Herb & supplement monograph

Latilactobacillus Sakei Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Latilactobacillus Sakei interacts with medications. The heart of this page is the interaction list — every drug Latilactobacillus Sakei is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Latilactobacillus Sakei is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Latilactobacillus Sakei Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated August 2026

Based on the available evidence, the overall risk of a clinically significant Latilactobacillus Sakei drug interaction appears low for most people, because the main concern is that certain medicines can weaken the probiotic itself rather than the other way around. None of the listed interactions are rated major, and every one of them traces back to a single, well-recognized issue with one class of medications.

Interactions deserving the most attention

The interaction that matters here involves antibiotics. Because Latilactobacillus sakei is a live, friendly bacteria, taking an antibiotic at the same time can kill many of the organisms and make the probiotic much less useful. This effect is graded as probable, meaning it has reasonable support, though it works in one direction: the antibiotic still does its job, but the probiotic may not. This is why the two are generally kept a couple of hours apart in practice.

What the rest of the list means

The long list of interacting medications looks bigger than it really is. Nearly all of those entries are simply individual antibiotics, so they reflect one shared concern repeated across many drug names, not many separate risks. For medicines outside the antibiotic group, no meaningful interactions have been identified in this profile.

Check your medications against Latilactobacillus Sakei

Based on HelloPharmacist’s Latilactobacillus Sakei interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Latilactobacillus Sakei

182 medications have a known interaction with Latilactobacillus Sakei, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AmikacinAmikin, Arikayce› AmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more› Amoxicillin VeterinaryBiomox› Amoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin› Amoxicillin, Omeprazole Magnesium, RifabutinTalicia› Amphotericin, TetracyclineMysteclin-F› AmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin› Ampicillin, SulbactamUnasyn› Avibactam Sodium, CeftazidimeAvycaz› AzithromycinAzasite, Zithromax, Zmax› AztreonamAzactam› BacampicillinPenglobe› BacitracinBaci-IM, Baciguent, Bacitracin Ointment› BenznidazoleBenznidazole› Bismuth Subsalicylate, Metronidazole, TetracyclineHelidac› CapreomycinCapastat› Carbenicillin Indanyl SodiumGeocillin› CefaclorCeclor, Ceclor CD› CefadroxilCef-Tab, Duricef, Ultracef› CefamandoleMandol› CefazolinAncef› CefdinirOmnicef› Cefditoren PivoxilSpectracef› CefepimeMaxipime› Cefiderocol Sulfate TosylateFetroja› CefiximeSuprax› CefmetazoleZefazone› CefonicidMonocid› CefoperazoneCefobid› CefotaximeClaforan›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Latilactobacillus Sakei combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Latilactobacillus Sakei affects

Every type of medication (drug category) Latilactobacillus Sakei is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 1 drug category Latilactobacillus Sakei interacts with
Antibiotic Drugs
Antibiotic Drugs

Theoretically, taking Latilactobacillus sakei with antibiotic drugs might decrease the effectiveness of L. sakei.
Latilactobacillus sakei preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. sakei preparations by at least two hours.

Likelihood Probable Evidence D
Monograph

Latilactobacillus Sakei: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Latilactobacillus sakei is a probiotic bacterium found in fermented foods like kimchi and certain meats, studied mostly for nasal sinus problems and eczema. Early research looks interesting, but evidence is still limited, so it should not replace proven treatments. Talk with a pharmacist or doctor before using it, especially if you have a weakened immune system.

Scientific name
Latilactobacillus sakei
Family
Lactobacillaceae
Part used
Whole bacterial cells (live or heat-killed)
Common forms
Capsules, powders, nasal sprays, topical creams, fermented foods (kimchi, fermented sausage)
People commonly use it for
  • Chronic rhinosinusitis and nasal congestion
  • Atopic dermatitis (eczema)
  • Allergies
  • Gut and immune support
  • Skin health

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally well tolerated in healthy people, but human safety data are limited.

PregnancyInsufficient reliable information

There is insufficient reliable information available about the safety of Latilactobacillus sakei during pregnancy and lactation. However, there are cu...

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

There is insufficient reliable information available about the safety of Latilactobacillus sakei during pregnancy and lactation. However, there are cu...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Latilactobacillus sakei (formerly called Lactobacillus sakei) is a type of friendly bacteria, or probiotic. It is best known for living in fermented foods, especially Korean kimchi and certain fermented meats and sausages, where it helps with the fermentation process.

Because it naturally grows in foods that many people eat, scientists have studied it as a possible health supplement. It is sold as capsules, powders, nasal sprays, and topical skin products. It can be used either as live bacteria or as heat-killed (inactivated) cells.

People most often look at this probiotic for nose and sinus problems and for skin conditions like eczema, though research is still in early stages.

How it works

Like other probiotics, Latilactobacillus sakei is thought to work by influencing the balance of microbes on the skin, in the gut, or in the nose. By competing with harmful bacteria, it may help keep unwanted germs from growing.

Laboratory and animal studies suggest it may also interact with the immune system, possibly calming down some inflammatory responses. This is one reason researchers are exploring it for allergy- and inflammation-related conditions like eczema and sinusitis.

It is important to know that much of this is based on lab and animal research, and the exact way it works in people is not fully understood. Effects can also differ from one strain to another.

Effectiveness

Does Latilactobacillus Sakei work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 3 uses evaluated
3 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Latilactobacillus Sakei, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 3 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Atopic dermatitis (eczema)
Rating & evidence shown verbatim from Natural Medicines

Most research shows that oral Latilactobacillus sakei is beneficial for reducing the overall severity of atopic dermatitis; further research is needed to confirm these findings.

Insufficient Reliable Evidence To Rate Dry eye
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral Latilactobacillus sakei or topical L. sakei lysate eye drops are beneficial in patients with dry eye.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral Latilactobacillus sakei is beneficial in adults with overweight or obesity.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

For most healthy people, probiotics like Latilactobacillus sakei are generally considered well tolerated, and the bacteria are commonly eaten in fermented foods. However, human safety data on supplement forms are limited.

People who should be cautious or avoid probiotic supplements include those with weakened immune systems, serious illness, central venous catheters, or those who are critically ill. In rare cases, live probiotics have been linked to serious infections in these high-risk groups.

For pregnancy and breastfeeding, there is not enough reliable safety information. Eating normal amounts of fermented foods is generally considered fine, but concentrated supplements should be avoided unless your doctor approves.

Always check with a pharmacist or doctor before starting any new supplement, especially if you have a medical condition or take medication.

Side effects

When side effects happen, they are usually mild. The most common ones with oral probiotics are digestive, such as gas, bloating, or an upset stomach. These often ease as the body adjusts.

Nasal or topical products may cause mild local irritation in some people.

Rarely, in people with weakened immune systems or serious health problems, live probiotic bacteria can cause more serious infections. If you develop fever, severe symptoms, or signs of infection while using a probiotic, stop and seek medical care.

Latilactobacillus Sakei: Reported Adverse Effects

Documented safety reports on Latilactobacillus Sakei from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Reports by condition
Sepsis Immunologic

Since Latilactobacillus sakei preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis. Most of these cases are thought to be due to the translocation of bacteria from other locations in the body in which they occur naturally, such as the oral cavity and gastrointestinal tract, and not to dietary or supplemental intake.

  1. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no standard, well-established dose for Latilactobacillus sakei. Probiotic amounts are usually measured in CFUs (colony-forming units), and the right amount can vary by product, strain, and intended use.

Because doses differ so much between products, the best advice is to follow the directions on the label of the specific product you buy. Do not assume more is better.

A pharmacist can help you choose a reputable product and review whether it is appropriate for you. If you are using it for a specific health problem, talk with your doctor first.

Pregnancy & Breastfeeding

Latilactobacillus Sakei & Pregnancy

Insufficient reliable information

There is insufficient reliable information available about the safety of Latilactobacillus sakei during pregnancy and lactation. However, there are currently no reasons to expect safety concerns when used appropriately.

Latilactobacillus Sakei & Breastfeeding

Insufficient reliable information

There is insufficient reliable information available about the safety of Latilactobacillus sakei during pregnancy and lactation. However, there are currently no reasons to expect safety concerns when used appropriately.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 references that drive our Latilactobacillus Sakei monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Latilactobacillus Sakei: Common Questions

What is Latilactobacillus Sakei used for, and does it work?
People use Latilactobacillus Sakei for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Latilactobacillus Sakei interact with prescription medications?
Yes. We list 182 medications with a known interaction with Latilactobacillus Sakei. Use the checker above to see how Latilactobacillus Sakei interacts with a specific drug.
How are Latilactobacillus Sakei interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Latilactobacillus Sakei with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Latilactobacillus Sakei interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Latilactobacillus Sakei used for?
It is a probiotic studied mainly for sinus problems (chronic rhinosinusitis) and skin conditions like eczema. The evidence is still early, so it is not a proven treatment for these conditions.
Is Latilactobacillus Sakei found in food?
Yes. It naturally grows in fermented foods such as Korean kimchi and some fermented meats and sausages, where it helps the fermentation process.
Is it safe to take?
Most healthy people tolerate it well, but supplement safety data are limited. People with weakened immune systems or serious illness should be cautious and check with a doctor first.
Can I take it while pregnant or breastfeeding?
There is not enough reliable safety information for supplement forms during pregnancy or breastfeeding, so it is best to avoid them unless your doctor approves.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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