Estrogen
Estrogen, as described in the supplied product evidence, is a product for external use on the skin, applied to clean skin twice daily as part of a skincare routine.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 1 clinical label set within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Estrogen, as labeled here, is a skin product applied to clean skin of the face, neck, or body twice daily alongside a daily skincare routine, and since its label names no medical condition, it is not the same as prescription estrogen hormone therapy. The label lists no specific side effects, and its cautions are about where the product ends up. It is for external use only, so never swallow it, keep it out of your eyes, and store it out of children's reach. If you have specific medical concerns, check with your pharmacist or prescriber before starting it.
Clinical pearls
- Wash and dry the face, neck, or body area first, since the label calls for clean skin at each twice-daily use.
- Check the carton's ingredient list, because the name alone does not tell you whether it contains an actual hormone.
- Because this product must never be swallowed, store it where children cannot reach or open it.
- Apply it away from the eye area, since the label specifically warns against getting it in your eyes.
Patient information guide A plain-language walkthrough of Estrogen, written from its FDA label.
What Estrogen is used for
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The supplied product information describes a skin-applied product, not a treatment for a named medical condition.
- Applied to clean skin on the face, neck, or body
- Used twice daily
- Meant to be combined with a daily skincare routine
Estrogen dosage
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This product is applied to clean skin on the face, neck, or body.
- Use it twice daily.
- Combine it with a daily skincare routine for best results.
- It is for external use only.
Follow your healthcare provider's advice and the product label.
Dosing details from the FDA-approved label
From the Estrogen prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
Read the label’s full dosing text
50G/1.76OZ
Read the full Dosage and Administration section on DailyMed →
Estrogen warnings and precautions
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- For external use only. Do not swallow it.
- Avoid contact with your eyes.
- Keep out of reach of children.
- Talk with your healthcare provider before use if you have specific medical concerns.
Before taking Estrogen
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- Check with your healthcare provider first if you have specific medical concerns.
- Keep the product out of reach of children.
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & herbs that interact with Estrogen
212 supplements and herbal products have documented interactions with Estrogen in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 3
- Moderate · 174
- Minor · 35
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient depletion considerations
Estrogen has been associated with lower levels of 5 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
- Higher significance · 3
- Moderate · 2
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
Estrogen: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Estrogen — the kind of thing our pharmacy team would talk through with you at the counter.
What is this product used for?
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How often do I use it?
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Can I swallow it or use it on my eyes?
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Is it safe to keep at home with kids around?
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Should I talk to someone before I start?
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Is Estrogen available over the counter?
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When was Estrogen first available?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Estrogen on HelloPharmacist
Estrogen forms and strengths (how it comes)
Estrogen is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Topical cream, ointment or gel
Estrogen on the U.S. market: products, makers and brands
How Estrogen appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
1 company lists 1 Estrogen product record with the FDA, mostly as topical cream, ointment or gel; the earliest marketing or approval year on record is 2025. Brand names on the directory include Arthcal ESTROGEN; the rest are generics.
Compare Estrogen products
A representative set of FDA-listed product records for Estrogen — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Topical cream, ointment or gel | ||||
| 0.2 g/100 mL | Cutaneous | Beijing JUNGE Technology Co., Ltd. | ANDA | View NDC → |
Showing 1 of 1 products — FDA National Drug Code Directory. See every product, package size and price: browse all 1 Estrogen NDCs →
Estrogen side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Estrogen — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Estrogen in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Estrogen FDA approval history
How Estrogen went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Estrogen recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list no Estrogen recalls since July 2021.
✅No Estrogen recalls on record since July 2021Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.
Estrogen supply and shortage status
Whether Estrogen is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
Estrogen brand names
Estrogen is sold under one brand name in the FDA directory — Arthcal ESTROGEN. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Estrogen: manufacturers and labelers
One company lists Estrogen products with the FDA. By number of product records, the largest are Beijing JUNGE Technology Co., Ltd.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
Estrogen drug class (RxNorm)
Estrogen belongs to the Androgens and estrogens class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Estrogen page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Beijing JUNGE Technology Co., Ltd. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →