Herb & supplement monograph

Levilactobacillus Brevis Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated July 2026

What is this page for?

First and foremost: how Levilactobacillus Brevis interacts with medications. The heart of this page is the interaction list — every drug Levilactobacillus Brevis is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Levilactobacillus Brevis is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

Check Levilactobacillus Brevis against your medication

Add one medication

✓ Supplement

Levilactobacillus Brevis

1 Your medication

Start typing any prescription or over-the-counter drug name.

Reviewed by licensed pharmacists Sourced from Natural Medicines

On this page

Levilactobacillus Brevis Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated August 2026

Based on the available evidence, the overall risk of a clinically significant Levilactobacillus Brevis drug interaction is low for most people, because the main concern is a weaker probiotic effect rather than harm from the medication. None of the listed interactions are rated major, and the entire profile comes down to a single, well-understood issue involving one class of drugs.

Interactions deserving the most attention

The one combination worth attention is antibiotics. Because Levilactobacillus brevis is a live, friendly bacteria, an antibiotic taken at the same time can kill many of the organisms and blunt the probiotic's benefit. This does not make the antibiotic less effective or dangerous, and the supporting evidence, while reasonable, is still largely theoretical rather than proven in careful human studies.

What the rest of the list means

The long list of interacting medications looks bigger than it really is. Every entry reflects the same single mechanism applied across many individual antibiotic products, not many separate risks. Nothing in the data suggests this probiotic changes how the body handles other medicines or raises safety concerns like bleeding, blood sugar, or drug levels.

Check your medications against Levilactobacillus Brevis

Based on HelloPharmacist’s Levilactobacillus Brevis interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Levilactobacillus Brevis

182 medications have a known interaction with Levilactobacillus Brevis, graded by severity. Select any drug for the full evidence-based detail.

Don’t want to scroll the list? Just ask.

Tell us the medications you take and we’ll check each one against Levilactobacillus Brevis using our pharmacist-reviewed interaction data.

AI summaries are generated from our Levilactobacillus Brevis interaction data for education only — always confirm with your pharmacist. How we use AI

2,830 drugs

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
Each drug listed above links to the full report for that exact Levilactobacillus Brevis combination — clinical detail, likelihood, evidence level, and citations.
Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

The big picture

The kinds of drugs Levilactobacillus Brevis affects

Every type of medication (drug category) Levilactobacillus Brevis is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 1 drug category Levilactobacillus Brevis interacts with

Antibiotic Drugs

Theoretically, taking Levilactobacillus brevis with antibiotic drugs might decrease the effectiveness of L. brevis.
Levilactobacillus brevis preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. brevis preparations by at least two hours.

Likelihood Probable Evidence D

Monograph

Levilactobacillus Brevis: Uses, Safety & Side Effects

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Reviewed July 2026 ·

The bottom line

Levilactobacillus brevis (formerly Lactobacillus brevis) is a lactic acid bacterium found in fermented foods like sauerkraut, pickles, and kimchi, and is used as a probiotic. Early research suggests possible benefits for gut and immune health, but strong human evidence is still limited. It is generally well tolerated in healthy people, but anyone with a weakened immune system or serious illness should talk to a doctor first.

Scientific name: Levilactobacillus brevis
Family: Lactobacillaceae
Part used: Whole live bacteria (probiotic strain)
Common forms: Capsules, tablets, powders, fermented foods, and combination probiotic products

People commonly use it for

Digestive health
Gut microbiome support
Immune support
Oral and dental health
Vaginal health

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance

OverallUse caution

Generally well tolerated in healthy people, but people who are seriously ill or immunocompromised should be cautious.

PregnancyInsufficient reliable information

There is insufficient reliable information available about the safety of Levilactobacillus brevis during pregnancy and lactation. However, there are c...

Read the full pregnancy detail

BreastfeedingInsufficient reliable information

There is insufficient reliable information available about the safety of Levilactobacillus brevis during pregnancy and lactation. However, there are c...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Levilactobacillus brevis is a type of friendly bacteria. It was previously called Lactobacillus brevis, but scientists renamed it. It belongs to a large group of bacteria called lactic acid bacteria, which produce lactic acid as they grow.

This bacterium is found naturally in many fermented foods. You may eat it without knowing in sauerkraut, pickles, kimchi, certain cheeses, and some types of beer and sourdough. It also lives in the human gut and mouth.

Because it can survive in the gut and produce helpful substances, it is sold as a probiotic. People take it alone or as part of a blend of probiotic strains to support digestion and overall gut health.

How it works

Like other probiotics, Levilactobacillus brevis is thought to work by adding helpful bacteria to the gut. This may help keep a healthy balance between good and harmful microbes.

In laboratory and animal studies, this bacterium can produce lactic acid and other compounds that may make the gut environment less friendly to harmful bacteria. Some strains may also help strengthen the gut lining and interact with the immune system in ways that may calm inflammation.

It is important to remember that much of this is based on laboratory and animal research. How strongly these effects happen in the human body is still being studied.

Effectiveness

Does Levilactobacillus Brevis work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by Dr. Brian Staiger, PharmD.

Evidence overview · 19 uses evaluated

19 Insufficient evidence

How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.

2Likely EffectiveGood evidence, though not yet conclusive.

3Possibly EffectiveSome evidence suggests a benefit.

4Possibly IneffectiveSome evidence it may not help.

5Likely IneffectiveFairly strong evidence it doesn’t help.

6IneffectiveStrong evidence it doesn’t work.

7Insufficient Reliable Evidence to RateToo little research to say either way.

For Levilactobacillus Brevis, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 19 conditions — evidence insufficient to rate

Insufficient Reliable Evidence To Rate Alcohol-related liver disease