Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Aletris Root Ingredients & Drug Interactions

by Indiana Botanic Gardens

Aletris Root label
See full label image
Unknown Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aletris Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Aletris Root is a dietary supplement by Indiana Botanic Gardens with 2 active ingredients. Its ingredients are commonly taken for menstrual complaints, digestive upset and colic, loss of appetite.Based on those ingredients, 77 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aletris root cut. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Aletris Root by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Aletris Root by Indiana Botanic Gardens — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Aletris Root by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: aletris root, in cut form. Aletris is a traditional botanical with a long history in herbal practice, though modern safety and effectiveness research is limited.

There are no inactive ingredients listed for this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Aletris product and its label doesn't state a use — see Aletris's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness data on file for aletris root. The facts don't outline what this ingredient is intended to treat or whether clinical evidence supports its use for any particular condition.

The evidence, ingredient by ingredient Aletris

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Aletris root has limited modern safety data, and large or fresh doses may cause stomach upset. Oral use has been reported to cause colic (abdominal cramping), stupefaction (drowsiness or confusion), and vertigo (dizziness) in small doses, though reports are sparse.

Because aletris has traditionally been linked to uterine and hormonal effects, the safety data advises against use during pregnancy. There isn't enough reliable information to know whether it's safe while breastfeeding—talk with your doctor or pharmacist before taking it if you're pregnant or nursing.

Side effects, ingredient by ingredient Aletris

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Aletris.
  • The most serious interaction on file is rated Moderate.
  • For scale: 77 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take estrogen medications (birth control, hormone therapy), check with your doctor or pharmacist before starting—aletris may have estrogenic effects. Also double-check if you use H2-blockers, antacids, or proton pump inhibitors for heartburn or reflux; aletris could reduce how well they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Aletris root is a traditional botanical with limited modern research. If you take estrogen medications, stomach acid–reducing drugs, or have concerns about hormonal effects, check with your doctor or pharmacist before adding this to your routine.

Because it may raise stomach acid and has sparse safety data, start low if you do use it, and stop if you feel dizzy, confused, or crampy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aletris Root, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308210019
Net contents 1 oz.
Market status On market
Date entered into DSLD Dec 23, 2011
DSLD ID 3338
Product type Botanical
Supplement form Unknown
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aletris Root by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 g, 1 Teaspoon(s)
Maximum serving Sizes:
2 g, 1 Teaspoon(s)
Servings per container
17
UPC/BARCODE
703308210019
IngredientAmount% DV
Calories6 {Calories}--
Carbohydrates1 g1%
Aletris root cut2 g--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

Precautions

KEEP OUT OF REACH OF CHILDREN

Warning: If you are using this product for any other purpose than as a spice, tea or seasoning please read the following warning: If you are using any medications or are pregnant or nursing, do not use prior to consulting a physician.

General Statements

(Cut)

Lot# 6070846

Seals/Symbols

IBG INDIANA BOTANIC GARDENS(R)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aletris Root by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aletris Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aletris Root by Indiana Botanic Gardens

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 g Dosage formUnknown Servings per container17 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Carbohydrates

1 g per serving

Aletris root cut

Interacts with
77 drugs
2 g per serving

Aletris (true unicorn root or colic root) is a North American herb traditionally used for menstrual problems and digestive complaints, but there is li...

Aletris root cut monograph & interactions
Interaction report

Aletris Root by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Aletris Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
77Drugs
41 Moderate 36 Minor

Ingredients driving the most interactions

Aletris root cut 77

Individual Drug Interactions

The ingredients in Aletris Root interact with 77 drugs. Click any drug to see the details.

1 of the 2 ingredients in Aletris Root interact with drugs. Each result below shows which ingredient is responsible. Aletris root cut

Each ingredient & the kinds of drugs it affects

For each ingredient in Aletris Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aletris root cut4 drug types · 77 drugs

Estrogens

Aletris might have estrogenic effects. Theoretically, use of aletris with estrogens might increase the risk for additive adverse effects.

Likelihood Possible Evidence D
Antacids

Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of antacids.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of H2-blockers. The H2 blockers include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, due to reports that aletris increases stomach acid, aletris might decrease the effectiveness of PPIs. PPIs include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).

Likelihood Possible Evidence D
Aletris root cut full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aletris Root, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Aletris Root by Indiana Botanic Gardens: Common Questions

Does Aletris Root by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Aletris Root has a known interaction with 77 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aletris Root contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is aletris root used for?
We don't have data on file for what aletris is intended to treat. Talk with your healthcare provider or herbalist about why you're considering it and whether it's right for your situation.
Can I take this if I'm on birth control?
Not without checking first. Aletris may have estrogenic effects, so combining it with estrogen-containing birth control could raise the risk of unwanted hormonal effects. Ask your doctor or pharmacist whether it's safe for you.
What side effects does aletris have?
Reports are limited, but oral use has been linked to colic (stomach cramping), dizziness, and drowsiness or confusion. Large or fresh doses may cause stomach upset. Stop and contact your doctor if you feel dizzy or very uncomfortable.
Is it safe to take during pregnancy or while breastfeeding?
No. Aletris is traditionally linked to uterine and hormonal effects, so safety data advises against it during pregnancy. There isn't enough reliable information for breastfeeding either—talk with your doctor before taking it.
I take omeprazole for reflux—will aletris work with it?
Aletris may increase stomach acid, which could make omeprazole and other reflux medications less effective. Check with your doctor or pharmacist before combining them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Aletris Root is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aletris Root label
Go deeper

The Full Monographs Behind Aletris Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Aletris

Interacts with 77 drugs

Aletris (true unicorn root or colic root) is a North American herb traditionally used for menstrual problems and digestive complaints, but there is little to no modern human research to show...

Read the full Aletris monograph →
Sources

Sources & How We Checked

Aletris Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Aletris 4 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Aletris monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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