Herb & supplement monograph

Bogbean Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Bogbean

0 medications have a known interaction with Bogbean, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Bogbean. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Bogbean combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Bogbean: Uses, Safety & Side Effects

The bottom line

Bogbean is a wetland plant whose bitter leaves have long been used in folk medicine for joint pain, poor appetite, and digestion. Good-quality human studies are lacking, so its benefits are unproven, and large amounts can upset the stomach. Talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Scientific name
Menyanthes trifoliata
Family
Menyanthaceae
Part used
Leaves (and sometimes the roots/rhizome)
Common forms
Tea, tincture, liquid extract, capsules, dried herb
People commonly use it for
  • Rheumatoid arthritis and joint pain
  • Poor appetite and digestive upset
  • Bitter tonic
  • Scurvy (traditional)
  • Fever (traditional)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Limited safety data; large doses may cause stomach upset, nausea, vomiting, or diarrhea.

PregnancyPossibly Unsafe

When used orally due to the lack of toxicity information and its possible purgative action; avoid using.

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally due to the lack of toxicity information and its possible purgative action; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Bogbean (Menyanthes trifoliata) is a flowering water plant that grows in bogs, marshes, ponds, and other wet areas across Europe, Asia, and North America. It has three-part leaves and pretty pink-white fringed flowers.

The leaves are very bitter, and traditional herbalists have used them as a "bitter tonic" to stimulate appetite and digestion. In folk medicine it has also been used for joint problems like rheumatism and arthritis, and historically for scurvy because the plant contains vitamin C. Today it is sold as a tea, tincture, liquid extract, or capsule.

Uses & effectiveness

People most often use bogbean for joint and muscle pain (such as rheumatoid arthritis), poor appetite, and digestive complaints. It has also been used traditionally for fever and, long ago, for scurvy.

It is important to be honest here: there is very little high-quality human research on bogbean. Most of what we know comes from traditional use and a small amount of laboratory or test-tube research suggesting possible antioxidant or antibacterial activity. These early findings do not prove that bogbean treats any disease in people.

Because the evidence is weak, bogbean should not replace proven treatments for arthritis or any other medical condition. If you are considering it, talk with your pharmacist or doctor first.

How it works

Bogbean leaves contain bitter compounds (such as secoiridoid glycosides), flavonoids, tannins, and some vitamin C. The intense bitterness is thought to stimulate saliva and digestive juices, which may be why it was used to boost appetite and ease digestion.

Laboratory studies suggest the plant's flavonoids and other plant chemicals may have antioxidant and possibly antibacterial effects. However, these effects have mostly been seen in test tubes or animals, not in well-designed human studies, so we cannot say how meaningful they are for real-world health.

Safety & precautions

There is not much reliable safety information about bogbean. When used in small, traditional amounts it has generally been tolerated, but larger doses can irritate the stomach and gut.

People who should be especially careful or avoid it include those with stomach ulcers, acid reflux, inflammatory bowel disease, or ongoing diarrhea, since the bitter and tannin compounds may make these worse.

Pregnancy and breastfeeding: Because there is not enough information to confirm it is safe, bogbean should be avoided if you are pregnant, trying to become pregnant, or breastfeeding.

Always choose products from reputable manufacturers, since herbal supplements are not tightly regulated and quality can vary. Check with a pharmacist or doctor before starting bogbean, especially if you take prescription medicines or have a health condition.

Side effects

The most commonly reported side effects involve the digestive system, especially with larger amounts. These can include:

  • Nausea and vomiting
  • Stomach upset or cramping
  • Diarrhea

Allergic reactions are possible with any plant product. Stop using bogbean and seek medical help if you develop a rash, swelling, trouble breathing, or other signs of a serious reaction.

Bogbean: Reported Adverse Effects

Documented safety reports on Bogbean from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, bogbean seems to be generally well tolerated. Excessive doses of bogbean can irritate the GI tract, and cause diarrhea, pain, nausea, and vomiting.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Reports by condition
Diarrhea Gastrointestinal

Orally, excessive doses of bogbean can irritate the GI tract and cause diarrhea, pain, nausea, and vomiting.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no well-established, standardized dose for bogbean. Traditional use typically involves small amounts of the dried leaf as a tea or a measured dose of tincture or extract.

Because strengths vary widely between products, the safest approach is to follow the directions on the product label and not exceed the recommended amount. More is not better with this bitter herb, since larger doses are more likely to cause stomach upset. Check with your pharmacist or doctor before using it, especially for children, older adults, or anyone with a health condition.

Pregnancy & Breastfeeding

Bogbean & Pregnancy

Possibly Unsafe

When used orally due to the lack of toxicity information and its possible purgative action; avoid using.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

Bogbean & Breastfeeding

Possibly Unsafe

When used orally due to the lack of toxicity information and its possible purgative action; avoid using.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Bogbean monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Bogbean

4 brands in our database make a supplement containing Bogbean.

Pharmacist Counseling Corner

Bogbean: Common Questions

Does Bogbean interact with prescription medications?
We do not currently list any known drug interactions for Bogbean. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Bogbean interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Bogbean with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Bogbean interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Bogbean used for?
It is traditionally used as a bitter tonic to support appetite and digestion, and in folk medicine for joint and muscle pain such as arthritis. Strong scientific proof for these uses is lacking.
Is Bogbean safe to take?
In small traditional amounts it has generally been tolerated, but safety data are limited and large doses can cause nausea, vomiting, or diarrhea. People with ulcers, reflux, or bowel problems should be especially cautious and check with a healthcare professional first.
Can I use Bogbean while pregnant or breastfeeding?
No. There is not enough safety information, so it is best to avoid Bogbean during pregnancy and while breastfeeding.
Does Bogbean actually help arthritis?
It has a long history of traditional use for joint pain, but there is very little high-quality human research to show it truly works. It should not replace proven arthritis treatments.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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