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Dietary supplement

100% Pure Glycine 1000 Milligrams Ingredients & Drug Interactions

by NutraBio

100% Pure Glycine 1000 Milligrams label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 100% Pure Glycine 1000 Milligrams against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

100% Pure Glycine 1000 Milligrams is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against 100% Pure Glycine 1000 Milligrams by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure Glycine 1000 Milligrams by NutraBio — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of 100% Pure Glycine 1000 Milligrams by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycine, an amino acid. Each capsule delivers 1,000 milligrams (1 gram).

The capsule itself is made from vegetable material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glycine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

Glycine is rated possibly effective for schizophrenia based on available evidence. For other uses listed on the label — 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, ADHD, benign prostatic hyperplasia (BPH), and cystic fibrosis — there isn't enough reliable evidence yet to say whether it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. A small number of trial participants reported mild sedation, though symptoms went away quickly when they stopped taking it.

Others reported irritability, insomnia, fatigue, memory problems, headache, and sensory changes, though it's unclear if glycine actually caused these. Rare gastrointestinal side effects have included soft stools, nausea, vomiting, and upper stomach discomfort — these also resolved quickly with discontinuation.

Dry mouth has been reported but any link to glycine is unclear. There isn't enough reliable safety data to know how safe glycine is in pregnancy or while breastfeeding, so it's best avoided unless your doctor approves.

Talk with your healthcare provider for personalized advice if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril), check with your pharmacist before starting glycine — it may reduce how well the medication works and worsen schizophrenia symptoms.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine might be worth considering if your doctor thinks you could benefit from it for schizophrenia — the evidence suggests it may help. But if you take clozapine, you'll need to check with your pharmacist or doctor first because glycine may work against it.

For other uses, we don't have solid evidence yet. Because long-term safety data are limited, this is a conversation-with-your-doctor kind of supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 100% Pure Glycine 1000 Milligrams, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908232153
Net contents 240 V-Cap(s)
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 50842
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 100% Pure Glycine 1000 Milligrams by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
120
UPC/BARCODE
649908232153
IngredientAmount% DV
Glycine1000 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

+ These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

23215-001 B20123-001

Formulation

-Allergen Free -Non-GMO -Gluten Free -BSE/TSE Free

No fillers No excipients No additives

Free of Harmful Impurities

Vegetarian

Kosher, Vegetarian, Hypoallergenic, Non GMO, Gluten Free, & BSE/TSE Free

Kosher, Vegetarian, Hypoallergenic, Non GMO, Gluten Free, & BSE/TSE Free

Kosher, Vegetarian, Hypoallergenic, Non GMO, Gluten Free, & BSE/TSE Free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.

Seals/Symbols

Made In USA

TRUE LABEL FULL LABEL DISCLOSURE

OU

Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

General Statements

Manufactured in a GMP & FDA Inspected Facility

Pharmaceutical Grade HPLC Lab Tested for Potency

Free Form Amino Acid

120 servings

Vegetable Capsule

Since 1996

Made in a GMP & FDA Inspected Facility

Formula

Kosher, Vegetarian, Hypoallergenic, Non GMO, Gluten Free, & BSE/TSE Free

Suggested/Recommended/Usage/Directions

2 capsules -1-3x daily -Between meals

Suggested Use: As a dietary supplement, take 1 serving between meals 1-3 times daily or as directed by your physician. If you experience stomach irritation, take with meals.

Brand IP Statement(s)

Amino Therapy

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

100% Pure Glycine 1000 Milligrams by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

100% Pure Glycine 1000 Milligrams label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 100% Pure Glycine 1000 Milligrams by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Glycine

Interacts with
1 drug
1000 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

100% Pure Glycine 1000 Milligrams by NutraBio Drug Interactions

Want to check YOUR meds against 100% Pure Glycine 1000 Milligrams?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Glycine 1

Individual Drug Interactions

The ingredients in 100% Pure Glycine 1000 Milligrams interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in 100% Pure Glycine 1000 Milligrams interact with drugs. Each result below shows which ingredient is responsible. Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in 100% Pure Glycine 1000 Milligrams with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 100% Pure Glycine 1000 Milligrams, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

100% Pure Glycine 1000 Milligrams by NutraBio: Common Questions

Does 100% Pure Glycine 1000 Milligrams by NutraBio interact with any medications?
Yes. Based on its ingredients, 100% Pure Glycine 1000 Milligrams has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
100% Pure Glycine 1000 Milligrams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does glycine actually work for schizophrenia?
The evidence is preliminary. Glycine is rated possibly effective for schizophrenia, but one small clinical trial found that adding it to clozapine actually made symptoms worse. Talk with your doctor about whether it makes sense for your situation.
What side effects might I notice?
Most people tolerate it well. A small number of people reported mild sedation, irritability, insomnia, fatigue, headaches, or stomach upset, but these symptoms went away when they stopped taking it. Long-term safety data are limited, so we don't know what might happen with extended use.
Can I take it while pregnant or breastfeeding?
There isn't enough reliable safety data to know either way. Talk with your doctor or pharmacist before using glycine if you're pregnant, planning pregnancy, or nursing — they can help you decide what's right for you.
Is this just glycine, or are there other ingredients?
It's 100% pure glycine — one gram per capsule. The capsule itself is made from vegetable material.
Does it work for ADHD or prostate problems?
There isn't enough reliable evidence to say whether glycine helps with ADHD or benign prostatic hyperplasia. If either is a concern for you, your doctor can suggest treatments with solid evidence behind them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 100% Pure Glycine 1000 Milligrams is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

100% Pure Glycine 1000 Milligrams label
Go deeper

The Full Monographs Behind 100% Pure Glycine 1000 Milligrams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph →
Sources

Sources & How We Checked

100% Pure Glycine 1000 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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