White Sandalwood + Hydroxyzine
Hydroxyzine brand names: Atarax, Vistaril, Ucerax.
We found no known interaction between White Sandalwood and Hydroxyzine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
White Sandalwood and Hydroxyzine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Hydroxyzine and White Sandalwood in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
White Sandalwood safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Hydroxyzine
Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydroxyzine is filed under 5 classifications — including anticholinergic drugs, photosensitizing drugs, seizure threshold lowering drugs. White Sandalwood has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Hydroxyzine’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
White Sandalwood Does Interact With Other Medications
White Sandalwood has 1 moderate known drug interaction in our database — Hydroxyzine isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against White Sandalwood
We haven’t checked that one against White Sandalwood yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against White Sandalwood. Pick one to open its full report.
White Sandalwood in Pregnancy & Breastfeeding
When used orally in medicinal amounts; sandalwood is reported to have abortifacient effects; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Hydroxyzine Is Prescribed For, and What White Sandalwood Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Hydroxyzine is a prescription medicine with approved uses on its FDA label. White Sandalwood is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Hydroxyzine is prescribed for: Hydroxyzine is used to relieve anxiety and tension related to psychoneurosis (anxiety-based mental health conditions) and as a supportive treatment when anxiety is part of another medical condition. Oral forms — including tablets, capsules, and oral solution — are used for anxiety relief and to manage itching (pruritus) caused by allergic conditions such as chronic urticaria (hives), atopic dermatitis, contact dermatitis, and histamine-driven itch. Oral forms are also used as a sedative before and after surgery or general anesthesia. Hydroxyzine Hydrochloride intramuscular injection is used specifically when a shot is needed — for example, in acute psychiatric or emotional emergencies, acute alcohol withdrawal with anxiety symptoms or delirium tremens, control of nausea and vomiting (except during pregnancy), and as pre- and post-operative or pre- and post-partum supportive medication to reduce narcotic requirements and control nausea.
White Sandalwood has been studied for:
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Anxiety studied, not established White Sandalwood has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
White Sandalwood for anxiety
Although there has been interest in using inhaled white sandalwood for anxiety, there is insufficient reliable information about the clinical effects of white sandalwood for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Hydroxyzine on your own; if you are taking White Sandalwood for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About White Sandalwood or Hydroxyzine
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers White Sandalwood or Hydroxyzine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Questions About Combining Hydroxyzine And Buspirone ›
- Can You Take Turmeric With Hydroxyzine? ›
- Can You Take Prozac And Ibuprofen Together? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Hydroxyzine
This page covers White Sandalwood only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydroxyzine page lists 183 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), Henbane (major), Scopolia (major) and St. John's Wort (major).
By severity: 5 major · 135 moderate · 43 minor.
From our pharmacist’s overview on the Hydroxyzine page
“Hydroxyzine (Atarax, Vistaril) is a sedating antihistamine for itching and anxiety, so read this list closely before pairing it with any supplement. Five of the 183 ingredients on file rate major, and those come first: grapefruit and St.”
Reviewed by 2 · Jul 18, 2026
Taking White Sandalwood as Part of a Dietary Supplement Product? Check It for Interactions
We hold 22 real supplement products containing White Sandalwood, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Sandalwood. Even though White Sandalwood itself has no known interaction with Hydroxyzine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where White Sandalwood and Hydroxyzine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#996 of 1,452 supplements looked up here in the last 7 days
#467 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Sandalwood reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The White Sandalwood and Hydroxyzine records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About White Sandalwood
What is White Sandalwood?
- Relaxation and stress relief
- Skin soothing and cosmetics
- Aromatherapy and meditation
- Traditional remedy for urinary discomfort
- Fragrance and perfumes
White sandalwood is a fragrant wood from the Santalum album tree, used for centuries in perfumes, incense, skincare, and traditional medicine. Most of its popular uses—like relaxation and skin care—are based on tradition and lab studies rather than strong human research. Use it cautiously, especially on the skin or by mouth, and talk to your pharmacist or doctor before using it as a remedy.
Santalum album · Santalaceae · Heartwood and essential oil · Essential oil, powder, paste, incense, skincare products, and occasionally capsules or tablets
An interaction check asks whether these two react with each other — it does not ask whether White Sandalwood is a good idea for someone in your situation. Here is what our White Sandalwood record says about it on its own.
White Sandalwood: dosing
There is no established standardized dose for white sandalwood, and reliable human dosing information for oral use is lacking. Never swallow undiluted essential oil, and dilute oils properly before applying them to your skin. When in doubt, choose products from reputable manufacturers and use the smallest amount needed.
From our White Sandalwood monograph — the full record covers uses, side effects and every documented interaction.
About Hydroxyzine
What Is Hydroxyzine Used For?
Brand names: Atarax, Vistaril, Ucerax
Hydroxyzine is used to relieve anxiety and tension related to psychoneurosis (anxiety-based mental health conditions) and as a supportive treatment when anxiety is part of another medical condition. Oral forms — including tablets, capsules, and oral solution — are used for anxiety relief and to manage itching (pruritus) caused by allergic conditions such as chronic urticaria (hives), atopic dermatitis, contact dermatitis, and histamine-driven itch. Oral forms are also used as a sedative before and after surgery or general anesthesia.
Hydroxyzine Hydrochloride intramuscular injection is used specifically when a shot is needed — for example, in acute psychiatric or emotional emergencies, acute alcohol withdrawal with anxiety symptoms or delirium tremens, control of nausea and vomiting (except during pregnancy), and as pre- and post-operative or pre- and post-partum supportive medication to reduce narcotic requirements and control nausea.
Most-Reported Side Effects for Hydroxyzine
From FAERS, the FDA’s public side-effect reporting system (50,845 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & White Sandalwood
Browse every other medication we’ve checked against White Sandalwood — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked White Sandalwood against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Warfarin Sodium ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Acyclovir ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Fluoxetine ›
- Lamotrigine ›
- Acetaminophen, Codeine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Dextroamphetamine ›
- Azithromycin ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Methylene Blue ›
- Quetiapine ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full White Sandalwood list.
White Sandalwood References
The 5 references that drive our White Sandalwood monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Sharma, R., Bajaj, A. K., and Singh, K. G. Sandalwood dermatitis. Int J Dermatol 1987;26(9):597. PubMed
- Hayakawa, R., Matsunaga, K., and Arima, Y. Depigmented contact dermatitis due to incense. Contact Dermatitis 1987;16(5):272-274. PubMed
- Warshaw EM, Zug KA, Belsito DV, et al. Positive patch-test reactions to essential oils in consecutive patients from North America and Central Europe. Dermatitis. 2017;28(4):246-252. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking White Sandalwood and Hydroxyzine Together: Common Questions
Is it safe to take White Sandalwood with Hydroxyzine?
Do White Sandalwood and Hydroxyzine have any of the same side effects?
Are White Sandalwood and Hydroxyzine used for the same thing?
How was the White Sandalwood and Hydroxyzine combination checked?
Does White Sandalwood interact with any other medications?
Does Hydroxyzine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.