No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

7-Keto DHEA Metabolite 25 mg Ingredients & Drug Interactions

by Life Extension

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

7-Keto DHEA Metabolite 25 mg is a dietary supplement by Life Extension with 1 active ingredient. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, supporting muscle mass.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 7-Keto DHEA Metabolite 25 mg by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 7-keto DHEA, a metabolite derived from DHEA (a hormone precursor your body makes naturally). Each capsule delivers 25 mg.

The capsule itself is made with gelatin, rice flour, and vegetable stearate—standard binders and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 7-keto-dhea's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss, fat burning, and metabolism support.
  • We looked for evidence on: Obesity, Aging, Muscle strength, Athletic performance, body composition, metabolic rate.
  • The closest evidence on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength, Obesity, Aging.

The evidence for 7-keto DHEA is still developing. Our data shows insufficient evidence to rate it for post-traumatic stress disorder (PTSD), obesity, depression, Raynaud syndrome (a circulation condition where fingers go numb in cold), and aging.

In other words, we don't yet have reliable studies showing whether it works for these uses.

The evidence, ingredient by ingredient 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in small studies, but we don't know much about long-term safety—it hasn't been studied in that way. A few trial participants reported nausea and one reported dizziness.

One case report noted lower blood cell counts (hemoglobin and hematocrit) in a man taking 50 mg daily for a week, though the real-world significance isn't clear. Because this is a hormone-related supplement, safety data advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient 7-keto-dhea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for 7-keto DHEA with any medications. Still, because it's a hormone precursor, mention it to your pharmacist or doctor if you're on hormone-related drugs or anything affecting your blood.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

7-Keto DHEA may appeal to people curious about hormone metabolism and aging, but evidence for its benefits isn't established yet. If you're pregnant or breastfeeding, this isn't the right choice.

Anyone on blood-related or hormone-sensitive medications should check with their pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-Keto DHEA Metabolite 25 mg, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870658108
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231706
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-Keto DHEA Metabolite 25 mg by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
737870658108
IngredientAmount% DV
7-Keto DHEA25 mg--

Other ingredients: Rice Flour, Gelatin, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule in the morning on an empty stomach, or as recommended by a healthcare practitioner.

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Results may vary.

Storage

Store tightly closed in a cool, dry place.

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Formulation

Gluten free

Non GMO LE Certified

Promotes weight management

Seals/Symbols

Non GMO LE Certified

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

7-KETO brand is a registered trademark of InterHealth N.I. U.S. Patent 7,199,116.

See for yourself

7-Keto DHEA Metabolite 25 mg by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-Keto DHEA Metabolite 25 mg by Life Extension

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

7-Keto DHEA

No known
interactions
25 mg per serving

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto DHEA monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-Keto DHEA Metabolite 25 mg by Life Extension Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 7-Keto DHEA Metabolite 25 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 7-Keto DHEA Metabolite 25 mg, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

7-Keto DHEA Metabolite 25 mg by Life Extension: Common Questions

Does 7-Keto DHEA Metabolite 25 mg by Life Extension interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 7-Keto DHEA Metabolite 25 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
7-Keto DHEA Metabolite 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is 7-keto DHEA safe to take long-term?
Short-term use looks generally well tolerated in small trials, but we don't have solid data on long-term safety. If you're thinking of taking it for weeks or months, talk with your pharmacist about what we do and don't know.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against use during pregnancy because there isn't enough information about hormone-related supplements in that setting. For breastfeeding, there's no reliable safety information, so it's best avoided as well.
What's 7-keto DHEA supposed to do?
It's a metabolite of DHEA, a hormone precursor your body makes. The idea is that it may support metabolism and aging, but we don't yet have reliable evidence showing it works for these or other uses.
What side effects did people report in studies?
A few trial participants reported nausea, and one reported dizziness. One case report noted lower blood cell counts in a man taking a higher dose for a short time, though we can't be sure what caused it.
Will this interact with my blood pressure or cholesterol medication?
We have no documented interactions in our data. Still, because 7-keto DHEA is hormone-related, it's worth a quick check-in with your pharmacist before you start, especially if you're on hormone-sensitive drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-Keto DHEA Metabolite 25 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-Keto DHEA Metabolite 25 mg label
Go deeper

The Full Monographs Behind 7-Keto DHEA Metabolite 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

7-Keto DHEA Metabolite 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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