Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Advanced Therapeutics ARA-Larix Rx-Immune Ingredients & Drug Interactions

by Natures Plus

Advanced Therapeutics ARA-Larix Rx-Immune label
See full label image
Tablet Or Pill Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Advanced Therapeutics ARA-Larix Rx-Immune against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Advanced Therapeutics ARA-Larix Rx-Immune is a dietary supplement by Natures Plus with 1 active ingredient. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ARA-Larix. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: ARA-Larix, which is larch arabinogalactan — a type of soluble fiber derived from larch tree bark. It also includes inactive ingredients (fillers and binders) such as di-calcium phosphate, microcrystalline cellulose, vegetable cellulose, stearic acid, magnesium stearate, silica, and pharmaceutical glaze.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Larch Arabinogalactan's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune support and cold prevention.
  • We looked for evidence on: Common cold, flu, respiratory health, immune function.
  • The closest evidence on file: Larch Arabinogalactan is rated "Insufficient Reliable Evidence To Rate" for Common cold (Natural Medicines).

The evidence for larch arabinogalactan is thin. We hold insufficient reliable evidence to say whether it helps with the common cold or high cholesterol (hyperlipidemia).

If lowering cholesterol or cold prevention is your goal, talk with us about options with stronger evidence behind them.

The evidence, ingredient by ingredient Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, larch arabinogalactan is generally well tolerated as a fiber. However, long-term safety data of high quality are limited, so caution is warranted.

Some people experience bloating and flatulence. The safety data available aren't robust enough to recommend it without your doctor's approval — speak with your provider before starting, especially if you have a digestive condition or are pregnant or breastfeeding.

Side effects, ingredient by ingredient Larch Arabinogalactan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Larch Arabinogalactan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take immunosuppressant medications — drugs like cyclosporine, tacrolimus, mycophenolate, or others used after organ transplants or for autoimmune disease — talk with your pharmacist before starting this product. The larch arabinogalactan may reduce how well those medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a single-ingredient supplement of larch arabinogalactan, a soluble fiber with limited evidence for the claims on the label. The main concern is for anyone on immunosuppressant medications after a transplant or for autoimmune disease — the fiber may interfere with how well those drugs work.

If that's you, check with us before adding it. For others, the biggest real risk is digestive bloating.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Therapeutics ARA-Larix Rx-Immune, straight from the product label.

Brand Natures Plus
Barcode (UPC) 097467049833
Net contents 30 Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318987
Product type Fiber And Other Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
097467049833
IngredientAmount% DV
ARA-Larix500 mg--

Other ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Silica, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Gluten free

Vegetarian.

FDA Statement of Identity

Arabinogalactan Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, one tablet with a meal or as recommended by your health care professional.

Storage

Keep tightly closed in a cool, dry place.

Precautions

Keep out of reach of children.

Brand IP Statement(s)

Copyright Natural Organics

General Statements

Peel here

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Advanced Therapeutics ARA-Larix Rx-Immune label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

ARA-Larix

Interacts with
121 drugs
500 mg per serving Form: Larix occidentalis extract

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

ARA-Larix monograph & interactions

Other (inactive) ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Silica, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus Drug Interactions

Want to check YOUR meds against Advanced Therapeutics ARA-Larix Rx-Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

ARA-Larix 121

Individual Drug Interactions

The ingredients in Advanced Therapeutics ARA-Larix Rx-Immune interact with 121 drugs. Click any drug to see the details.

1 of the 1 ingredient in Advanced Therapeutics ARA-Larix Rx-Immune interact with drugs. Each result below shows which ingredient is responsible. ARA-Larix

Each ingredient & the kinds of drugs it affects

For each ingredient in Advanced Therapeutics ARA-Larix Rx-Immune with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ARA-Larix1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
ARA-Larix full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Advanced Therapeutics ARA-Larix Rx-Immune, from the product label.

Natures Plus

See all Natures Plus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus: Common Questions

Does Advanced Therapeutics ARA-Larix Rx-Immune by Natures Plus interact with any medications?
Yes. Based on its ingredients, Advanced Therapeutics ARA-Larix Rx-Immune has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Advanced Therapeutics ARA-Larix Rx-Immune contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually help with colds or high cholesterol?
The evidence we have isn't strong enough to say either way. For both the common cold and high cholesterol, there's insufficient reliable evidence to rate how well larch arabinogalactan works. If those are your concerns, ask us about supplements or treatments with better data behind them.
What are the side effects?
Most people tolerate it well. The main complaint is bloating and flatulence — digestive gas — because it's a fiber. Long-term safety data are limited, so we don't have a full picture of rare or delayed side effects.
Is it safe during pregnancy or breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before taking this while pregnant or nursing — they can give you personalized advice based on your situation.
What exactly is ARA-Larix?
It's larch arabinogalactan, a soluble fiber from larch tree bark. Your body doesn't digest it, so it acts like a prebiotic fiber — food for the good bacteria in your gut.
Can I take this if I'm on an immunosuppressant after a transplant?
Not without checking first. Larch arabinogalactan may interfere with transplant medications like cyclosporine or tacrolimus. Talk to your transplant team or pharmacist before starting — this is a moderate concern worth clearing before you begin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Therapeutics ARA-Larix Rx-Immune is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Therapeutics ARA-Larix Rx-Immune label
Go deeper

The Full Monographs Behind Advanced Therapeutics ARA-Larix Rx-Immune’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph →
Sources

Sources & How We Checked

Advanced Therapeutics ARA-Larix Rx-Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team