Herb & supplement monograph

Quince Drug Interactions, Uses, Effectiveness, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Quince

0 medications have a known interaction with Quince, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Quince. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Quince combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Quince: Uses, Safety & Side Effects

The bottom line

Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.

Scientific name
Cydonia oblonga
Family
Rosaceae
Part used
Fruit, seeds, and leaves
Common forms
Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts
People commonly use it for
  • Digestive upset and diarrhea
  • Acid reflux and heartburn
  • Sore throat and cough
  • Skin soothing and wound care
  • Nausea

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Quince as a food is generally well tolerated, but concentrated supplements are not well studied.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Quince (Cydonia oblonga) is a fruit-bearing tree in the rose family, related to apples and pears. The fruit is yellow, fragrant, and very tart, so it is usually cooked into jams, jellies, syrups, and desserts rather than eaten raw. The tree grows in parts of Asia, the Middle East, the Mediterranean region, and other temperate areas.

People have used quince fruit, seeds, and leaves in traditional medicine for hundreds of years. It is most often linked with soothing the stomach and digestive tract, calming a sore throat, and softening or protecting the skin. Today you may find quince as fresh fruit, syrups, teas, and supplement forms such as extracts or capsules.

How it works

Quince contains plant compounds such as antioxidants (including polyphenols and flavonoids), vitamin C, and fiber like pectin. The seeds release a slippery, gel-like mucilage when soaked in water. This mucilage is thought to coat and soothe the throat and digestive lining, which may help explain its traditional use for reflux and irritation.

Laboratory studies suggest quince extracts may have antioxidant and antimicrobial activity, and some animal research points to possible anti-inflammatory effects. Keep in mind that these findings are early and based mostly on test-tube or animal studies, so they may not translate to the same benefits in people.

Effectiveness

Does Quince work?

Evidence overview · 6 uses evaluated
1 Possibly effective 5 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.
Possibly Effective Gastroesophageal reflux disease (GERD)
Rating & evidence shown verbatim from Natural Medicines

Clinical research suggests that oral quince fruit extract may be beneficial for reducing symptoms of GERD in children 7 months and older. Its benefits in adults are unclear.

Also studied for 5 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Allergic rhinitis (hay fever)
Rating & evidence shown verbatim from Natural Medicines

Intranasal quince has only been evaluated in combination with other ingredients; its effects when used alone are unclear.

Insufficient Reliable Evidence To Rate Asthma
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral quince for asthma, there is insufficient reliable information about the clinical effects of quince for this purpose.

Insufficient Reliable Evidence To Rate Peptic ulcers
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral quince for peptic ulcers, there is insufficient reliable information about the clinical effects of quince for this purpose.

Insufficient Reliable Evidence To Rate Pregnancy-induced nausea and vomiting
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral quince syrup is beneficial for morning sickness.

Insufficient Reliable Evidence To Rate Wound healing
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using topical quince for wound healing, there is insufficient reliable information about the clinical effects of quince for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Quince eaten as a cooked food is generally considered safe for most people. Concentrated supplements, seed products, and extracts have not been studied as carefully, so their long-term safety is unknown.

One important caution: quince seeds, like the seeds of apples and other related fruits, contain compounds that can release small amounts of cyanide if crushed and eaten in large quantities. Do not chew or grind raw seeds. People with allergies to fruits in the rose family (such as apples, pears, peaches) should be cautious.

For pregnancy and breastfeeding, quince as a normal food is likely fine, but there is not enough reliable information on concentrated quince extracts or seed products. To be safe, avoid supplement-strength quince during these times unless your doctor approves. Always check with a pharmacist or doctor before starting any new supplement.

Side effects

When eaten as food, quince rarely causes problems. Possible side effects, especially with large amounts or concentrated products, may include mild stomach upset, constipation (the fruit is high in tannins and fiber), or an allergic reaction in people sensitive to related fruits.

Serious effects are uncommon, but eating crushed quince seeds in large amounts could in theory cause cyanide-related toxicity. Stop using quince and seek medical care if you have signs of an allergic reaction such as rash, swelling, or trouble breathing.

Dosing

There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.

If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds. Because doses are not well established, it is best to check with a pharmacist or doctor before using quince supplements, especially if you take medications or have a health condition.

Pregnancy & Breastfeeding

Quince & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Quince & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Quince

25 products in our database contain Quince. Open any to see its full ingredient list and every drug interaction we check.

Advanced Lung & Bronchial Support by Dr. Sinatra Capsule 60 Capsule(s) View ingredients & interactions Bio Cleanse by Plexus Capsule 180 Capsule(s) View ingredients & interactions Essential Detox by AN American Nutriceuticals Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Essential Detox by AN American Nutriceuticals Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Frame Builder by Ron Teeguarden's Dragon Herbs Capsule 100 Vegetarian Capsule(s) View ingredients & interactions Frame Builder by Ron Teeguarden's Dragon Herbs Capsule 100 Vegetarian Capsule(s) View ingredients & interactions Hair & Nails by Ron Teeguarden's Dragon Herbs Capsule 100 Vegetarian Capsule(s) View ingredients & interactions Hair & Nails by Ron Teeguarden's Dragon Herbs Capsule 100 Vegetarian Capsule(s) View ingredients & interactions Hydroxycut Black Onyx by MuscleTech Capsule 120 Capsule(s) View ingredients & interactions ProBio 5 by Plexus Capsule 60 Capsule(s) View ingredients & interactions Quercetin Plus by True Botanica Capsule 60 Capsule(s) View ingredients & interactions Quince by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Quince by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Quince 450 mg by TerraVita Premium Collection Capsule 100 Capsule(s) View ingredients & interactions Quince Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Quince Powder by TerraVita Premium Collection Powder 1 Ounce(s) View ingredients & interactions SC-W by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions SC-W by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Ultimate Lung & Bronchial Support by Dr. Sinatra Softgel Capsule 60 Softgel(s) View ingredients & interactions Women's Once Daily High Potency Multivitamin/Multimineral by Trader Joe's Tablet Or Pill 60 Tablet(s) View ingredients & interactions Advanced Lung & Bronchial Support by Dr. Sinatra Capsule 60 Capsule(s) Off market View ingredients & interactions Advanced Lung & Bronchial Support by Dr. Sinatra Capsule 60 Capsule(s) Off market View ingredients & interactions Essential Detox by AN American Nutriceuticals Tablet Or Pill 60 Tablet(s) Off market View ingredients & interactions naNOX9 Next Gen by MuscleTech Performance Series Other (e.g. Tea Bag) 120 Rapid Cap(s) Off market View ingredients & interactions
Pharmacist Counseling Corner

Quince: Common Questions

What is Quince used for, and does it work?
People use Quince for many reasons, but the evidence varies by use. According to the Natural Medicines database, there is at least some clinical evidence supporting Quince for Gastroesophageal reflux disease (GERD). For most other uses it has been studied for, the evidence is currently insufficient to rate. See the graded list on this page, and always confirm with your pharmacist or doctor.
Does Quince interact with prescription medications?
We do not currently list any known drug interactions for Quince. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Quince interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Quince with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Quince interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Quince used for?
Quince is traditionally used for digestive upset, diarrhea, acid reflux, sore throat, cough, and soothing the skin. Scientific evidence for these uses is limited, so it should not replace proven treatments.
Can I eat Quince raw?
Quince is very tart and hard when raw, so it is almost always cooked into jams, syrups, or desserts. Cooking makes it sweeter and easier to digest.
Is Quince safe during pregnancy?
Quince eaten as a cooked food is likely fine, but concentrated extracts and seed products have not been well studied in pregnancy. To be safe, avoid supplement-strength Quince unless your doctor approves.
Are Quince seeds dangerous?
Whole, intact seeds passed through the body are usually not a concern, but crushed or chewed seeds can release small amounts of cyanide, so do not grind or eat them in large quantities.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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