Herb & supplement monograph

Durabolin Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Durabolin

0 medications have a known interaction with Durabolin, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Durabolin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Durabolin combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Durabolin: Uses, Safety & Side Effects

The bottom line

Durabolin is a brand name for nandrolone, a prescription anabolic steroid (a synthetic form of testosterone) — it is not a dietary supplement or herb. It is a controlled medicine with serious risks and should only ever be used under a doctor's supervision, never bought or used on your own for muscle building.

Part used
Not applicable — Durabolin is a manufactured drug, not a plant or supplement
Common forms
Injectable solution (prescription medicine)
People commonly use it for
  • Building muscle (anabolic steroid use)
  • Certain anemias
  • Some forms of muscle wasting
  • Bodybuilding and athletic performance (non-medical use)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallBest avoided

This is a controlled anabolic steroid drug, not a supplement, and should only be used if prescribed and monitored by a doctor.

PregnancyPossibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including red...

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including red...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Durabolin is not a dietary supplement or herb. It is a brand name for nandrolone (specifically nandrolone phenylpropionate), a man-made anabolic steroid. Anabolic steroids are lab-made versions of the male hormone testosterone.

Durabolin is a prescription drug that is given as an injection. In medicine, related nandrolone products have been used for certain types of anemia and other conditions where the body is breaking down muscle. Because we focus on supplements and herbs here, it is important to know that Durabolin does not belong in that category.

Outside of medical use, nandrolone is sometimes used illegally by athletes and bodybuilders to build muscle and boost performance. This use is not safe, is often illegal, and is banned in sports.

Uses & effectiveness

As a prescription drug, nandrolone has been used by doctors for select medical reasons, such as certain anemias and muscle-wasting problems. In those settings it is used under close medical supervision.

Many people look up Durabolin because it is used (often without a prescription) to increase muscle size and strength. While anabolic steroids can increase muscle mass, this non-medical use carries serious health and legal risks and is not endorsed by health authorities. It is not a safe or approved way to improve fitness or appearance.

There is no role for Durabolin as a self-care supplement, and it should never be treated like an over-the-counter product.

How it works

Nandrolone is an anabolic-androgenic steroid. It is similar in structure to testosterone. It attaches to androgen receptors in the body, which can increase protein building in muscle and stimulate red blood cell production.

Because it acts like a powerful hormone, it also affects many other systems in the body, including the heart, liver, cholesterol levels, mood, and the body's own natural hormone production. These wide-ranging effects are why it can cause serious side effects.

Safety & precautions

Durabolin is a powerful hormone drug and a controlled substance in many countries. It should only be used when prescribed and monitored by a healthcare provider.

People with prostate or breast cancer, serious heart problems, liver disease, kidney disease, or high calcium levels should generally not use it. Men and women can both develop hormone-related problems with use.

Pregnancy: Avoid completely. Anabolic steroids can cause harm to a developing baby. Breastfeeding: Avoid. These drugs are not considered safe while nursing. If you are pregnant, breastfeeding, or trying to conceive, do not use this drug.

Never buy nandrolone from unregulated online sources or gyms. Such products may be contaminated, mislabeled, or fake, adding even more risk.

Side effects

Anabolic steroids like nandrolone can cause many side effects. These may include acne, oily skin, fluid retention, mood changes (including aggression or depression), and changes in cholesterol.

In men, it can shrink the testicles, lower natural testosterone, reduce sperm count, and cause breast tissue growth. In women, it can cause deepening of the voice, facial hair, irregular periods, and other masculinizing effects that may be permanent.

More serious risks include liver problems, increased risk of heart disease and blood clots, high blood pressure, and harmful effects on the heart. Long-term or high-dose misuse can be especially dangerous.

Dosing

There is no supplement-style dose for Durabolin because it is a prescription medicine, not a supplement. Any dose must be decided by a doctor based on the specific medical condition being treated.

Do not try to dose this drug on your own. If a doctor has prescribed nandrolone for you, follow their exact instructions and keep all monitoring appointments. If you have questions, ask your pharmacist or prescriber.

Pregnancy & Breastfeeding

Durabolin & Pregnancy

Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.

Durabolin & Breastfeeding

Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Durabolin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Durabolin

2 brands in our database make a supplement containing Durabolin.

Pharmacist Counseling Corner

Durabolin: Common Questions

Does Durabolin interact with prescription medications?
We do not currently list any known drug interactions for Durabolin. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Durabolin interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Durabolin with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Durabolin interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Durabolin a natural supplement or herb?
No. Durabolin is a brand name for nandrolone, a man-made anabolic steroid and prescription drug. It is not a supplement, vitamin, or herb.
Can I buy Durabolin to build muscle?
Using nandrolone to build muscle without a prescription is unsafe and illegal in many places. It can cause serious heart, liver, hormone, and mental health problems, so it should never be used this way.
Is Durabolin safe during pregnancy or breastfeeding?
No. Anabolic steroids can harm an unborn baby and should not be used during pregnancy or while breastfeeding.
What are the most serious risks of Durabolin?
Serious risks include heart disease, blood clots, liver damage, high blood pressure, hormone disruption, and mood changes. Women may also develop permanent masculinizing effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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