Bogbean Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Bogbean interacts with medications. The heart of this page is the interaction list — every drug Bogbean is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Bogbean is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Bogbean against your medication
Add one medicationDrugs that interact with Bogbean
0 medications have a known interaction with Bogbean, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Bogbean. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Bogbean combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Bogbean: Uses, Safety & Side Effects
Bogbean is a wetland plant whose bitter leaves have long been used in folk medicine for joint pain, poor appetite, and digestion. Good-quality human studies are lacking, so its benefits are unproven, and large amounts can upset the stomach. Talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.
- Scientific name
- Menyanthes trifoliata
- Family
- Menyanthaceae
- Part used
- Leaves (and sometimes the roots/rhizome)
- Common forms
- Tea, tincture, liquid extract, capsules, dried herb
- Rheumatoid arthritis and joint pain
- Poor appetite and digestive upset
- Bitter tonic
- Scurvy (traditional)
- Fever (traditional)
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Limited safety data; large doses may cause stomach upset, nausea, vomiting, or diarrhea.
When used orally due to the lack of toxicity information and its possible purgative action; avoid using.
Read the full pregnancy detailWhen used orally due to the lack of toxicity information and its possible purgative action; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Bogbean (Menyanthes trifoliata) is a flowering water plant that grows in bogs, marshes, ponds, and other wet areas across Europe, Asia, and North America. It has three-part leaves and pretty pink-white fringed flowers.
The leaves are very bitter, and traditional herbalists have used them as a "bitter tonic" to stimulate appetite and digestion. In folk medicine it has also been used for joint problems like rheumatism and arthritis, and historically for scurvy because the plant contains vitamin C. Today it is sold as a tea, tincture, liquid extract, or capsule.
Uses & effectiveness
People most often use bogbean for joint and muscle pain (such as rheumatoid arthritis), poor appetite, and digestive complaints. It has also been used traditionally for fever and, long ago, for scurvy.
It is important to be honest here: there is very little high-quality human research on bogbean. Most of what we know comes from traditional use and a small amount of laboratory or test-tube research suggesting possible antioxidant or antibacterial activity. These early findings do not prove that bogbean treats any disease in people.
Because the evidence is weak, bogbean should not replace proven treatments for arthritis or any other medical condition. If you are considering it, talk with your pharmacist or doctor first.
How it works
Bogbean leaves contain bitter compounds (such as secoiridoid glycosides), flavonoids, tannins, and some vitamin C. The intense bitterness is thought to stimulate saliva and digestive juices, which may be why it was used to boost appetite and ease digestion.
Laboratory studies suggest the plant's flavonoids and other plant chemicals may have antioxidant and possibly antibacterial effects. However, these effects have mostly been seen in test tubes or animals, not in well-designed human studies, so we cannot say how meaningful they are for real-world health.
Safety & precautions
There is not much reliable safety information about bogbean. When used in small, traditional amounts it has generally been tolerated, but larger doses can irritate the stomach and gut.
People who should be especially careful or avoid it include those with stomach ulcers, acid reflux, inflammatory bowel disease, or ongoing diarrhea, since the bitter and tannin compounds may make these worse.
Pregnancy and breastfeeding: Because there is not enough information to confirm it is safe, bogbean should be avoided if you are pregnant, trying to become pregnant, or breastfeeding.
Always choose products from reputable manufacturers, since herbal supplements are not tightly regulated and quality can vary. Check with a pharmacist or doctor before starting bogbean, especially if you take prescription medicines or have a health condition.
Side effects
The most commonly reported side effects involve the digestive system, especially with larger amounts. These can include:
- Nausea and vomiting
- Stomach upset or cramping
- Diarrhea
Allergic reactions are possible with any plant product. Stop using bogbean and seek medical help if you develop a rash, swelling, trouble breathing, or other signs of a serious reaction.
Bogbean: Reported Adverse Effects
Documented safety reports on Bogbean from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, bogbean seems to be generally well tolerated. Excessive doses of bogbean can irritate the GI tract, and cause diarrhea, pain, nausea, and vomiting.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Diarrhea Gastrointestinal
Orally, excessive doses of bogbean can irritate the GI tract and cause diarrhea, pain, nausea, and vomiting.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established, standardized dose for bogbean. Traditional use typically involves small amounts of the dried leaf as a tea or a measured dose of tincture or extract.
Because strengths vary widely between products, the safest approach is to follow the directions on the product label and not exceed the recommended amount. More is not better with this bitter herb, since larger doses are more likely to cause stomach upset. Check with your pharmacist or doctor before using it, especially for children, older adults, or anyone with a health condition.
Bogbean & Pregnancy
Bogbean & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Bogbean monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Bogbean
4 brands in our database make a supplement containing Bogbean.
Supplement products with Bogbean
11 products in our database contain Bogbean. Open any to see its full ingredient list and every drug interaction we check.
Bogbean: Common Questions
Does Bogbean interact with prescription medications?
How are Bogbean interactions rated?
Is it safe to take Bogbean with my medications?
Where does this Bogbean interaction information come from?
What is Bogbean used for?
Is Bogbean safe to take?
Can I use Bogbean while pregnant or breastfeeding?
Does Bogbean actually help arthritis?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Bogbean
A rotating sample of real supplements in our database that list Bogbean — open any to see its full ingredients and every drug interaction we check.
- Gallexier Herbal Bitters by Floradix
- Buckbean (Bogbean) Leaf Strawberry Flavor by TerraVita
- Buckbean (Bogbean) Leaf by TerraVita
- Buckbean (Bogbean) Leaf 450 mg by TerraVita Premium Collection
- Buckbean (Bogbean) Leaf Chocolate Flavor by TerraVita
- Buckbean (Bogbean) Leaf Vanilla Flavor by TerraVita
- Buckbean (Bogbean) Leaf Powder by TerraVita Premium Collection
- Buckbean (Bogbean) Leaf Powder by TerraVita Premium Collection
- Buckbean (Bogbean) Leaf Mint Flavor by TerraVita
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