Quince Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Quince interacts with medications. The heart of this page is the interaction list — every drug Quince is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Quince is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Quince against your medication
Add one medicationDrugs that interact with Quince
0 medications have a known interaction with Quince, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Quince. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Quince combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Quince: Uses, Safety & Side Effects
Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.
- Scientific name
- Cydonia oblonga
- Family
- Rosaceae
- Part used
- Fruit, seeds, and leaves
- Common forms
- Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts
- Digestive upset and diarrhea
- Acid reflux and heartburn
- Sore throat and cough
- Skin soothing and wound care
- Nausea
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Quince as a food is generally well tolerated, but concentrated supplements are not well studied.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Quince (Cydonia oblonga) is a fruit-bearing tree in the rose family, related to apples and pears. The fruit is yellow, fragrant, and very tart, so it is usually cooked into jams, jellies, syrups, and desserts rather than eaten raw. The tree grows in parts of Asia, the Middle East, the Mediterranean region, and other temperate areas.
People have used quince fruit, seeds, and leaves in traditional medicine for hundreds of years. It is most often linked with soothing the stomach and digestive tract, calming a sore throat, and softening or protecting the skin. Today you may find quince as fresh fruit, syrups, teas, and supplement forms such as extracts or capsules.
How it works
Quince contains plant compounds such as antioxidants (including polyphenols and flavonoids), vitamin C, and fiber like pectin. The seeds release a slippery, gel-like mucilage when soaked in water. This mucilage is thought to coat and soothe the throat and digestive lining, which may help explain its traditional use for reflux and irritation.
Laboratory studies suggest quince extracts may have antioxidant and antimicrobial activity, and some animal research points to possible anti-inflammatory effects. Keep in mind that these findings are early and based mostly on test-tube or animal studies, so they may not translate to the same benefits in people.
Does Quince work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
Possibly Effective Gastroesophageal reflux disease (GERD)
Clinical research suggests that oral quince fruit extract may be beneficial for reducing symptoms of GERD in children 7 months and older. Its benefits in adults are unclear.
Also studied for 5 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Allergic rhinitis (hay fever)
Intranasal quince has only been evaluated in combination with other ingredients; its effects when used alone are unclear.
Insufficient Reliable Evidence To Rate Asthma
Although there has been interest in using oral quince for asthma, there is insufficient reliable information about the clinical effects of quince for this purpose.
Insufficient Reliable Evidence To Rate Peptic ulcers
Although there has been interest in using oral quince for peptic ulcers, there is insufficient reliable information about the clinical effects of quince for this purpose.
Insufficient Reliable Evidence To Rate Pregnancy-induced nausea and vomiting
It is unclear if oral quince syrup is beneficial for morning sickness.
Insufficient Reliable Evidence To Rate Wound healing
Although there has been interest in using topical quince for wound healing, there is insufficient reliable information about the clinical effects of quince for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Quince eaten as a cooked food is generally considered safe for most people. Concentrated supplements, seed products, and extracts have not been studied as carefully, so their long-term safety is unknown.
One important caution: quince seeds, like the seeds of apples and other related fruits, contain compounds that can release small amounts of cyanide if crushed and eaten in large quantities. Do not chew or grind raw seeds. People with allergies to fruits in the rose family (such as apples, pears, peaches) should be cautious.
For pregnancy and breastfeeding, quince as a normal food is likely fine, but there is not enough reliable information on concentrated quince extracts or seed products. To be safe, avoid supplement-strength quince during these times unless your doctor approves. Always check with a pharmacist or doctor before starting any new supplement.
Side effects
When eaten as food, quince rarely causes problems. Possible side effects, especially with large amounts or concentrated products, may include mild stomach upset, constipation (the fruit is high in tannins and fiber), or an allergic reaction in people sensitive to related fruits.
Serious effects are uncommon, but eating crushed quince seeds in large amounts could in theory cause cyanide-related toxicity. Stop using quince and seek medical care if you have signs of an allergic reaction such as rash, swelling, or trouble breathing.
Dosing
There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.
If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds. Because doses are not well established, it is best to check with a pharmacist or doctor before using quince supplements, especially if you take medications or have a health condition.
Quince & Pregnancy
Quince & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
Keep readingThis information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Quince
10 brands in our database make a supplement containing Quince.
Supplement products with Quince
25 products in our database contain Quince. Open any to see its full ingredient list and every drug interaction we check.
Quince: Common Questions
What is Quince used for, and does it work?
Does Quince interact with prescription medications?
How are Quince interactions rated?
Is it safe to take Quince with my medications?
Where does this Quince interaction information come from?
What is Quince used for?
Can I eat Quince raw?
Is Quince safe during pregnancy?
Are Quince seeds dangerous?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Quince
A rotating sample of real supplements in our database that list Quince — open any to see its full ingredients and every drug interaction we check.
- Frame Builder by Ron Teeguarden's Dragon Herbs
- Quince by Pure Herbs
- Quince 450 mg by TerraVita Premium Collection
- Women's Once Daily High Potency Multivitamin/Multimineral by Trader Joe's
- Bio Cleanse by Plexus
- SC-W by Pure Herbs
- Quercetin Plus by True Botanica
- Essential Detox by AN American Nutriceuticals
- Quince Powder by TerraVita Premium Collection
- ProBio 5 by Plexus
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