Herb & supplement monograph

Ox-eye Daisy Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Ox-eye Daisy

0 medications have a known interaction with Ox-eye Daisy, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Ox-eye Daisy. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Ox-eye Daisy combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Ox-eye Daisy: Uses, Safety & Side Effects

The bottom line

Ox-eye daisy is a traditional European folk remedy used for coughs, digestion, and minor skin problems, but there is very little modern scientific research to confirm any of these uses. Because it belongs to the same family as ragweed, it may trigger allergic reactions, and its safety has not been well studied. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Scientific name
Leucanthemum vulgare
Family
Asteraceae
Part used
Flowers, leaves, and aerial parts (whole flowering plant)
Common forms
Tea, dried herb, tincture, topical preparations (lotions, washes)
People commonly use it for
  • Cough and bronchial complaints
  • Digestive upset
  • Wound healing and skin conditions
  • Mild spasms or cramps
  • As a traditional tonic

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Limited safety data exist, and it may cause allergic reactions in sensitive people.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Ox-eye daisy (Leucanthemum vulgare, once called Chrysanthemum leucanthemum) is a perennial wildflower with the classic white petals and a yellow center. It is native to Europe and parts of Asia and now grows widely across North America and other regions, often in fields, meadows, and along roadsides.

The plant belongs to the daisy or aster family (Asteraceae), which also includes chamomile, ragweed, and chrysanthemums. In traditional European herbal medicine, the flowers and leaves have been brewed into teas or made into tinctures and skin washes. Today it is sometimes sold as a dried herb or tea, but it is far less common than other herbs in this family.

Uses & effectiveness

Ox-eye daisy has a long history in folk medicine, where it was used much like its relative chamomile. People traditionally used it for coughs, bronchial irritation, and asthma-like complaints, as well as for digestive upset, mild cramps or spasms, and as a wash for wounds, bruises, and skin irritation.

It is important to be honest here: there is very little modern scientific research on ox-eye daisy. Most of what is known comes from historical herbal texts and laboratory studies of plant compounds, not from well-designed human trials. Because of this, there is no strong evidence that ox-eye daisy effectively treats any health condition. Any benefits remain unproven.

How it works

Like many plants in the daisy family, ox-eye daisy contains compounds such as flavonoids, tannins, and small amounts of volatile (essential) oils. These substances have antioxidant and mild astringent properties in laboratory tests, which is one reason the plant was traditionally used as a skin wash and cough remedy.

It is important to understand that these proposed actions are mostly based on laboratory studies of plant chemistry rather than studies in people. We do not have good human research showing how ox-eye daisy behaves in the body or whether its compounds are absorbed in meaningful amounts. So any explanation of "how it works" should be viewed as theoretical.

Safety & precautions

Ox-eye daisy has been consumed in small amounts as part of folk medicine, but its safety has not been carefully studied in modern research. The biggest known concern is allergy. Because it is in the Asteraceae (daisy) family, people who are allergic to ragweed, chrysanthemums, marigolds, chamomile, or other related plants may also react to ox-eye daisy.

People with asthma or known plant allergies should be especially cautious. Children and people with chronic health conditions should not use it without professional advice.

Pregnancy and breastfeeding: There is not enough reliable information to consider ox-eye daisy safe during pregnancy or while breastfeeding, so it is best to avoid it during these times. Always check with a pharmacist or doctor before using any herbal product.

Side effects

Reported side effects are not well documented because the plant has not been studied much. The most likely problems are allergic reactions, which can range from skin rash and itching to, rarely, more serious reactions in highly sensitive people. Handling the plant can cause contact dermatitis (skin irritation) in some individuals.

As with many herbal teas and tinctures, taking large amounts could cause stomach upset or nausea. If you notice swelling, trouble breathing, hives, or any severe reaction, stop using it and seek medical care right away.

Dosing

There is no established or standardized dose for ox-eye daisy. Traditional use involved brewing the dried flowers or leaves as a tea, but reliable, research-based dosing guidelines do not exist.

If you choose to use a commercial product, follow the directions on the label and do not exceed them. Because quality and strength vary between products, and because safety data are limited, it is wise to talk with a pharmacist or doctor before starting ox-eye daisy.

Pregnancy & Breastfeeding

Ox-eye Daisy & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Ox-eye Daisy & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 sources that drive our Ox-eye Daisy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Using Dietary Supplements Wisely — NIH NCCIH Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Pharmacist Counseling Corner

Ox-eye Daisy: Common Questions

Does Ox-eye Daisy interact with prescription medications?
We do not currently list any known drug interactions for Ox-eye Daisy. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Ox-eye Daisy interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Ox-eye Daisy with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Ox-eye Daisy interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Ox-eye Daisy used for?
Traditionally it has been used for coughs, digestive complaints, mild cramps, and as a wash for minor skin problems. However, there is little modern scientific evidence that it works for any of these uses.
Is Ox-eye Daisy safe to take?
Its safety has not been well studied. The main concern is allergic reactions, especially in people allergic to ragweed, chamomile, or other daisy-family plants. Check with a pharmacist or doctor before using it.
Can I use Ox-eye Daisy if I'm pregnant or breastfeeding?
No reliable safety information is available, so it is best to avoid Ox-eye Daisy during pregnancy and breastfeeding.
Is Ox-eye Daisy the same as chamomile?
No. They are different plants, though both belong to the daisy (Asteraceae) family. Because they are related, someone allergic to one may react to the other.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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