Herb & supplement monograph

Nasturtium Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Nasturtium

0 medications have a known interaction with Nasturtium, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Nasturtium. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Nasturtium combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Nasturtium: Uses, Safety & Side Effects

The bottom line

Nasturtium is an edible garden plant traditionally used for urinary and respiratory infections, often combined with horseradish in herbal products. Some lab studies suggest it has antimicrobial activity, but high-quality human evidence is limited. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have kidney or stomach problems.

Scientific name
Tropaeolum majus
Family
Tropaeolaceae
Part used
Leaves, flowers, and seeds
Common forms
Fresh leaves and flowers (food/salad), dried herb, tea, capsules, tinctures, and combination herbal products
People commonly use it for
  • Urinary tract infections
  • Respiratory infections and congestion
  • Antimicrobial support
  • Wound and skin care (topical)
  • Mild cold and cough symptoms

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally considered safe as a food, but concentrated extracts have limited safety data.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Nasturtium (Tropaeolum majus) is a flowering plant native to South America that is now grown in gardens around the world. It is popular as an ornamental plant, and its colorful flowers and peppery-tasting leaves are also used in cooking and salads.

Beyond food, nasturtium has a long history in traditional and folk medicine. People have used its leaves, flowers, and seeds for urinary and respiratory complaints and as a natural antimicrobial. In some countries, nasturtium is combined with horseradish in herbal products marketed for infections of the urinary and respiratory tracts.

How it works

Nasturtium is rich in compounds called glucosinolates, which break down into substances known as isothiocyanates (including benzyl isothiocyanate). These are the same family of compounds that give the plant its sharp, peppery taste.

In laboratory studies, these isothiocyanates appear to have antimicrobial activity against some bacteria and fungi. The plant also contains vitamin C and antioxidant compounds. It is important to know that most of this research is based on lab or animal studies, so it does not necessarily mean the same effects happen in the human body.

Effectiveness

Does Nasturtium work?

Evidence overview · 2 uses evaluated
2 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Nasturtium, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Respiratory tract infections
Rating & evidence shown verbatim from Natural Medicines

Preliminary clinical research in patients with a history of recurrent respiratory tract infections (RTIs) shows that taking a specific combination product (Angocin Anti-Infekt N, Repha GmbH) containing a total of 320-400 mg horseradish root and 800-1000 mg nasturtium daily for 12 weeks modestly decreases the rate of new RTIs when compared with placebo. However, there were no differences between groups in time to infection, intensity or duration of infection, or rates of specific infections, including acute rhinopharyngitis, sinusitis, laryngitis, or tracheitis. Also, it is not clear if this effect is due to nasturtium, horseradish, or the combination.

Sources Ref 96309
Insufficient Reliable Evidence To Rate Urinary tract infections (UTIs)
Rating & evidence shown verbatim from Natural Medicines

A small clinical study in patients with recurrent UTIs shows that taking a specific product (Angocin Anti-Infekt N, Repha GmbH) containing a total of 320 mg horseradish root and 800 mg nasturtium daily for 90 days modestly reduces the recurrence of UTIs when compared with placebo at 3 months after treatment completion, but not at the time of treatment completion. However, this analysis excluded patients that were not cured from their initial active UTI. Additionally, the small size, short duration, and high dropout rate in this study limits the validity of these findings. Furthermore, it is not clear if this effect is due to nasturtium, horseradish, or the combination.

Sources Ref 96310

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

When eaten in normal food amounts, nasturtium leaves and flowers are generally considered safe for most people. The safety of concentrated extracts, capsules, and long-term medicinal use is less well studied.

People with stomach or intestinal ulcers or kidney problems should be cautious, since the plant's pungent compounds may irritate these areas. Children and people with sensitive stomachs should also use caution.

For pregnancy, there is not enough reliable safety information, so medicinal amounts should be avoided. For breastfeeding, safety is also unclear, so it is best to be cautious or avoid concentrated products. Always check with your pharmacist or doctor before starting nasturtium, especially if you take other medicines or have a health condition.

Side effects

Nasturtium is usually well tolerated as a food. When taken in larger or concentrated amounts, possible side effects include stomach upset, heartburn, or irritation of the digestive tract because of its spicy isothiocyanate compounds.

Some people may have an allergic reaction or skin irritation, especially when it is applied to the skin. Stop using it and seek medical care if you notice swelling, trouble breathing, or a severe rash.

Nasturtium: Reported Adverse Effects

Documented safety reports on Nasturtium from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, large amounts of nasturtium or benzyl mustard oil, a constituent of nasturtium, can cause gastrointestinal tract irritation. Large amounts of nasturtium can cause albuminuria due to glomerular and tubular damage.

Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation. Benzyl mustard oil is a contact allergen if applied to the skin; case reports of contact dermatitis have been attributed to the nasturtium plant.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30.
Reports by condition
Albuminuria Renal

Orally, large amounts of nasturtium can cause albuminuria due to glomerular and tubular damage.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
Dermatitis Dermatologic

Topically, contact with the nasturtium plant and its benzyl mustard oil constituent can cause skin and mucosal irritation. Benzyl mustard oil is a contact allergen if applied to the skin. There are multiple case reports of contact dermatitis attributed to nasturtium.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no well-established standardized dose for nasturtium. Amounts vary widely depending on whether you use fresh leaves, dried herb, tea, capsules, or a combination product.

The best approach is to follow the directions on the product label and not exceed the recommended amount. Because product strengths differ and reliable dosing research is lacking, check with your pharmacist or doctor before using nasturtium as a supplement.

Pregnancy & Breastfeeding

Nasturtium & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.

Nasturtium & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using nasturtium by itself or in combination with other herbs.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 5 references that drive our Nasturtium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Fintelmann V, Albrecht U, Schmitz G, Schnitker J. Efficacy and safety of a combination herbal medicinal product containing Tropaeoli majoris herba and Armoraciae rusticanae radix for the prophylactic treatment of patients with respiratory tract diseases:
  4. Albrecht U, Goos KH, Schneider B. A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients w
  5. Perez-Crespo M, Silvestre JF, Mataix J, Ballester I, Toledo F, Betlloch I. Contact dermatitis due to nasturtium. Contact Dermatitis. 2009;60(4):229-30. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Nasturtium

1 brand in our database make a supplement containing Nasturtium.

Pharmacist Counseling Corner

Nasturtium: Common Questions

What is Nasturtium used for, and does it work?
People use Nasturtium for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Nasturtium interact with prescription medications?
We do not currently list any known drug interactions for Nasturtium. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Nasturtium interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Nasturtium with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Nasturtium interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Nasturtium used for?
It is traditionally used for urinary tract infections, respiratory infections like colds and coughs, and as a natural antimicrobial. Evidence for these uses is limited, so it should not replace proven treatments.
Can you eat Nasturtium?
Yes. The leaves and flowers are edible and have a peppery flavor, and they are commonly added to salads. Eating it in food amounts is generally considered safe for most people.
Is Nasturtium safe during pregnancy or breastfeeding?
There is not enough reliable information to consider medicinal amounts safe during pregnancy or breastfeeding. It is best to avoid concentrated supplements and check with your doctor first.
Does Nasturtium really fight infections?
Lab studies suggest its compounds can slow the growth of some bacteria and fungi, but strong human evidence is lacking. Do not rely on it to treat a serious infection instead of seeing a healthcare provider.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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