Drug & supplement interaction

Latilactobacillus Sakei + Mepolizumab

Mepolizumab brand name: Nucala.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Latilactobacillus Sakei and Mepolizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Latilactobacillus Sakei and Mepolizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mepolizumab and Latilactobacillus Sakei in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Latilactobacillus Sakei safety at a glance

Latilactobacillus... overall Use caution Generally well tolerated in healthy people, but human safety data are limited.
Pregnancy Use caution Not enough safety data; avoid supplement forms unless cleared by your doctor.
Breastfeeding Use caution Not enough safety data; check with your doctor before using supplements.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mepolizumab and Latilactobacillus Sakei? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Latilactobacillus Sakei Does Interact With Other Medications

Latilactobacillus Sakei has 182 moderate known drug interactions in our database — Mepolizumab isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Latilactobacillus Sakei

Covers the 2,830 medications we’ve checked against Latilactobacillus Sakei. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Latilactobacillus Sakei and Mepolizumab May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on reported in 9.4% of FDA reports for Mepolizumab Additional detail

    Latilactobacillus Sakei

    “Since Latilactobacillus sakei preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Latilactobacillus Sakei · Natural Medicines adverse-effect record, reported in sepsis.

    1 source cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

    Mepolizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Mepolizumab, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Mepolizumab come from the ADVERSE REACTIONS section of its FDA label; effects for Latilactobacillus Sakei come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 49,399 voluntary FDA FAERS reports for Mepolizumab that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How much people look this up

Where Latilactobacillus Sakei and Mepolizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Latilactobacillus Sakei
Steady interest

#1,262 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mepolizumab
Steady interest

#1,677 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Latilactobacillus Sakei reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Latilactobacillus Sakei and Mepolizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Latilactobacillus Sakei

What is Latilactobacillus Sakei?

  • Chronic rhinosinusitis and nasal congestion
  • Atopic dermatitis (eczema)
  • Allergies
  • Gut and immune support
  • Skin health

Latilactobacillus sakei is a probiotic bacterium found in fermented foods like kimchi and certain meats, studied mostly for nasal sinus problems and eczema. Early research looks interesting, but evidence is still limited, so it should not replace proven treatments. Talk with a pharmacist or doctor before using it, especially if you have a weakened immune system.

Latilactobacillus sakei · Lactobacillaceae · Whole bacterial cells (live or heat-killed) · Capsules, powders, nasal sprays, topical creams, fermented foods (kimchi, fermented sausage)

An interaction check asks whether these two react with each other — it does not ask whether Latilactobacillus Sakei is a good idea for someone in your situation. Here is what our Latilactobacillus Sakei record says about it on its own.

Latilactobacillus Sakei: dosing

There is no standard, well-established dose for Latilactobacillus sakei. Probiotic amounts are usually measured in CFUs (colony-forming units), and the right amount can vary by product, strain, and intended use.Because doses differ so much between products, the best advice is to follow the directions on the label of the specific product you buy. Do not assume more is better.A pharmacist can help you choose a reputable product and review whether it is appropriate for you.

From our Latilactobacillus Sakei monograph — the full record covers uses, side effects and every documented interaction.

Read the full Latilactobacillus Sakei monograph & all interactions
Medication

About Mepolizumab Injection

What Is Mepolizumab Injection Used For?

Brand name: Nucala

Nucala is used as an add-on maintenance treatment — meaning it works alongside other medications, not instead of them. It is approved for severe asthma (in patients 6 years and older with high eosinophil levels), chronic rhinosinusitis with nasal polyps (CRSwNP) in adults 18 and older whose symptoms aren't controlled by nasal corticosteroids alone, and COPD in adults with an eosinophilic phenotype whose disease isn't adequately controlled.

Nucala is also approved to treat eosinophilic granulomatosis with polyangiitis (EGPA), a rare form of blood vessel inflammation, and hypereosinophilic syndrome (HES), a condition involving dangerously elevated eosinophil counts, in adults and adolescents 12 and older. It is not meant to relieve sudden asthma attacks or acute COPD flares.

Most-Reported Side Effects for Mepolizumab

From FAERS, the FDA’s public side-effect reporting system (49,399 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Asthma 12,767 reports
Dyspnea 10,576 reports
Wheezing 7,131 reports
Cough 5,100 reports
Therapeutic product effect incomplete 5,051 reports
See full Mepolizumab Injection drug information
Keep checking

Other Drugs & Latilactobacillus Sakei

Browse every other medication we’ve checked against Latilactobacillus Sakei — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Latilactobacillus Sakei page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Latilactobacillus Sakei References

The 2 references that drive our Latilactobacillus Sakei monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Latilactobacillus Sakei and Mepolizumab Together: Common Questions

Is it safe to take Latilactobacillus Sakei with Mepolizumab?
We do not list a known interaction between Latilactobacillus Sakei and Mepolizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Latilactobacillus Sakei and Mepolizumab have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Latilactobacillus Sakei interact with any other medications?
Yes. Latilactobacillus Sakei has 182 documented drug interactions in our database — Mepolizumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Mepolizumab and Latilactobacillus Sakei?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.