, DiMarino JC. Subjective assessment of Enamelon® preventive treatment gel in a self-reported dry-mouth population. Compend Contin Educ Dent. 2016;37(8):e5-8.
- Lorenz K, Hoffmann T, Heumann C, Noack B. Effect of toothpaste containing amine fluoride and stannous chloride on the reduction of dental plaque and gingival inflammation. A randomized controlled 12-week home-use study. Int J Dent Hyg. 2019;17(3):237-243. PubMed
- Frese C, Wohlrab T, Sheng L, Kieser M, Krisam J, Wolff D. Clinical effect of stannous fluoride and amine fluoride containing oral hygiene products: A 4-year randomized controlled pilot study. Sci Rep 2019;9(1):7681. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Tin and Levothyroxine Together: Common Questions
Is it safe to take Tin with Levothyroxine?
Do Tin and Levothyroxine have any of the same side effects?
Should I take Tin and Levothyroxine at the same time of day?
Does Levothyroxine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.