Skip to the answer

Betamethasone

Betamethasone is a topical corticosteroid used on the skin to relieve inflammation and itching from corticosteroid-responsive skin conditions, and, in spray form, to treat mild to moderate plaque psoriasis.

Brand names LuxiqBetavetSernivoDel-BetaDiprolene
Drug class Corticosteroid Hormone Receptor Agonists
Rx Forms 3
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 83 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 5, 2026
Other forms & routes:
Topical
Betamethasone at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Betamethasone is a prescription skin steroid that calms red, swollen, itchy skin conditions and, as a spray, mild to moderate plaque psoriasis; it has been around since the early 1960s, is available as a generic, and its augmented versions are among the strongest topical steroids. Short courses are usually well tolerated, and brief burning, stinging or itching where it goes on is the most common complaint. The risk is overuse, which can thin the skin and let steroid soak in to suppress your body's stress-hormone system (the HPA axis), so use the smallest area for the shortest time and stop once the skin is under control.

Clinical pearls

  • Skip the face, groin and underarms unless your prescriber says otherwise, because thin skin there absorbs more steroid.
  • Don't cover treated skin with bandages or plastic wrap unless told to, since covering pushes much more steroid in.
  • Augmented products are usually limited to two weeks with a weekly cap on how much you use, so don't refill indefinitely.
  • Report any vision changes promptly, since skin steroids can raise the risk of cataracts and glaucoma.
How we write & review this content — our editorial policy →
How you get itPrescription only
Comes asTopical cream, ointment or gel, Inhaler, Topical spray
Earliest FDA record1961
Companies listing it with the FDA29
FDA label last updatedApr 22, 2026
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Betamethasone, written from its FDA label.

What Betamethasone is used for

▾

Betamethasone comes in several skin products with somewhat different uses.

  • Betamethasone dipropionate gel, ointment, cream and lotion, including Diprolene Ointment, relieve inflammation and itching from corticosteroid-responsive skin conditions.
  • Betamethasone valerate cream, ointment and lotion are used for the same purpose.
  • Betamethasone valerate foam is for these skin conditions on the scalp.
  • Betamethasone dipropionate spray, including Sernivo, treats mild to moderate plaque psoriasis in adults 18 and older.

How Betamethasone works

▾

Corticosteroids play a role in cell signaling, immune function, inflammation and protein regulation. How the spray works in psoriasis is not precisely known.

Betamethasone dosage

▾

Betamethasone is applied to the skin only. Most dipropionate products are used once or twice daily, while the spray is used twice daily. Betamethasone valerate products may be used more often, and the foam goes on the scalp twice daily.

  • Stop when the skin is under control.
  • Don't use occlusive dressings unless your doctor directs it.
  • Follow your prescriber's directions and the product label.

Dosing details from the FDA-approved label

From the Betamethasone prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Betamethasone dipropionate lotion (augmented), 0.05% (topical)
    • Apply a few drops to the affected skin areas once or twice daily and massage lightly until the lotion disappears
    • Discontinue therapy when control is achieved
    • Limit therapy to no more than 2 consecutive weeks
    • Maximum: No more than 50 mL per week
    • Not for use with occlusive dressings unless directed by a physician; avoid use on the face, groin, or axillae, or if skin atrophy is present
  • Betamethasone dipropionate ointment (augmented), 0.05% / Augmented Betamethasone Dipropionate Ointment / DIPROLENE Ointment (topical)
    • Apply a thin film to the affected skin areas once or twice daily
    • Discontinue therapy when control is achieved
    • Limit therapy to no more than 2 consecutive weeks
    • Maximum: No more than 50 g per week
    • Not for use with occlusive dressings unless directed by a physician; avoid use on the face, groin, or axillae, or if skin atrophy is present
  • Betamethasone dipropionate cream USP (augmented), 0.05% / betamethasone dipropionate cream (augmented) (topical)
    • Apply a thin film to the affected skin areas once or twice daily
    • Discontinue therapy when control is achieved
    • Maximum: No more than 50 g per week
    • Not for use with occlusive dressings unless directed by a physician; avoid use on the face, groin, or axillae, or if skin atrophy is present
  • Betamethasone dipropionate spray (topical)
    • Shake well before use
    • Apply to the affected skin areas twice daily and rub in gently
    • Use for up to 4 weeks
    • Treatment beyond 4 weeks is not recommended
    • Discontinue when control is achieved
    • Do not use if atrophy is present at the treatment site; do not bandage, cover, or wrap the treated area unless directed by a physician; avoid face, scalp, axilla, groin, or other intertriginous areas
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION Apply a few drops of betamethasone dipropionate lotion (augmented), 0.05% to the affected skin areas once or twice daily and massage lightly until the lotion disappears. Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Betamethasone dipropionate lotion (augmented), 0.05% is a super-high-potency topical corticosteroid. Treatment with betamethasone dipropionate lotion (augmented), 0.05% should be limited to 2 consecutive weeks and amounts should not exceed 50 mL per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis [see Warnings and Precautions (5.1) ] . Betamethasone dipropionate lotion (augmented), 0.05% should not be used with occlusive dressings unless directed by a physician. Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site. Avoid contact with eyes. Wash hands after each application. Betamethasone dipropionate lotion (augmented), 0.05% is for topical use only. It is not for oral, ophthalmic, or intravaginal use. • Apply a few drops to the affected skin areas once or twice daily and massage lightly until the lotion disappears.( 2 ) • Discontinue therapy when control is achieved. ( 2 ) • Limit therapy to no more than 2 consecutive weeks. ( 2 ) • Use no more than 50 mL per week. ( 2 ) • Do not use with occlusive dressings unless directed by a physician. ( 2 ) • Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site. ( 2 ) • Not for oral, ophthalmic, or intravaginal use. ( 2 )

Read the full Dosage and Administration section on DailyMed →

Betamethasone side effects

▾

Most side effects occur where the product is applied.

Common side effects

  • Itching at the application site
  • Burning or stinging
  • Pain at the application site
  • Thinning of the skin (atrophy)
  • Dryness or irritation
  • Acne-like breakouts

When to get medical help

  • Call your doctor if you have vision changes. Topical steroids may raise the risk of cataracts and glaucoma.
  • Call your doctor if your skin gets worse or irritated, or you suspect an allergic reaction to the product.
  • Report signs of too much steroid absorption, such as Cushing's syndrome or high blood sugar. These are rare.
  • Tell your doctor if your skin hasn't improved within 2 weeks (for products that carry this instruction).

Less common effects include dryness, irritation, stretch marks, acne-like breakouts and lighter skin patches. Call your doctor about vision changes or signs of an allergic reaction.

Betamethasone warnings and precautions

▾
  • Absorption through the skin can suppress the body's stress-hormone system (HPA axis). This is usually reversible.
  • Risk rises with strong products, large areas, long use, covered skin, liver failure and young age.
  • Topical steroids may increase the risk of cataracts and glaucoma. Keep products out of your eyes.
  • Rarely, Cushing's syndrome and high blood sugar can occur after prolonged use of very large amounts.
  • Stop use if irritation develops, and tell your doctor.

Before taking Betamethasone

▾
  • Don't use it if you're allergic to betamethasone, other corticosteroids, or any ingredient in the product.
  • Check age limits. Many augmented products are for ages 13 and older, and the spray is for adults 18 and older.
  • Tell your doctor if you are pregnant or breastfeeding. Use the smallest area for the shortest time.
  • Avoid the face, groin and underarms unless directed, and avoid skin with atrophy.
  • Tell your doctor if you have liver problems.

What Betamethasone does in the body

▾

In healthy volunteers, betamethasone dipropionate spray tested as mid-range in strength compared with other topical steroids. In a study of adults with extensive psoriasis, some people showed HPA axis suppression after 15 days of twice-daily use. Follow-up tests in those checked were normal.

How your body processes Betamethasone

▾

Topical steroids are absorbed through normal skin. Absorption depends on the product vehicle, the condition of the skin barrier and the use of occlusive dressings. Inflamed or diseased skin absorbs more. In the spray study, most people had no measurable drug in their blood.

How to store Betamethasone

▾

Store at 20° to 25°C (68° to 77°F) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

Betamethasone: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Betamethasone — the kind of thing our pharmacy team would talk through with you at the counter.

What is betamethasone used for?

▾
It calms inflammation and itching from steroid-responsive skin conditions. The spray is specifically for mild to moderate plaque psoriasis in adults. The valerate foam is for the scalp.

How do I apply it?

▾
Use a thin film or a few drops, as your product directs, once or twice a day. The spray is shaken first and used twice daily. Wash your hands afterward and keep it out of your eyes. Follow your prescription label.

How long can I use it?

▾
Not for long. Several products limit use to about 2 weeks and the spray to 4 weeks. Stop when your skin is under control, and call your doctor if you see no improvement within 2 weeks.

What side effects should I expect?

▾
Mild burning, stinging, itching or dryness where you apply it is the most common. Skin thinning can happen with ongoing use. Call me or your doctor if you notice vision changes or your skin gets worse.

Can I put it on my face or cover it with a bandage?

▾
Generally no. Avoid the face, groin and underarms, and don't bandage or wrap the area unless your doctor says to. Covering the skin increases absorption.

Is it safe in pregnancy or for children?

▾
Use it carefully. If you're pregnant or breastfeeding, use the smallest area for the shortest time. Children absorb more through the skin, so many products are for ages 13 and older, and the spray is for adults.

Is Betamethasone available over the counter?

▾
No. Betamethasone is a prescription medicine: every Betamethasone product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Betamethasone first available?

▾
The earliest FDA record we hold for Betamethasone is from 1961: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Betamethasone was first used.

Who makes Betamethasone?

▾
29 companies currently list Betamethasone products in the FDA's NDC Directory, including A-S Medication Solutions, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, Bryant Ranch Prepack. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Betamethasone on HelloPharmacist

🌿Drug & Supplement CheckerBetamethasone vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Betamethasone NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Betamethasone Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Betamethasone forms and strengths (how it comes)

Betamethasone is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Betamethasone inactive ingredients by manufacturer.

Topical cream, ointment or gel

On the skin
Brands Diprolene
How this form is used
What it may be used for
  • Diprolene Ointment relieves inflammation and itching from corticosteroid-responsive skin conditions in patients 13 and older.
  • Betamethasone dipropionate gel (augmented) is used for the same purpose and is not recommended under age 12.
Important instructions
  • Diprolene Ointment is applied as a thin film once or twice daily.
  • Diprolene Ointment is for the skin only, not for the mouth, eyes or vagina.
  • Diprolene Ointment should not be used with occlusive dressings unless a physician directs it.
  • Betamethasone dipropionate gel (augmented) should not be used beyond two consecutive weeks.
Available strengths 5 strengths
0.5 mg/g 0.5 mg/mL 1 mg/g 1 mg/mL 1.2 mg/g
136 FDA-listed product records ⓘ

Inhaler

On the skin
Available strengths 1 strength
1.2 mg/g
8 FDA-listed product records ⓘ

Topical spray

On the skin
Brands Sernivo
How this form is used
What it may be used for
  • Sernivo Spray treats mild to moderate plaque psoriasis in adults 18 and older.
  • Betamethasone dipropionate spray has the same use in adults 18 and older.
Important instructions
  • Sernivo Spray should be shaken well, applied twice daily and rubbed in gently.
  • Sernivo Spray should be used for up to 4 weeks only.
  • Sernivo Spray should not be used on the face, scalp, underarms, groin or other skin-fold areas.
  • Sernivo Spray should not be covered or bandaged unless a physician directs it.
Available strengths 1 strength
0.5 mg/g
5 FDA-listed product records ⓘ

Betamethasone on the U.S. market: products, makers and brands

How Betamethasone appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

29 companies list 79 Betamethasone product records with the FDA, mostly as topical cream, ointment or gel, inhaler, topical spray; the earliest marketing or approval year on record is 1961. Brand names on the directory include Luxiq, Betavet, Sernivo and 2 more; the rest are generics.

3
Dose forms ⓘ
29
Labelers (makers, repackagers, distributors)
4
Brand names
79
FDA-listed product records ⓘ
1961
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (44) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

A-S Medication Solutions16%
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC10%
Bryant Ranch Prepack9%
Sun Pharmaceutical Industries, Inc.9%
Preferred Pharmaceuticals, Inc.6%
Cosette Pharmaceuticals, Inc.5%
Other makers44%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Betamethasone is used (Medicaid data)

A general measure of how commonly Betamethasone is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Betamethasone is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

403,381
Medicaid prescriptions filled (Q1–Q4 2025)
$11.3M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Betamethasone prescribed? Of the 1,601 medications we measure, Betamethasone ranks #288 by Medicaid prescriptions — more than 82% of them.

Where Betamethasone ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #288 of 1,601
#283 Varenicline 417,684 Rx #284 Human Insulin Injectio... 414,373 Rx #285 Loperamide 409,237 Rx #286 Tacrolimus Topical 408,485 Rx #287 Cyclosporine 403,927 Rx #288 Betamethasone 403,381 Rx #289 Betamethasone Topical 402,754 Rx #290 Midazolam 401,717 Rx #291 Zonisamide 395,289 Rx #292 Methimazole 378,542 Rx #293 Cyclosporine Ophthalmi... 377,528 Rx

Utilization by Betamethasone product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 0.5 mg/mL topical cream is the most-dispensed Betamethasone product — about 26% of these Medicaid prescriptions.

betamethasone 0.5 MG/ML Topical Cream Most dispensed

104,669 Medicaid prescriptions (Q1–Q4 2025) 26% of Betamethasone prescriptions shown $3.2M gross reimbursement (before rebates) ≈ $30 per prescription (gross)

Summed across the 12 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 238920

betamethasone 1 MG/ML Topical Cream

92,311 Medicaid prescriptions (Q1–Q4 2025) 23% of Betamethasone prescriptions shown $2.2M gross reimbursement (before rebates) ≈ $24 per prescription (gross)

Summed across the 6 of 23 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197407

betamethasone 0.0005 MG/MG Topical Ointment

53,062 Medicaid prescriptions (Q1–Q4 2025) 13% of Betamethasone prescriptions shown $1.7M gross reimbursement (before rebates) ≈ $33 per prescription (gross)

Summed across the 10 of 21 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197405

betamethasone 0.001 MG/MG Topical Ointment

45,581 Medicaid prescriptions (Q1–Q4 2025) 11% of Betamethasone prescriptions shown $1.2M gross reimbursement (before rebates) ≈ $27 per prescription (gross)

Summed across the 4 of 10 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197409

Augmented betamethasone 0.5 MG/ML Topical Cream

41,072 Medicaid prescriptions (Q1–Q4 2025) 10% of Betamethasone prescriptions shown $527,082 gross reimbursement (before rebates) ≈ $13 per prescription (gross)

Summed across the 4 of 26 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 848176

betamethasone 0.5 MG/ML Topical Lotion

30,159 Medicaid prescriptions (Q1–Q4 2025) 7% of Betamethasone prescriptions shown $790,166 gross reimbursement (before rebates) ≈ $26 per prescription (gross)

Summed across the 3 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 240209

Augmented betamethasone 0.0005 MG/MG Topical Ointment

20,361 Medicaid prescriptions (Q1–Q4 2025) 5% of Betamethasone prescriptions shown $948,216 gross reimbursement (before rebates) ≈ $47 per prescription (gross)

Summed across the 10 of 25 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 848180

betamethasone 1 MG/ML Topical Lotion

11,914 Medicaid prescriptions (Q1–Q4 2025) 3% of Betamethasone prescriptions shown $522,603 gross reimbursement (before rebates) ≈ $44 per prescription (gross)

Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197408

Augmented betamethasone 0.5 MG/ML Topical Lotion

3,460 Medicaid prescriptions (Q1–Q4 2025) <1% of Betamethasone prescriptions shown $156,723 gross reimbursement (before rebates) ≈ $45 per prescription (gross)

Summed across the 4 of 12 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 848178

betamethasone valerate 1.2 MG/ML Topical Foam

627 Medicaid prescriptions (Q1–Q4 2025) <1% of Betamethasone prescriptions shown $51,084 gross reimbursement (before rebates) ≈ $81 per prescription (gross)

Summed across the 6 of 14 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1244634

Augmented betamethasone 0.0005 MG/MG Topical Gel

165 Medicaid prescriptions (Q1–Q4 2025) <1% of Betamethasone prescriptions shown $15,840 gross reimbursement (before rebates) ≈ $96 per prescription (gross)

Summed across the 2 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 848208

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Betamethasone, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 62 of 171 listed Betamethasone NDCs with Medicaid activity.

Compare Betamethasone products

A representative set of FDA-listed product records for Betamethasone — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 79 of 79 products — FDA National Drug Code Directory. See every product, package size and price: browse all 79 Betamethasone NDCs →

Betamethasone recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list one Betamethasone recall since July 2021. It is no longer listed as ongoing. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Class II Apr 13, 2022 · Terminated · Mckesson Medical-Surgical Inc. Corporate Office
cGMP deviations: Temperature abuse
  • Betamethasone Dipropionate Cream USP, 0.05%, 45 grams tube, Rx only, MFG: Sandoz Pharma, NDC 0168-0055-46 Lots: McKesson Medical-Surgical (MMS) is not able to identify the particular lot number received by a particular consignee for the recalled prescription products. Each letter includes the date it was distributed to customers and the dates that i… FDA record D-1028-2022 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Betamethasone RxCUI 1514 13 dose forms · 22 strengths
  1. Dose form (SCDF) Disintegrating Oral Tablet RxCUI 379265 No current FDA listing
    Clinical drug / strength (SCD) 0.5 MG RxCUI 105389
  2. Dose form (SCDF) Injectable Solution RxCUI 371049 No current FDA listing
    Clinical drug / strength (SCD) 4 MG/ML RxCUI 308718
  3. Dose form (SCDF) Injectable Suspension RxCUI 378340 No current FDA listing
    Clinical drug / strength (SCD) 6 MG/ML RxCUI 1660745
  4. Dose form (SCDF) Ophthalmic Ointment RxCUI 376457 No current FDA listing
    Clinical drug / strength (SCD) 0.001 MG/MG RxCUI 249596
  5. Dose form (SCDF) Oral Solution RxCUI 371053 No current FDA listing
    Clinical drug / strength (SCD) 0.12 MG/ML RxCUI 670084
  6. Dose form (SCDF) Oral Tablet RxCUI 371056 No current FDA listing
    Clinical drug / strength (SCD) 0.5 MG RxCUI 245258 0.6 MG RxCUI 308709
  8. Dose form (SCDF) Topical Foam RxCUI 384499 In current FDA listings
    Clinical drug / strength (SCD) valerate 1.2 MG/ML RxCUI 1244634
  9. Dose form (SCDF) Topical Gel RxCUI 377967 In current FDA listings
    Clinical drug / strength (SCD) Augmented betamethasone 0.0005 MG/MG RxCUI 848208 0.0005 MG/MG RxCUI 240571
  12. Dose form (SCDF) Topical Solution RxCUI 371057 No current FDA listing
    Clinical drug / strength (SCD) 1 MG/ML RxCUI 250861
  13. Dose form (SCDF) Topical Spray RxCUI 377311 In current FDA listings
    Clinical drug / strength (SCD) 0.5 MG/ML RxCUI 1738536

Look up RxCUI 1514 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Betamethasone costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Cream · Topical 0.5 mg/g $0.371–$0.465 per gram NDC details & price history
Cream · Topical 1 mg/g $0.348–$0.415 per gram NDC details & price history
Cream · Topical 1.2 mg/g $0.348–$0.415 per gram NDC details & price history
Ointment · Topical 0.5 mg/g $0.349–$0.460 per gram NDC details & price history
Ointment · Topical 1 mg/g $0.492–$0.614 per gram NDC details & price history
Ointment · Topical 1.2 mg/g $0.492–$0.614 per gram NDC details & price history
Ointment, Augmented · Topical 0.5 mg/g $0.535–$0.588 per gram NDC details & price history
Lotion · Topical 0.5 mg/mL $0.292 per mL NDC details & price history
Lotion · Topical 0.5 mg/g $0.292 per mL NDC details & price history
Lotion · Topical 1 mg/mL $0.452 per mL NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Betamethasone brand names

Betamethasone is sold under 5 brand names in the FDA directory — Luxiq, Betavet, Sernivo, Del-Beta and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Luxiq Betavet Sernivo Del-Beta Diprolene

Who makes Betamethasone: manufacturers and labelers

29 companies list Betamethasone products with the FDA. By number of product records, the largest are A-S Medication Solutions, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, Bryant Ranch Prepack. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

A-S Medication Solutions 13 E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC 8 Bryant Ranch Prepack 7 Sun Pharmaceutical Industries, Inc. 7 Preferred Pharmaceuticals, Inc. 5 Cosette Pharmaceuticals, Inc. 4 NuCare Pharmaceuticals,Inc. 4 Padagis Israel Pharmaceuticals Ltd 4 Actavis Pharma, Inc. 3 Proficient Rx LP 3 Aurobindo Pharma Limited 2 Zydus Lifesciences Limited 2 Alembic Pharmaceuticals Inc. 1 Alembic Pharmaceuticals Limited 1 Asclemed USA, Inc 1 Burel Pharmaceuticals, LLC 1 Encube Ethicals, Inc. 1 Glenmark Pharmaceuticals Inc., USA 1 Golden State Medical Supply, Inc. 1 Lupin Pharmaceuticals, Inc. 1 Northstar Rx LLC. 1 Organon LLC 1 Prasco Laboratories 1 Primus Pharmaceuticals, Inc. 1

…and 5 more on the FDA NDC directory.

Betamethasone drug class (RxNorm)

Betamethasone belongs to the Corticosteroid class.

Pharmacologic class Corticosteroid
Drug family (ATC) Corticosteroids acting locally, Corticosteroids, Corticosteroids, potent (group III)
How it works Corticosteroid Hormone Receptor Agonists

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Betamethasone page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Apr 22, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Betamethasone.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Betamethasone after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
83
Finished products in the current FDA directory
79
Companies listing them (makers, repackagers, distributors)
29
FDA labeler codes behind them ⓘ
31
Linked representative label ⓘ
Primus Pharmaceuticals, Inc.
Linked label effective
Apr 22, 2026
Composite sections available
22
Linked SPL Set ID
b1b3d1b0-da9b-11eb-ad76-0800200c9a66
Linked SPL Document ID
8310ee9a-2de4-4246-a1ed-6fd23d041962
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Primus Pharmaceuticals, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →