Xanthoparmelia Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Xanthoparmelia interacts with medications. The heart of this page is the interaction list — every drug Xanthoparmelia is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Xanthoparmelia is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Xanthoparmelia against your medication
Add one medicationDrugs that interact with Xanthoparmelia
0 medications have a known interaction with Xanthoparmelia, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Xanthoparmelia. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Xanthoparmelia combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Xanthoparmelia: Uses, Safety & Side Effects
Xanthoparmelia is a type of lichen marketed mainly in supplements promoted for erectile dysfunction and sexual performance, but there is very little reliable human research to support these uses. Some 'male enhancement' products containing it have been found spiked with hidden prescription drugs, which is a real safety concern. Talk with your pharmacist or doctor before using it.
- Scientific name
- Xanthoparmelia scabrosa
- Family
- Parmeliaceae
- Part used
- Whole lichen (thallus)
- Common forms
- Capsules, tablets, powders (often in 'male enhancement' supplement blends)
- Erectile dysfunction
- Sexual performance
- Libido support
- General 'male enhancement'
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
There is not enough reliable safety data, and related products have been adulterated with hidden drugs.
When used orally. Scabrosin esters contained in xanthoparmelia are considered toxic.
Read the full pregnancy detailWhen used orally. Scabrosin esters contained in xanthoparmelia are considered toxic.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Xanthoparmelia is a genus of lichen, which is an organism made of a fungus and an alga (or cyanobacterium) living together. Lichens like Xanthoparmelia grow on rocks and other surfaces in many parts of the world. The species most often mentioned in supplements is Xanthoparmelia scabrosa.
In the supplement world, Xanthoparmelia is best known as an ingredient in products marketed for erectile dysfunction and 'male enhancement.' It is usually sold as a capsule, tablet, or powder, often combined with other herbs in a blend. Despite its popularity in these products, it is not a traditional herbal remedy with a long, well-documented history of use.
How it works
There is no well-established, proven mechanism for how Xanthoparmelia might affect sexual function. Lichens contain a variety of natural compounds, sometimes called lichen acids, which have been studied in the laboratory for possible antimicrobial and antioxidant activity.
However, these laboratory or test-tube findings do not prove the lichen works for erectile dysfunction or any other condition in people. Any claims about boosting blood flow or sexual performance are largely unproven, and in some cases reported 'effects' may actually be due to hidden pharmaceutical ingredients found in adulterated products.
Does Xanthoparmelia work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Xanthoparmelia, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 4 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Cancer
Although there has been interest in using oral xanthoparmelia for cancer, there is insufficient reliable information about the clinical effects of xanthoparmelia for this purpose.
Insufficient Reliable Evidence To Rate Erectile dysfunction (ED)
Although there has been interest in using oral xanthoparmelia for ED, there is insufficient reliable information about the clinical effects of xanthoparmelia for this purpose.
Insufficient Reliable Evidence To Rate Sexual desire
Although there has been interest in using oral xanthoparmelia for increasing sexual desire, there is insufficient reliable information about the clinical effects of xanthoparmelia for this purpose.
Insufficient Reliable Evidence To Rate Sexual dysfunction
Although there has been interest in using oral xanthoparmelia for sexual dysfunction, there is insufficient reliable information about the clinical effects of xanthoparmelia for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
The overall safety of Xanthoparmelia in supplements is not well understood. There is little reliable human research on how much is safe or what long-term use might do.
A major concern is product quality. Because Xanthoparmelia appears in 'male enhancement' supplements, and these products are a known target for adulteration with hidden prescription drugs, you may not actually know what you are taking. Hidden drugs can be dangerous, especially for people with heart disease, high or low blood pressure, or those taking nitrate medicines.
People with existing health conditions, older adults, and anyone taking regular medications should be especially cautious and check with a healthcare professional first. Pregnant and breastfeeding people should avoid Xanthoparmelia, since there is not enough information to consider it safe.
Side effects
Because Xanthoparmelia has not been carefully studied in people, its side effect profile is largely unknown. As with many supplements, possible mild effects could include stomach upset or headache.
More serious risks are often linked to contaminated or adulterated products rather than the lichen itself. Hidden erectile dysfunction drugs in these supplements can cause a dangerous drop in blood pressure, dizziness, flushing, chest pain, vision changes, or prolonged erection. Stop use and seek medical care if you notice serious or unexpected symptoms.
Dosing
There is no established or standardized dose of Xanthoparmelia. Amounts vary widely between products, and many are proprietary blends that do not clearly list how much lichen they contain.
If you choose to use a product containing Xanthoparmelia, follow the label directions and do not exceed them. Because of quality and adulteration concerns, it is best to talk with your pharmacist or doctor first and choose products that have been independently tested for purity.
Xanthoparmelia & Pregnancy
Xanthoparmelia & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Xanthoparmelia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Moerman KL, Chai CL, Waring P. Evidence that the lichen-derived scabrosin esters target mitochondrial ATP synthase in P388D1 cells. Toxicol Appl Pharmacol 2003;190:232-40. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Xanthoparmelia
28 brands in our database make a supplement containing Xanthoparmelia.
Supplement products with Xanthoparmelia
75 products in our database contain Xanthoparmelia. Open any to see its full ingredient list and every drug interaction we check.
Xanthoparmelia: Common Questions
What is Xanthoparmelia used for, and does it work?
Does Xanthoparmelia interact with prescription medications?
How are Xanthoparmelia interactions rated?
Is it safe to take Xanthoparmelia with my medications?
Where does this Xanthoparmelia interaction information come from?
What is Xanthoparmelia used for?
Does Xanthoparmelia actually work for erectile dysfunction?
Is Xanthoparmelia safe to take?
Can I take it while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Xanthoparmelia
A rotating sample of real supplements in our database that list Xanthoparmelia — open any to see its full ingredients and every drug interaction we check.
- Bio-Hard by BioXgenic
- Xanthoparmelia 35% Extract Powder by TerraVita Premium Collection
- T Support by ViMulti
- Black Snake Gold by Vigor Labs
- Xanthoparmelia 10:1 Extract Powder by TerraVita Premium Collection
- Xanthoparmelia 450 mg 35% Extract by TerraVita Premium Collection
- Vialafil XR by NewtonEverett
- Enpulse by Rivalus
- Zyrexin 525 mg by Superbalife International
- Testosterole Maximum Libido Complex by Maximum International
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