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Dietary supplement

100% Pure Activated Charcoal 260 mg Ingredients & Drug Interactions

by Source Naturals

100% Pure Activated Charcoal 260 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 100% Pure Activated Charcoal 260 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

100% Pure Activated Charcoal 260 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Charcoal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against 100% Pure Activated Charcoal 260 mg by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure Activated Charcoal 260 mg by Source Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of 100% Pure Activated Charcoal 260 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 260 mg of activated charcoal per capsule. The capsules themselves are made from gelatin, magnesium stearate, and silica — standard inactive ingredients that help hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Activated Charcoal's overall clinical evidence instead.

Moderate

Some clinical evidence supports Activated Charcoal for:

Why this rating?
  • The label markets general wellness (“digestive aid”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Poisoning — rated "Possibly Effective" (Natural Medicines).

Activated charcoal is possibly effective for poisoning. For other uses — high blood phosphate (hyperphosphatemia), wound healing, indigestion (dyspepsia), hangover, and high cholesterol — the evidence we hold isn't strong enough to rate whether it works.

If you're considering this supplement for a specific reason, talk to your pharmacist about what the research actually shows for your situation.

The evidence, ingredient by ingredient Activated Charcoal

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Activated charcoal is generally well tolerated over short periods, but it commonly causes constipation, black stools, bloating, abdominal pain, and gas. These are usually temporary.

Rarely, it can cause a blockage in your digestive tract. Safety data for routine use during pregnancy and breastfeeding is limited; use only under medical guidance if you're pregnant or nursing.

Because of how charcoal works, it may interfere with absorption of other substances — one more reason to check with your pharmacist before starting.

Side effects, ingredient by ingredient Activated Charcoal

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Activated Charcoal.
  • The most serious interaction on file is rated Major.
  • For scale: 2,028 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you use any oral medications — activated charcoal can reduce how well they work (Major severity). Also double-check if you take oral contraceptives (birth control), as charcoal may reduce their effectiveness (Moderate severity).

And avoid taking charcoal and alcohol close together, since alcohol can reduce charcoal's binding ability.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Activated charcoal may be helpful in specific situations, but its strong binding action means it can interfere with many medications and nutrients. If you take any prescription or regular over-the-counter drugs, check them against our medication database before you use this product.

Talk to your pharmacist about whether the timing and dose work for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Pure Activated Charcoal 260 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078006862
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 295621
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Pure Activated Charcoal 260 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
021078006862
IngredientAmount% DV
Charcoal520 mg--

Other ingredients: Gelatin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

Digestive aid

Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Suggested/Recommended/Usage/Directions

Suggested use: 2 capsules, preferably after meals, up to 3 times daily, at first sign of internal imbalance. Take for no more than 3 consecutive days.

Precautions

Do not use if either tamper-evident seal is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant, breastfeeding or may become pregnant, or if you are taking any prescription medication (including oral contraceptives), consult a physician before using this product. My reduce effectiveness of certain medications.

Not for children under 3 years of age.

May temporarily darken the stool.

Charcoal should be taken at least 1 hour before or 2 hours after taking medication.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright Source Naturals, INC.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

100% Pure Activated Charcoal 260 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

100% Pure Activated Charcoal 260 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 100% Pure Activated Charcoal 260 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Charcoal

Interacts with
2,027 drugs
520 mg per serving

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...

Charcoal monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

100% Pure Activated Charcoal 260 mg by Source Naturals Drug Interactions

Want to check YOUR meds against 100% Pure Activated Charcoal 260 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,027Drugs
2,022 Major 5 Moderate

Ingredients driving the most interactions

Charcoal 2,027

Individual Drug Interactions

The ingredients in 100% Pure Activated Charcoal 260 mg interact with 2,027 drugs. Click any drug to see the details.

1 of the 1 ingredient in 100% Pure Activated Charcoal 260 mg interact with drugs. Each result below shows which ingredient is responsible. Charcoal

Each ingredient & the kinds of drugs it affects

For each ingredient in 100% Pure Activated Charcoal 260 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Charcoal3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B
Charcoal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 100% Pure Activated Charcoal 260 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

100% Pure Activated Charcoal 260 mg by Source Naturals: Common Questions

Does 100% Pure Activated Charcoal 260 mg by Source Naturals interact with any medications?
Yes. Based on its ingredients, 100% Pure Activated Charcoal 260 mg has a known interaction with 2,027 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
100% Pure Activated Charcoal 260 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this charcoal interact with my prescription medications?
Yes, it can. Activated charcoal binds to many drugs in your digestive system and may lower how much of them your body absorbs, making them less effective. Use the medication checker on this page to look up each medication you take.
Can I take this if I'm on birth control?
Activated charcoal may reduce how well oral contraceptives work and increase the risk of pregnancy. If you take birth control, check with your pharmacist before starting this product — they may recommend spacing out when you take each one.
What are the most common side effects?
Constipation is the most frequent complaint, along with black stools, bloating, abdominal pain, and gas. These are usually temporary and mild. Rarely, charcoal can cause a blockage in your digestive tract.
Is this safe to use during pregnancy?
The safety data is limited. The available evidence suggests it's possibly safe, but there isn't enough research to be certain. If you're pregnant or nursing, use this only under medical guidance — talk to your doctor or pharmacist first.
Will this work for a hangover?
Activated charcoal is listed as having insufficient evidence for hangover relief in our data. We don't have enough research to say whether it actually helps, so we can't make that claim.
What should I avoid when taking this?
Don't take charcoal at the same time as other medications — space them apart by at least a couple of hours if possible, since charcoal can reduce their absorption. Also avoid alcohol, since it can lower how well the charcoal works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Pure Activated Charcoal 260 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Pure Activated Charcoal 260 mg label
Go deeper

The Full Monographs Behind 100% Pure Activated Charcoal 260 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Activated Charcoal

Interacts with 2,027 drugs

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings and overdoses. For everyday uses like g...

Read the full Activated Charcoal monograph →
Sources

Sources & How We Checked

100% Pure Activated Charcoal 260 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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