Drug & supplement interaction

Latilactobacillus Sakei + Ranolazine

Ranolazine brand names: Ranexa, Aspruzyo.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Latilactobacillus Sakei and Ranolazine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Latilactobacillus Sakei and Ranolazine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ranolazine and Latilactobacillus Sakei in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Latilactobacillus Sakei safety at a glance

Latilactobacillus... overall Use caution Generally well tolerated in healthy people, but human safety data are limited.
Pregnancy Use caution Not enough safety data; avoid supplement forms unless cleared by your doctor.
Breastfeeding Use caution Not enough safety data; check with your doctor before using supplements.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ranolazine and Latilactobacillus Sakei? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ranolazine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ranolazine is filed under 5 classifications — including cytochrome p450 2d6 (cyp2d6) inhibitors, qt interval-prolonging drugs, p-glycoprotein substrates. Latilactobacillus Sakei has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Ranolazine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Latilactobacillus Sakei Does Interact With Other Medications

Latilactobacillus Sakei has 182 moderate known drug interactions in our database — Ranolazine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Latilactobacillus Sakei

Covers the 2,830 medications we’ve checked against Latilactobacillus Sakei. Pick one to open its full report.

What to actually watch for

What Latilactobacillus Sakei Itself Has Been Linked To

This is not an interaction — nothing below involves Ranolazine. It is the side-effect record for Latilactobacillus Sakei on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Latilactobacillus Sakei, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Latilactobacillus sakei preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Latilactobacillus Sakei · Natural Medicines adverse-effect record, reported in sepsis.

    1 source cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Latilactobacillus Sakei — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Ranolazine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Ranolazine column appears here.

Everything else you take

See Every Supplement That Interacts With Ranolazine

This page covers Latilactobacillus Sakei only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ranolazine page lists 153 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 109 moderate · 36 minor.

From our pharmacist’s overview on the Ranolazine page

“Ranolazine (Ranexa, Aspruzyo), a medicine for chronic chest pain, depends heavily on one liver enzyme, CYP3A4, and that is where most of its supplement trouble sits. Grapefruit can push ranolazine levels up, St.”

Reviewed by 2 · Jul 18, 2026

Open the Ranolazine interaction page

How much people look this up

Where Latilactobacillus Sakei and Ranolazine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Latilactobacillus Sakei
Top half

#683 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ranolazine
Top 25%

#619 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Latilactobacillus Sakei reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Latilactobacillus Sakei and Ranolazine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Latilactobacillus Sakei

What is Latilactobacillus Sakei?

  • Chronic rhinosinusitis and nasal congestion
  • Atopic dermatitis (eczema)
  • Allergies
  • Gut and immune support
  • Skin health

Latilactobacillus sakei is a probiotic bacterium found in fermented foods like kimchi and certain meats, studied mostly for nasal sinus problems and eczema. Early research looks interesting, but evidence is still limited, so it should not replace proven treatments. Talk with a pharmacist or doctor before using it, especially if you have a weakened immune system.

Latilactobacillus sakei · Lactobacillaceae · Whole bacterial cells (live or heat-killed) · Capsules, powders, nasal sprays, topical creams, fermented foods (kimchi, fermented sausage)

An interaction check asks whether these two react with each other — it does not ask whether Latilactobacillus Sakei is a good idea for someone in your situation. Here is what our Latilactobacillus Sakei record says about it on its own.

Latilactobacillus Sakei: dosing

There is no standard, well-established dose for Latilactobacillus sakei. Probiotic amounts are usually measured in CFUs (colony-forming units), and the right amount can vary by product, strain, and intended use.Because doses differ so much between products, the best advice is to follow the directions on the label of the specific product you buy. Do not assume more is better.A pharmacist can help you choose a reputable product and review whether it is appropriate for you.

From our Latilactobacillus Sakei monograph — the full record covers uses, side effects and every documented interaction.

Read the full Latilactobacillus Sakei monograph & all interactions
Medication

About Ranolazine

What Is Ranolazine Used For?

Brand names: Ranexa, Aspruzyo

Ranolazine treats chronic angina — the recurring chest pain or pressure that happens when the heart isn't getting enough blood and oxygen. It is used when other angina medicines aren't enough on their own.

Both the extended-release tablet (sold as Ranexa and generic ranolazine) and the oral powder form (sold as Aspruzyo Sprinkle) are approved for this use. Ranolazine can be combined with other heart medicines such as beta-blockers, nitrates, calcium channel blockers, anti-platelet drugs, statins, ACE inhibitors, and angiotensin receptor blockers.

Most-Reported Side Effects for Ranolazine

From FAERS, the FDA’s public side-effect reporting system (10,376 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Myocardial infarction 646 reports
Chest pain 614 reports
Angina pectoris 595 reports
Stent placement 582 reports
Dyspnea 439 reports
See full Ranolazine drug information
Keep checking

Other Drugs & Latilactobacillus Sakei

Browse every other medication we’ve checked against Latilactobacillus Sakei — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Latilactobacillus Sakei page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Latilactobacillus Sakei References

The 2 references that drive our Latilactobacillus Sakei monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Latilactobacillus Sakei and Ranolazine Together: Common Questions

Is it safe to take Latilactobacillus Sakei with Ranolazine?
We do not list a known interaction between Latilactobacillus Sakei and Ranolazine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Latilactobacillus Sakei and Ranolazine combination checked?
Interactions in our licensed database are recorded against drug classes. Ranolazine is filed under 5 classifications, and Latilactobacillus Sakei has documented interactions with 1 drug class — none of Ranolazine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Latilactobacillus Sakei interact with any other medications?
Yes. Latilactobacillus Sakei has 182 documented drug interactions in our database — Ranolazine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ranolazine interact with any supplements?
Yes. Ranolazine has documented interactions with 153 supplements in our database — Latilactobacillus Sakei is not one of them. The Ranolazine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ranolazine and Latilactobacillus Sakei?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.