Drug & supplement interaction

Vietnamese Coriander + Donepezil

Donepezil brand name: Aricept.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Vietnamese Coriander and Donepezil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Vietnamese Coriander and Donepezil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Donepezil and Vietnamese Coriander in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Vietnamese Coriander at all — not against Donepezil, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Vietnamese Coriander safety at a glance

Vietnamese Coriand... overall Use caution Likely safe as a food flavoring, but medicinal amounts are not well studied in humans.
Pregnancy Avoid Traditionally avoided in pregnancy and not proven safe in medicinal amounts.
Breastfeeding Avoid Not enough safety information, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Donepezil and Vietnamese Coriander? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Donepezil’s Own FDA Label Lists

This is not an interaction — none of it involves Vietnamese Coriander. These are the most notable effects listed in the ADVERSE REACTIONS section of Donepezil’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • Bleeding in the gut Worth acting on
  • Seizures Worth acting on
  • Bleeding or bruising Worth acting on
  • Weight loss
  • Reduced appetite
  • Muscle pain
  • Trouble sleeping
  • Tiredness mentioned in 4.8% of FDA reports for Donepezil
  • Diarrhea mentioned in 5.0% of FDA reports for Donepezil
  • Nausea mentioned in 4.6% of FDA reports for Donepezil

Showing the 10 most notable of 11 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Donepezil. Read the label on DailyMed › Where a percentage is shown, it is the share of 37,026 voluntary FDA FAERS reports for Donepezil that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Vietnamese Coriander’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Vietnamese Coriander side to compare — that is a limit of the record, not a statement that Vietnamese Coriander has no side effects.

From our Q&A

Questions About Vietnamese Coriander or Donepezil

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Vietnamese Coriander or Donepezil, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Donepezil

This page covers Vietnamese Coriander only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Donepezil page lists 173 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 127 moderate · 43 minor.

From our pharmacist’s overview on the Donepezil page

“If you or a loved one takes donepezil (Aricept) for Alzheimer's disease, this is a list worth reading with real care, starting with the three major-rated entries: grapefruit, St. John's wort, and activated charcoal.”

Reviewed by 2 · Jul 18, 2026

Open the Donepezil interaction page

How much people look this up

Where Vietnamese Coriander and Donepezil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Vietnamese Coriander
Steady interest

#1,348 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Donepezil
Steady interest

#1,793 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Vietnamese Coriander is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Vietnamese Coriander reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Vietnamese Coriander and Donepezil records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Vietnamese Coriander

What is Vietnamese Coriander?

  • Flavoring food
  • Digestive upset
  • Antimicrobial uses
  • Reducing sexual desire (traditional)
  • Skin and wound care (traditional)

Vietnamese coriander (rau ram) is a fragrant Southeast Asian culinary herb traditionally used for digestion and as an antimicrobial. There is very little human research to support its medicinal uses, so it is best thought of as a flavorful food rather than a proven remedy. Pregnant and breastfeeding people should avoid medicinal amounts, and anyone considering it as a supplement should check with a pharmacist or doctor.

Persicaria odorata · Polygonaceae · Leaves and stems · Fresh leaves (culinary herb), dried leaves, tea, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Vietnamese Coriander is a good idea for someone in your situation. Here is what our Vietnamese Coriander record says about it on its own.

Vietnamese Coriander: dosing

There is no established or standardized medicinal dose for Vietnamese coriander. It is most often used simply as a fresh culinary herb, added to dishes to taste.If you choose to use a tea or supplement product, follow the directions on the label and do not exceed the recommended amount.

From our Vietnamese Coriander monograph — the full record covers uses, side effects and every documented interaction.

Read the full Vietnamese Coriander monograph & all interactions
Medication

About Donepezil

What Is Donepezil Used For?

Brand name: Aricept

Donepezil is used to treat dementia of the Alzheimer's type. It has been shown to be effective across all stages — mild, moderate, and severe Alzheimer's disease.

It can help with memory, thinking, and daily functioning, though it works differently for each person. Donepezil does not cure Alzheimer's disease or stop the disease from progressing.

Most-Reported Side Effects for Donepezil

From FAERS, the FDA’s public side-effect reporting system (37,026 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fall 3,130 reports
Confusional state 2,010 reports
Dizziness 1,857 reports
Diarrhea 1,840 reports
Fatigue 1,794 reports
See full Donepezil drug information
Keep checking

Other Drugs & Vietnamese Coriander

Browse every other medication we’ve checked against Vietnamese Coriander — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Vietnamese Coriander against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Vietnamese Coriander list.

See the full Vietnamese Coriander interactions page
See every supplement checked against Donepezil, ranked by severity
Evidence & sources

Vietnamese Coriander References

The 2 sources that drive our Vietnamese Coriander monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Vietnamese Coriander is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
  2. Herbal Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Vietnamese Coriander and Donepezil Together: Common Questions

Is it safe to take Vietnamese Coriander with Donepezil?
We do not list a known interaction between Vietnamese Coriander and Donepezil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Donepezil interact with any supplements?
Yes. Donepezil has documented interactions with 173 supplements in our database — Vietnamese Coriander is not one of them. The Donepezil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Vietnamese Coriander monograph Uses, safety profile, and every drug interaction in one place Donepezil drug information The full plain-English guide to this medication Donepezil supplement interactions Every supplement checked against Donepezil, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Donepezil and Vietnamese Coriander?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.