Nasturtium Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Nasturtium interacts with medications. The heart of this page is the interaction list — every drug Nasturtium is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Nasturtium is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Nasturtium against your medication
Add one medicationDrugs that interact with Nasturtium
0 medications have a known interaction with Nasturtium, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Nasturtium. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Nasturtium combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Nasturtium: Uses, Safety & Side Effects
Nasturtium is an edible garden plant traditionally used for urinary and respiratory infections, often combined with horseradish in herbal products. Some lab studies suggest it has antimicrobial activity, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have kidney or stomach problems.
- Scientific name
- Tropaeolum majus
- Family
- Tropaeolaceae
- Part used
- Leaves, flowers, and seeds
- Common forms
- Fresh leaves and flowers (food/salad), dried herb, tea, capsules, tinctures, and combination herbal products
- Urinary tract infections
- Respiratory infections and congestion
- Antimicrobial support
- Wound and skin care (topical)
- Mild cold and cough symptoms
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally considered safe as a food, but concentrated extracts have limited safety data.
Insufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.
Read the full pregnancy detailInsufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Nasturtium (Tropaeolum majus) is a flowering plant native to South America that is now grown in gardens around the world. It is popular as an ornamental plant, and its colorful flowers and peppery-tasting leaves are also used in cooking and salads.
Beyond food, nasturtium has a long history in traditional and folk medicine. People have used its leaves, flowers, and seeds for urinary and respiratory complaints and as a natural antimicrobial. In some countries, nasturtium is combined with horseradish in herbal products marketed for infections of the urinary and respiratory tracts.
How it works
Nasturtium is rich in compounds called glucosinolates, which break down into substances known as isothiocyanates (including benzyl isothiocyanate). These are the same family of compounds that give the plant its sharp, peppery taste.
In laboratory studies, these isothiocyanates appear to have antimicrobial activity against some bacteria and fungi. The plant also contains vitamin C and antioxidant compounds. It is important to know that most of this research is based on lab or animal studies, so it does not necessarily mean the same effects happen in the human body.
Does Nasturtium work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Nasturtium, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Respiratory tract infections
Preliminary clinical research in patients with a history of recurrent respiratory tract infections (RTIs) shows that taking a specific combination product (Angocin Anti-Infekt N, Repha GmbH) containing a total of 320-400 mg horseradish root and 800-1000 mg nasturtium daily for 12 weeks modestly decreases the rate of new RTIs when compared with placebo. However, there were no differences between groups in time to infection, intensity or duration of infection, or rates of specific infections, including acute rhinopharyngitis, sinusitis, laryngitis, or tracheitis. Also, it is not clear if this effect is due to nasturtium, horseradish, or the combination.
Insufficient Reliable Evidence To Rate Urinary tract infections (UTIs)
A small clinical study in patients with recurrent UTIs shows that taking a specific product (Angocin Anti-Infekt N, Repha GmbH) containing a total of 320 mg horseradish root and 800 mg nasturtium daily for 90 days modestly reduces the recurrence of UTIs when compared with placebo at 3 months after treatment completion, but not at the time of treatment completion. However, this analysis excluded patients that were not cured from their initial active UTI. Additionally, the small size, short duration, and high dropout rate in this study limits the validity of these findings. Furthermore, it is not clear if this effect is due to nasturtium, horseradish, or the combination.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
When eaten in normal food amounts, nasturtium leaves and flowers are generally considered safe for most people. The safety of concentrated extracts, capsules, and long-term medicinal use is less well studied.
People with stomach or intestinal ulcers or kidney problems should be cautious, since the plant's pungent compounds may irritate these areas. Children and people with sensitive stomachs should also use caution.
For pregnancy, there is not enough reliable safety information, so medicinal amounts should be avoided. For breastfeeding, safety is also unclear, so it is best to be cautious or avoid concentrated products. Always check with your pharmacist or doctor before starting nasturtium, especially if you take other medicines or have a health condition.
Side effects
Nasturtium is usually well tolerated as a food. When taken in larger or concentrated amounts, possible side effects include stomach upset, heartburn, or irritation of the digestive tract because of its spicy isothiocyanate compounds.
Some people may have an allergic reaction or skin irritation, especially when it is applied to the skin. Stop using it and seek medical care if you notice swelling, trouble breathing, or a severe rash.
Nasturtium: Reported Adverse Effects
Documented safety reports on Nasturtium from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, large amounts of nasturtium or benzyl mustard oil, a constituent of nasturtium, can cause gastrointestinal tract irritation. Large amounts of nasturtium can cause albuminuria due to glomerular and tubular damage.
Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation. Benzyl mustard oil is a contact allergen if applied to the skin; case reports of contact dermatitis have been attributed to the nasturtium plant.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30.
Albuminuria Renal
Orally, large amounts of nasturtium can cause albuminuria due to glomerular and tubular damage.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
Dermatitis Dermatologic
Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation. Benzyl mustard oil is a contact allergen if applied to the skin. There are multiple case reports of contact dermatitis attributed to nasturtium.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established standardized dose for nasturtium. Amounts vary widely depending on whether you use fresh leaves, dried herb, tea, capsules, or a combination product.
The best approach is to follow the directions on the product label and not exceed the recommended amount. Because product strengths differ and reliable dosing research is lacking, check with your pharmacist or doctor before using nasturtium as a supplement.
Nasturtium & Pregnancy
Nasturtium & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 5 references that drive our Nasturtium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Fintelmann V, Albrecht U, Schmitz G, Schnitker J. Efficacy and safety of a combination herbal medicinal product containing Tropaeoli majoris herba and Armoraciae rusticanae radix for the prophylactic treatment of patients with respiratory tract diseases:
- Albrecht U, Goos KH, Schneider B. A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients w
- Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Nasturtium
1 brand in our database make a supplement containing Nasturtium.
Supplement products with Nasturtium
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Nasturtium: Common Questions
What is Nasturtium used for, and does it work?
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How are Nasturtium interactions rated?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Nasturtium
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