Smooth Alder Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Smooth Alder interacts with medications. The heart of this page is the interaction list — every drug Smooth Alder is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Smooth Alder is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Smooth Alder against your medication
Add one medicationDrugs that interact with Smooth Alder
0 medications have a known interaction with Smooth Alder, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Smooth Alder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Smooth Alder combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Smooth Alder: Uses, Safety & Side Effects
Smooth Alder is a North American shrub used in traditional and folk medicine, mainly as an astringent for skin and mouth complaints. Modern scientific evidence supporting any health benefit is very limited, so it should be used cautiously and never as a substitute for proven treatments.
- Scientific name
- Alnus serrulata
- Family
- Betulaceae
- Part used
- Bark, leaves, and sometimes cones
- Common forms
- Tea, decoction, tincture, topical wash
- Skin irritation and wounds
- Sore throat and mouth rinse
- Digestive complaints
- Astringent for inflammation
- Traditional fever remedy
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
There is very little research on its safety in humans, so caution is warranted.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Smooth Alder (often identified as Alnus serrulata) is a shrub or small tree in the birch family that grows in wet areas, along streams, and in swampy ground across eastern North America. It is sometimes called tag alder or hazel alder.
Traditionally, Native American and folk healers used the bark, leaves, and cones to make teas, washes, and tinctures. Because the bark is rich in tannins, it has an astringent (tightening) quality that led to its use for skin problems, mouth and throat irritation, and minor digestive complaints.
Today Smooth Alder is uncommon as a commercial supplement and is mostly of interest for its traditional and historical uses.
Uses & effectiveness
People have traditionally used Smooth Alder as an astringent applied to the skin for cuts, rashes, and inflammation, and as a gargle or mouth rinse for sore throats and irritated gums. It has also been taken as a tea for diarrhea, indigestion, and fevers.
The scientific evidence for these uses is very limited. Most of what is known comes from traditional practice and a small amount of laboratory research on alder species. There are no high-quality human clinical trials proving that Smooth Alder treats any condition.
Because the evidence is weak, you should not rely on Smooth Alder in place of proven medical care. Talk with a pharmacist or doctor before trying it.
How it works
The bark and leaves of alder plants contain tannins, which are plant compounds that bind to proteins. This is thought to give the plant its astringent effect, helping tissues feel tighter and possibly reducing minor oozing or irritation.
Alder species also contain other compounds such as flavonoids and related plant chemicals that have shown antioxidant or antimicrobial activity in some laboratory studies. However, these findings come mostly from test-tube or animal research and do not prove that Smooth Alder works the same way in the human body.
Safety & precautions
There is very little formal safety research on Smooth Alder, so its overall safety is best considered unknown. Tannin-rich plant products may upset the stomach, especially in larger amounts or with long-term use.
People with known allergies to birch-family plants or related pollens may be more likely to react to alder. If you have a chronic medical condition, are taking medications, or are scheduled for surgery, check with your pharmacist or doctor first.
Pregnancy and breastfeeding: Because there is no reliable safety information, Smooth Alder should be avoided during pregnancy and while breastfeeding. Do not give it to infants or young children.
Side effects
Reported side effects are not well documented because the plant has not been carefully studied. Based on its high tannin content, possible effects include stomach upset, nausea, or constipation, particularly with strong or frequent doses.
Allergic reactions are possible in sensitive people. Stop using it and seek medical care if you notice rash, swelling, trouble breathing, or other signs of an allergic reaction.
Dosing
There is no established standardized dose for Smooth Alder. It has been used traditionally as a tea or topical wash made from the bark or leaves, but reliable, tested dosing guidelines do not exist.
If you choose to use a product, follow the directions on the label and do not exceed them. Because quality and strength can vary between products, talk with a pharmacist before starting, and stop if you notice any unwanted effects.
Smooth Alder & Pregnancy
Smooth Alder & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 2 sources that drive our Smooth Alder monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.
Keep readingThis information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Brands that make products with Smooth Alder
2 brands in our database make a supplement containing Smooth Alder.
Supplement products with Smooth Alder
2 products in our database contain Smooth Alder. Open any to see its full ingredient list and every drug interaction we check.
Smooth Alder: Common Questions
Does Smooth Alder interact with prescription medications?
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How is Smooth Alder usually taken?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Smooth Alder
A rotating sample of real supplements in our database that list Smooth Alder — open any to see its full ingredients and every drug interaction we check.
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