Herb & supplement monograph

Marsh Blazing Star Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Marsh Blazing Star

0 medications have a known interaction with Marsh Blazing Star, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Marsh Blazing Star. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Marsh Blazing Star combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Marsh Blazing Star: Uses, Safety & Side Effects

The bottom line

Marsh blazing star (Liatris spicata) is a North American prairie plant whose root has a long history in folk medicine for urinary, menstrual, and digestive complaints. There is very little modern scientific evidence to confirm that it works or to define a safe dose, so it should be used cautiously and avoided in pregnancy and breastfeeding.

Marsh Blazing Star
Scientific name
Liatris spicata
Family
Asteraceae
Part used
Root
Common forms
Dried root, tea, tincture, capsules
People commonly use it for
  • Kidney and urinary complaints
  • Menstrual cramps (dysmenorrhea)
  • As a diuretic
  • Colic and digestive upset
  • Sore throat (traditional gargle)

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLimited data

There is not enough reliable human research to judge its safety.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Marsh blazing star (Liatris spicata) is a tall, upright perennial plant in the aster family (Asteraceae). It is native to eastern and central North America, where it grows in moist prairies, meadows, and marshy areas. In summer it produces striking spikes of fluffy, deep purple flower heads, which is why it is often called "blazing star" or "gay-feather." It is also widely grown as an ornamental garden plant.

In traditional and folk medicine, the part used is the root. It has been used by various groups for urinary and kidney complaints, menstrual cramps, sore throats, and digestive problems. Today it is sometimes sold as a dried root, tea, tincture, or capsule, though it is far more common as a garden flower than as a supplement.

Uses & effectiveness

People have traditionally used marsh blazing star root for kidney and bladder problems, as a diuretic (to increase urine flow), for painful menstrual periods, for colic and digestive upset, and as a gargle for sore throat. Historically it was also used for conditions such as gonorrhea before modern medicine existed.

The evidence for these uses is very weak. There are essentially no good-quality human clinical trials showing that marsh blazing star treats any condition. Most of what is known comes from traditional use and a small amount of laboratory study of its chemical makeup. Because of this, it is not possible to say that it is effective for any health problem. If you are dealing with a urinary infection, kidney issue, or severe menstrual pain, you should see a healthcare provider rather than rely on this herb.

How it works

The root contains coumarin and other plant compounds. Coumarins are naturally occurring substances found in many plants. Some plant coumarins have been studied for effects on blood vessels and fluid balance, which may explain the traditional use as a diuretic, but this has not been confirmed for marsh blazing star specifically.

Like many members of the aster family, the plant also contains a mix of other natural compounds that may have mild antioxidant or antimicrobial activity in the laboratory. It is important to understand that these are mostly test-tube observations. They do not prove that the herb produces meaningful effects in the human body or that it is safe at any particular dose.

Safety & precautions

There is very little modern safety information on marsh blazing star, so its overall safety is considered unknown. Because the root contains coumarin and other active compounds, it is best treated with caution.

People who should be especially careful include those with kidney disease, those who are allergic to plants in the aster/daisy family (such as ragweed, marigolds, and chrysanthemums), and anyone with a bleeding disorder. Pregnant and breastfeeding people should avoid it because of its traditional use related to menstruation and the complete lack of safety data. Always talk with a pharmacist or doctor before trying this or any new herbal product, and do not give it to children.

Side effects

Because marsh blazing star has not been well studied in people, its side effect profile is not well defined. Based on its diuretic reputation, it could in theory increase urination. Plants in the aster family can cause allergic reactions, especially in people sensitive to ragweed and related plants.

As with many herbal products, possible effects include stomach upset, nausea, or skin reactions. Stop using it and seek medical care if you notice signs of an allergic reaction such as rash, itching, swelling, or trouble breathing.

Marsh Blazing Star: Reported Adverse Effects

Documented safety reports on Marsh Blazing Star from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, marsh blazing star, which contains coumarin, can be associated with nausea and vomiting, diarrhea, dizziness, insomnia, asymptomatic SGOT elevations, and liver toxicity.

Topically, handling the plant can cause contact dermatitis.

Marsh blazing star can cause an allergic reaction in individuals sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many other herbs.

  1. Mohler JL, Gomella LG, Crawford ED, et al. Phase II evaluation of coumarin (1,2-benzopyrone) in metastatic prostatic carcinoma. Prostate 1992;20:123-31.
  2. Marshall ME, Butler K, Fried A. Phase I evaluation of coumarin (1,2 benzopyrone) and cimetidine in patients with advanced malignancies. Mol Biother 1991;3:170-8.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Goerz G, Wirth G, Maas B, et al. [Allergic contact dermatitis due to Asteraceae (Compositae). Cross reaction with Liatris spicata]. Derm Beruf Umwelt 1985;33:95-8.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established or standardized dose for marsh blazing star. Traditional preparations used the dried root as a tea or tincture, but no reliable amount has been confirmed as safe or effective in modern research.

If you choose to use a commercial product, follow the directions on the label and do not exceed them. Because the quality and strength of herbal supplements can vary widely, talk with a pharmacist or doctor first, especially if you take other medicines or have a health condition.

Pregnancy & Breastfeeding

Marsh Blazing Star & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Marsh Blazing Star & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 5 references that drive our Marsh Blazing Star monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Mohler JL, Gomella LG, Crawford ED, et al. Phase II evaluation of coumarin (1,2-benzopyrone) in metastatic prostatic carcinoma. Prostate 1992;20:123-31. PubMed
  4. Marshall ME, Butler K, Fried A. Phase I evaluation of coumarin (1,2 benzopyrone) and cimetidine in patients with advanced malignancies. Mol Biother 1991;3:170-8.
  5. Goerz G, Wirth G, Maas B, et al. [Allergic contact dermatitis due to Asteraceae (Compositae). Cross reaction with Liatris spicata]. Derm Beruf Umwelt 1985;33:95-8.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Marsh Blazing Star: Common Questions

Does Marsh Blazing Star interact with prescription medications?
We do not currently list any known drug interactions for Marsh Blazing Star. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Marsh Blazing Star interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Marsh Blazing Star with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Marsh Blazing Star interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Marsh Blazing Star used for?
Traditionally, its root has been used for kidney and urinary complaints, as a diuretic, for menstrual cramps, and for digestive upset. There is little scientific evidence proving it works for any of these.
Is Marsh Blazing Star safe to take?
Its safety has not been well studied in people, so it is best used with caution. Talk to a pharmacist or doctor before trying it, especially if you have kidney problems or allergies to ragweed and related plants.
Can I take it during pregnancy or while breastfeeding?
No. It is best to avoid Marsh Blazing Star during pregnancy and breastfeeding because there is no safety data and it has traditionally been used in ways that may affect menstruation.
Is Marsh Blazing Star the same plant grown in gardens?
Yes, Liatris spicata is a popular ornamental garden plant valued for its purple flower spikes. The medicinal preparations come from the root of the same plant.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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