Tolu Balsam + Bosutinib
Bosutinib brand name: Bosulif.
We found no known interaction between Tolu Balsam and Bosutinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Bosutinib states a food rule worth keeping to.
Tolu Balsam and Bosutinib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Bosutinib and Tolu Balsam in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Tolu Balsam at all — not against Bosutinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Tolu Balsam safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Bosutinib Products Have a Food Rule — Tolu Balsam Should Not Break It
At least one FDA label for a product containing Bosutinib says to take it with food. If you take Tolu Balsam on an empty stomach out of habit, keep them separate — and take Bosutinib with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Bosutinib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Adult patients with newly-diagnosed chronic phase Ph+ CML: 400 mg orally once daily with food.
From the Dosage and Administration section of the FDA label we read for Bosutinib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Bosutinib
This page covers Tolu Balsam only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bosutinib page lists 172 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Grapefruit (major) and Siberian Cocklebur (major).
By severity: 7 major · 126 moderate · 39 minor.
From our pharmacist’s overview on the Bosutinib page
“Grapefruit is the first thing to know about if you take bosutinib (Bosulif) for chronic myeloid leukemia. Bosutinib is cleared by the enzyme CYP3A4, and grapefruit blocks that pathway, so drug levels climb and side effects with them.”
Reviewed by 2 · Jul 18, 2026
Taking Tolu Balsam as Part of a Dietary Supplement Product? Check It for Interactions
We hold 3 real supplement products containing Tolu Balsam, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tolu Balsam. Even though Tolu Balsam itself has no known interaction with Bosutinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Tolu Balsam and Bosutinib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,117 of 1,452 supplements looked up here in the last 7 days
#1,431 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Tolu Balsam and Bosutinib records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Tolu Balsam
What is Tolu Balsam?
- Cough and sore throat
- Chest congestion
- Wound and skin care (topical)
- Flavoring and fragrance
- Mild expectorant
Tolu balsam is a fragrant resin from a South American tree that has long been used as a flavoring and as an ingredient in cough syrups and throat lozenges. Good-quality human studies are lacking, so its real effectiveness is uncertain, and it can cause allergic skin reactions in some people. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have allergies.
Myroxylon balsamum · Fabaceae · Resinous balsam (oleoresin) collected from the tree trunk · Syrups, cough lozenges, throat preparations, tinctures, and as a flavoring or fragrance ingredient
An interaction check asks whether these two react with each other — it does not ask whether Tolu Balsam is a good idea for someone in your situation. Here is what our Tolu Balsam record says about it on its own.
Tolu Balsam: dosing
There is no well-established standardized dose for tolu balsam. It is most often found as a minor ingredient in cough syrups, lozenges, and tinctures rather than taken on its own.If you use a product that contains tolu balsam, follow the directions on the label and do not exceed the recommended amount.
From our Tolu Balsam monograph — the full record covers uses, side effects and every documented interaction.
About Bosutinib
What Is Bosutinib Used For?
Brand name: Bosulif
Bosutinib is used to treat Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) — a type of blood cancer. It can be used for newly diagnosed patients or for those whose cancer has stopped responding to, or who cannot tolerate, a prior treatment.
Bosulif (the brand-name product) is approved for adults and children 1 year and older with chronic phase Ph+ CML, and for adults with accelerated phase or blast phase Ph+ CML that is resistant or intolerant to prior therapy. Generic bosutinib tablets are approved for adults only with the same range of disease phases.
Most-Reported Side Effects for Bosutinib
From FAERS, the FDA’s public side-effect reporting system (8,931 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Tolu Balsam
Browse every other medication we’ve checked against Tolu Balsam — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Tolu Balsam against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Aspirin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Acetaminophen ›
- Escitalopram ›
- Tadalafil ›
- Abemaciclib ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Ibuprofen ›
- Tirzepatide ›
- Methamphetamine ›
- Semaglutide ›
- Warfarin Sodium ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Amitriptyline ›
- Bendamustine ›
- Acyclovir ›
- Methotrexate ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Pregabalin ›
- Lamotrigine ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Gabapentin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Omeprazole ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Naproxen ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tolu Balsam list.
Sources & How We Checked
We checked Tolu Balsam against Bosutinib in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Tolu Balsam and Bosutinib Together: Common Questions
Is it safe to take Tolu Balsam with Bosutinib?
Should I take Tolu Balsam and Bosutinib at the same time of day?
Does Bosutinib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Still Have a Question About Bosutinib and Tolu Balsam?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.