Medications That May Deplete STRONTIUM
See which medications carry a reported association, how strong the evidence is, and what to discuss with your pharmacist.
Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fracture risk but carries serious heart-related safety concerns, while the over-the-counter supplement form (strontium citrate) has much less evidence. Talk to your doctor or pharmacist before using it, especially if you have heart disease or are at risk for blood clots.
Commonly used for: Bone health and osteoporosis, Reducing fracture risk, Tooth sensitivity (in some toothpastes), Supporting bone density.
HelloPharmacist pharmacist-reviewed education. The medication records below are licensed clinical data, shown as published.
Deep dive: Strontium — uses, safety & drug interactions
Medications associated with STRONTIUM depletion
Each record is shown as published in our licensed clinical database. Open a medication for its full nutrient report.
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Azelastine Hydrochloride, Fluticasone Propionate
Insufficient EvidenceBrand names include Dymista
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and some research hints that high doses of oral corticosteroids may cause the kidneys to excrete more of it in urine. Fluticasone in this nasal spray, though, is absorbed into the body at very low levels compared to the oral steroid doses studied, so any effect on strontium is purely theoretical here. There is not enough evidence to know whether this combination matters at all in practice, and most people using this nasal spray have no reason to be concerned. If you are curious or have questions about your mineral levels, your doctor or pharmacist is a good place to start.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Full nutrient report for Azelastine Hydrochloride, Fluticasone Propionate →
Beclometasone dipropionate
Insufficient EvidenceBrand names include Becotide
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it plays a minor role in bone metabolism. Some early research found that high doses of corticosteroids caused the kidneys to excrete more strontium in the urine, which could theoretically lower body levels over time. That said, beclometasone is typically inhaled at much lower doses than the oral steroids studied, so any effect is likely to be quite small. The evidence here is rated insufficient, meaning there really is not enough data to know if this matters in practice, and most people using this medication do not need to take any action.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Beclomethasone
Insufficient EvidenceBrand names include Beclovent, Vanceril
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it may play a small role in bone health. Some early research found that corticosteroids like beclomethasone could cause the kidneys to release more strontium in the urine, suggesting the body may hold onto less of it over time. That said, the evidence here is genuinely thin, so this is more of an open question than a proven concern. If you use inhaled beclomethasone regularly and have questions about your bone health in general, that is worth a conversation with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Beclomethasone dipropionate
Insufficient EvidenceBrand names include Qvar, QNASL
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it plays a minor role in bone structure. Some early research found that high doses of corticosteroids, the drug class beclomethasone belongs to, may cause the kidneys to excrete more strontium in the urine than usual. That said, the evidence here is quite limited and comes from studies using much higher steroid doses than most people take with beclomethasone, so the real-world significance for you is simply unknown. If you have lingering questions, your pharmacist or doctor is a good place to start.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Betamethasone
Insufficient EvidenceBrand names include Celestone, Diprolene AF, Diprosone
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a mineral that the body handles similarly to calcium, and it plays a small role in bone health. Some early research found that high doses of corticosteroids like betamethasone may cause the kidneys to flush more strontium out through the urine, which could gradually lower levels in the body. That said, the evidence here is quite limited, and right now no one really knows whether this matters clinically. Given the 'insufficient evidence' rating, there is no reason to worry, but if you have been on betamethasone long-term at higher doses, it is worth mentioning to your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Betamethasone Dipropionate
Insufficient EvidenceBrand names include Sernivo
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a mineral that the body handles similarly to calcium, and it plays a small supporting role in bone health. Some early research found that high doses of corticosteroids like prednisone caused the kidneys to flush out more strontium in the urine, which could theoretically lower levels over time. That said, the evidence for betamethasone dipropionate specifically is very thin, and no one knows yet whether this matters clinically. For now, there is nothing you need to do about this, but if you are a long-term user and have bone health concerns, it is worth a quick conversation with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Betamethasone Dipropionate, Calcipotriene
Insufficient EvidenceBrand names include Enstilar, Wynzora
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body uses in small amounts, particularly in bone tissue, though its exact role in human health is still being studied. Some research has found that high oral doses of corticosteroids can cause the kidneys to excrete more strontium in the urine, which is where this concern comes from. That said, the calcipotriene and betamethasone dipropionate combination is applied to the skin, not taken by mouth, so systemic absorption is much lower than with oral steroids. Right now there is not enough evidence to know whether this matters in practice, so no action is generally expected, but your pharmacist or doctor is always a good resource if you have questions.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Full nutrient report for Betamethasone Dipropionate, Calcipotriene →
Betamethasone valerate
Insufficient EvidenceBrand names include Luxiq
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and some research hints that corticosteroids like betamethasone valerate may cause the kidneys to flush more of it out in the urine. That said, the available evidence here is quite limited, and whether this actually causes any meaningful change in the body is simply not known. For most people using betamethasone valerate, this is not something to worry about, but if you have questions or take this medication long-term, your pharmacist or doctor is a good person to check in with.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Budesonide
Insufficient EvidenceBrand names include Entocort EC, Pulmicort, Uceris
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a mineral that the body handles similarly to calcium, and some research suggests it may play a small role in bone health. There is limited data from studies using high-dose corticosteroids showing that the kidneys may excrete more strontium in the urine during treatment, which could theoretically lower levels in the body. That said, the evidence here is rated as insufficient, so we really do not know whether budesonide causes a meaningful change in strontium status for most people. This is not something to worry about on your own, but if you have questions about your bone health while taking budesonide long-term, it is worth bringing up with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Clobetasol
Insufficient EvidenceBrand names include Temovate, Clobex
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a mineral that the body handles similarly to calcium, and it may play a small role in bone health. Some early research hints that corticosteroids like clobetasol could cause the kidneys to release more strontium in the urine than usual, nudging levels downward over time. That said, the evidence here is thin and the real-world impact is simply not known, so this is firmly in the 'we are not sure it matters' category. If you use clobetasol regularly and have questions about your bone health or mineral levels, it is worth raising with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Cortisone Acetate
Insufficient EvidenceBrand names include Cortone, Cortisone Tablets
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it shows up mostly in bones. Some early research found that high doses of corticosteroids like cortisone may cause the kidneys to release more strontium in the urine than usual, which could nudge levels down over time. That said, the evidence here is quite limited, and right now no one knows whether this is actually meaningful for your health. If you have questions or take corticosteroids long-term, it is worth mentioning to your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Dexamethasone
Insufficient EvidenceBrand names include Decadron, Hexadrol, Dexone
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body stores mostly in bone, where it may play a small role alongside calcium in keeping bones dense. Some early research found that high doses of corticosteroids like dexamethasone seem to make the kidneys release more strontium in the urine, which could gradually lower what the body holds onto. That said, the evidence here is quite limited, and experts simply do not yet know whether this matters for your health. For now, there is nothing you need to act on, but if you are curious or taking dexamethasone long term, it is a reasonable thing to mention to your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Fludrocortisone
Insufficient EvidenceBrand names include Florinef Acetate
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it may play a small role in bone health. There is some early data suggesting that corticosteroids like fludrocortisone could cause the kidneys to flush out more strontium in the urine, but this comes from studies using fairly high doses of other corticosteroids and the findings are quite preliminary. Honestly, the evidence here is too thin to know whether this matters at all in practice, so most people on fludrocortisone do not need to worry about it. If you have questions or concerns, your pharmacist or doctor is a great first stop.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Fluticasone
Insufficient EvidenceBrand names include Flovent, Flonase, Flixotide
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it plays a small role in bone health. Some early research found that high doses of corticosteroids like prednisone can cause the kidneys to excrete more strontium in the urine, which could theoretically lower levels over time. Fluticasone is an inhaled or topical corticosteroid, and whether the relatively low amounts absorbed into the body from those forms would have any meaningful effect on strontium is simply not known. The evidence here is too limited to draw conclusions, so most people using fluticasone do not need to worry about this, but if you have concerns, your pharmacist or doctor is a good person to ask.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Fluticasone Furoate, Umeclidinium, Vilanterol
Insufficient EvidenceBrand names include Trelegy Ellipta
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it shows up naturally in bone tissue. The corticosteroid component of this inhaler (fluticasone furoate) is related to steroid medications that, in limited research using high oral doses, appeared to cause the kidneys to flush out more strontium in the urine. That said, the dose in an inhaled combination product like this one is far lower than what those studies used, and right now there simply is not enough evidence to know whether this matters in practice. Most people using this inhaler do not need to worry about strontium levels, but if you have questions, your pharmacist or doctor is a great place to start.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Full nutrient report for Fluticasone Furoate, Umeclidinium, Vilanterol →
Fluticasone Furoate, Vilanterol Trifenatate
Insufficient EvidenceBrand names include Breo Ellipta
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral your body stores mainly in bone, where it plays a small supporting role alongside calcium in keeping bones dense. There is some early research suggesting that high doses of corticosteroids, the drug class fluticasone furoate belongs to, may cause the kidneys to flush out more strontium in the urine. That said, the doses in those studies were much higher than what you typically get from an inhaled combination product like this one, and right now there simply is not enough evidence to know whether this matters at all in practice. Most people using this inhaler do not need to worry about strontium, but if you have questions about bone health while on a long-term inhaled corticosteroid, your pharmacist or doctor is a good place to start.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Full nutrient report for Fluticasone Furoate, Vilanterol Trifenatate →
Hydrocortisone
Insufficient EvidenceBrand names include Cortef, Hydrocortone, Carmol HC cream
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and some early research hints that high doses of corticosteroids like hydrocortisone may cause the kidneys to flush more of it out in the urine. That said, the evidence here is quite limited, and no one really knows yet whether this matters clinically. For most people taking hydrocortisone, there is nothing to worry about right now, but if you have questions about your mineral levels, it is always worth a conversation with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Methylprednisolone
Insufficient EvidenceBrand names include Medrol, Medrol Dosepak
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that your bones absorb and store, and researchers have noted that high doses of corticosteroids like methylprednisolone may cause the kidneys to flush more of it out in the urine. That said, the evidence here is quite limited, and nobody yet knows whether this shift actually causes a meaningful problem in people. Right now this falls into the 'we don't have enough information to say it matters' category, so there's nothing specific you need to do, but if you have questions about your bone health while on this medication, it's worth bringing up with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Olopatadine Hydrochloride, Mometasone Furoate
Insufficient EvidenceBrand names include Ryaltris
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body uses in small amounts, particularly in bone tissue. The mometasone in this combination is a corticosteroid, and some early research found that high oral doses of corticosteroids can cause the kidneys to excrete more strontium in the urine. That said, mometasone here is used as a nasal spray, meaning very little of it is absorbed into the bloodstream, so any effect on strontium is considered theoretical at best. The evidence on this is truly too thin to draw conclusions, and most people using this nasal spray do not need to worry about it, though your pharmacist or doctor can always address any concerns.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Full nutrient report for Olopatadine Hydrochloride, Mometasone Furoate →
Prednisolone
Insufficient EvidenceBrand names include Sterane, Delta Cortef, Cortalone
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it may play a small role in bone health. Some early research found that higher doses of corticosteroids like prednisolone can cause the kidneys to release more strontium in the urine, which could gradually lower levels in the body. That said, the evidence here is quite limited, and the real-world significance is simply not known yet. If you have concerns, it is worth mentioning to your pharmacist or doctor, but this is not something most people on prednisolone need to worry about right now.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Prednisone
Insufficient EvidenceBrand names include Deltasone, Cortan, Orasone
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it may play a small role in bone health. Some early research found that higher doses of corticosteroids like prednisone seem to cause the kidneys to flush more strontium out in the urine, which could nudge levels lower over time. That said, the evidence here is quite limited, and nobody yet knows whether this has any real effect on your health. This one is firmly in the 'we just don't know enough yet' category, so there is no action most people need to take, though your doctor or pharmacist is always a good sounding board if you have questions.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Triamcinolone
Insufficient EvidenceBrand names include Aristocort, Kenacort, Adcortyl Intra-articular / Intradermal
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and some early research hints that corticosteroids like triamcinolone may cause the kidneys to release more of it in the urine than usual. That said, the evidence here is quite limited and comes from studies using relatively high doses, so we really do not know whether this matters clinically. Given the 'Insufficient Evidence' rating, there is no established reason to worry, but if you are curious about your mineral levels while on long-term triamcinolone, it is worth bringing up with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
Triamcinolone Acetonide
Insufficient EvidenceBrand names include Zilretta, Xipere
Limited data suggest urinary strontium excretion is increased after 5-6 weeks of treatment with high doses of corticosteroids (e.g., hydrocortisone 80-120 mg/day, prednisone 20-30 mg/day, dexamethasone 3mg/day, triamcinolone 12-18 mg/day). The clinical significance of this is unknown.
Strontium is a trace mineral that the body handles similarly to calcium, and it may play a small role in bone health. Some early research found that higher doses of corticosteroids like triamcinolone seem to make the kidneys excrete more strontium in the urine, suggesting the drug may cause the body to flush it out faster. That said, the evidence here is quite thin, and nobody yet knows whether this has any real health impact. This is listed as insufficient evidence, so most people using triamcinolone do not need to worry about it, though you are always welcome to bring it up with your pharmacist or doctor.
References (1)
- Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
This tool is educational and is not a substitute for professional medical advice. An association is not a diagnosis and does not mean a deficiency will occur. Always talk to your pharmacist or healthcare provider before starting, stopping, or changing any medication or supplement.
Disclaimer: This checker finds which nutrients might be depleted by prescription or over-the-counter medications. Each nutrient depletion issue is rated based on clinical significance. Use your own professional judgment prior to making clinical decisions.© 2026 Therapeutic Research Center Licensed records refresh weekly · last updated July 3, 2026.
What drug-induced nutrient depletion means
Some medications can, over time, lower the levels of certain vitamins, minerals, or other nutrients — through reduced absorption, increased loss, or changes in how the body uses them.
Association is not deficiency
An entry here means a depletion has been reported or studied — not that it happens to everyone, or that you are deficient. Dose, duration, diet, and your own health all matter.
Evidence varies by pair
Some drug–nutrient links (like metformin and vitamin B12) are well studied; others rest on limited or preliminary research. Each entry shows the evidence rating from our licensed clinical database.
When to ask about labs
If you take an associated medication long-term, ask your healthcare provider whether monitoring is appropriate for you. Not everyone needs testing — your provider can weigh your dose, duration, and symptoms.
Don't self-supplement blindly
Supplements are not risk-free: some can interact with medications, and some (like potassium or magnesium) can be risky with kidney disease. Talk to your pharmacist before adding anything.
Never stop a medication over this
These medications are prescribed for good reasons, and the benefit usually far outweighs a manageable nutrient consideration. Any change belongs in a conversation with your prescriber.
Food first, usually
For many nutrients, a varied diet covers the gap. Each entry lists common food sources; a supplement is a decision to make with your pharmacist or provider, not a default.
STRONTIUM & medications: FAQs
Which medications can lower STRONTIUM?
I take one of these medications — am I deficient in STRONTIUM?
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Where does this information come from?
Other commonly implicated nutrients
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Sources & How We Checked
Medication associations with STRONTIUM are evidence-graded and sourced from the Natural Medicines database, and are displayed as published with their citations.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for drug-induced nutrient depletions, supplements, and interactions — the basis for this page.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for medication overviews across the site.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.