Drug & supplement interaction

Latilactobacillus Sakei + Phenylephrine

Phenylephrine brand names: Gilchew, AH Chew D, Gilchew IR, Sudafed PE, Biorphen.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Latilactobacillus Sakei and Phenylephrine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Latilactobacillus Sakei and Phenylephrine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Phenylephrine and Latilactobacillus Sakei in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Latilactobacillus Sakei safety at a glance

Latilactobacillus... overall Use caution Generally well tolerated in healthy people, but human safety data are limited.
Pregnancy Use caution Not enough safety data; avoid supplement forms unless cleared by your doctor.
Breastfeeding Use caution Not enough safety data; check with your doctor before using supplements.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Phenylephrine and Latilactobacillus Sakei? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Phenylephrine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Phenylephrine is filed under 5 classifications — including alpha-adrenergic agonists, stimulant drugs, serotonergic drugs. Latilactobacillus Sakei has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Phenylephrine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Latilactobacillus Sakei Does Interact With Other Medications

Latilactobacillus Sakei has 182 moderate known drug interactions in our database — Phenylephrine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Latilactobacillus Sakei

Covers the 2,830 medications we’ve checked against Latilactobacillus Sakei. Pick one to open its full report.

What to actually watch for

What Latilactobacillus Sakei Itself Has Been Linked To

This is not an interaction — nothing below involves Phenylephrine. It is the side-effect record for Latilactobacillus Sakei on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Latilactobacillus Sakei, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Latilactobacillus sakei preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Latilactobacillus Sakei · Natural Medicines adverse-effect record, reported in sepsis.

    1 source cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Latilactobacillus Sakei — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Phenylephrine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Phenylephrine column appears here.

From our Q&A

Questions About Latilactobacillus Sakei or Phenylephrine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Latilactobacillus Sakei or Phenylephrine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Phenylephrine

This page covers Latilactobacillus Sakei only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Phenylephrine page lists 81 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Lithium (major), Peyote (major) and Rauvolfia Vomitoria (major).

By severity: 6 major · 60 moderate · 15 minor.

From our pharmacist’s overview on the Phenylephrine page

“If you take phenylephrine (Sudafed PE, Biorphen) for congestion, treat this list as one that needs real attention, since six of its 81 entries carry a major rating. Phenylephrine tightens blood vessels to clear your nose, and more than half of the interactions here come from stimulant ingredients, ephedra above all, that can push blood…”

Reviewed by 2 · Jul 18, 2026

Open the Phenylephrine interaction page

How much people look this up

Where Latilactobacillus Sakei and Phenylephrine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Latilactobacillus Sakei
Steady interest

#1,255 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Phenylephrine
Top 25%

#566 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Latilactobacillus Sakei reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Latilactobacillus Sakei and Phenylephrine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Latilactobacillus Sakei

What is Latilactobacillus Sakei?

  • Chronic rhinosinusitis and nasal congestion
  • Atopic dermatitis (eczema)
  • Allergies
  • Gut and immune support
  • Skin health

Latilactobacillus sakei is a probiotic bacterium found in fermented foods like kimchi and certain meats, studied mostly for nasal sinus problems and eczema. Early research looks interesting, but evidence is still limited, so it should not replace proven treatments. Talk with a pharmacist or doctor before using it, especially if you have a weakened immune system.

Latilactobacillus sakei · Lactobacillaceae · Whole bacterial cells (live or heat-killed) · Capsules, powders, nasal sprays, topical creams, fermented foods (kimchi, fermented sausage)

An interaction check asks whether these two react with each other — it does not ask whether Latilactobacillus Sakei is a good idea for someone in your situation. Here is what our Latilactobacillus Sakei record says about it on its own.

Latilactobacillus Sakei: dosing

There is no standard, well-established dose for Latilactobacillus sakei. Probiotic amounts are usually measured in CFUs (colony-forming units), and the right amount can vary by product, strain, and intended use.Because doses differ so much between products, the best advice is to follow the directions on the label of the specific product you buy. Do not assume more is better.A pharmacist can help you choose a reputable product and review whether it is appropriate for you.

From our Latilactobacillus Sakei monograph — the full record covers uses, side effects and every documented interaction.

Read the full Latilactobacillus Sakei monograph & all interactions
Medication

About Phenylephrine

What Is Phenylephrine Used For?

Brand names: Gilchew, AH Chew D, Gilchew IR, Sudafed PE, Biorphen

Phenylephrine is used in several different products, and each one has its own use.

Injection (IV): raises blood pressure in adults with clinically important hypotension (low blood pressure) caused mainly by widened blood vessels. Some injections are labeled for anesthesia only. Others are labeled for anesthesia and septic shock.

Eye drops: Phenylephrine Hydrochloride Ophthalmic Solution is used to dilate the pupil.

Nasal products: temporarily relieve nasal and sinus congestion from the common cold, hay fever or other upper respiratory allergies.

Rectal suppositories: relieve itching, burning and discomfort from hemorrhoids and temporarily shrink hemorrhoidal tissue.

Most-Reported Side Effects for Phenylephrine

From FAERS, the FDA’s public side-effect reporting system (221,388 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 20,609 reports
Headache 17,301 reports
Nausea 16,925 reports
Diarrhea 14,221 reports
Dyspnea 13,719 reports
See full Phenylephrine drug information
Keep checking

Other Drugs & Latilactobacillus Sakei

Browse every other medication we’ve checked against Latilactobacillus Sakei — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Latilactobacillus Sakei page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Latilactobacillus Sakei References

The 2 references that drive our Latilactobacillus Sakei monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Latilactobacillus Sakei and Phenylephrine Together: Common Questions

Is it safe to take Latilactobacillus Sakei with Phenylephrine?
We do not list a known interaction between Latilactobacillus Sakei and Phenylephrine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Latilactobacillus Sakei and Phenylephrine combination checked?
Interactions in our licensed database are recorded against drug classes. Phenylephrine is filed under 5 classifications, and Latilactobacillus Sakei has documented interactions with 1 drug class — none of Phenylephrine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Latilactobacillus Sakei interact with any other medications?
Yes. Latilactobacillus Sakei has 182 documented drug interactions in our database — Phenylephrine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Phenylephrine interact with any supplements?
Yes. Phenylephrine has documented interactions with 81 supplements in our database — Latilactobacillus Sakei is not one of them. The Phenylephrine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Phenylephrine and Latilactobacillus Sakei?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.