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Dietary supplement

AlivEL 100 50 mg Ingredients & Drug Interactions

by OptiChoice

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

AlivEL 100 50 mg is a dietary supplement by OptiChoice with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AlivEL 100 Eurycoma longifolia 100:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of AlivEL 100 50 mg by OptiChoice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

AlivEL 100 contains one active ingredient: Eurycoma longifolia extract, prepared as a 100:1 concentration at 50 mg per capsule. This is a plant extract from Southeast Asian traditional medicine, standardized for potency.

The capsule itself is made from vegetable material, and rice powder is used as a filler to give the capsule its form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: increase stamina, energy, sexual performance.
  • We looked for evidence on: Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Sexual desire, testosterone support — and 2 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Male Infertility.

The evidence for Eurycoma longifolia in this product is mixed. It's rated possibly effective for sexual desire, meaning some research supports its use for that purpose.

For athletic performance, the data suggests it's possibly ineffective. For back pain, osteoporosis, and diabetes, we don't have enough reliable evidence to know whether it works or doesn't — the research just isn't solid enough yet.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eurycoma longifolia is generally well tolerated in short-term studies, but long-term safety data and product quality standards aren't well established. The extract can raise testosterone levels; if they climb above normal, you could develop testosterone-related side effects like acne, insulin resistance, or liver stress.

For this reason, the safety data advises against use during pregnancy and breastfeeding — there isn't enough information to know it's safe in those situations.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this, check if you're on propranolol (or related beta-blockers) — the extract can reduce how well it works. Also double-check any medications metabolized by CYP1A2, CYP2C19, or CYP2A6 enzymes, and any testosterone therapy or supplementation.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

AlivEL 100 may be worth considering if you're interested in sexual desire support and don't take propranolol or testosterone-based treatments. If you're on any prescription medications, especially for the heart or blood pressure, or any hormone therapies, talk to your pharmacist before starting this — the interaction with propranolol is real, and several others are theoretical but worth ruling out.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AlivEL 100 50 mg, straight from the product label.

Brand OptiChoice
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 216954
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AlivEL 100 50 mg by OptiChoice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
IngredientAmount% DV
AlivEL 100 Eurycoma longifolia 100:1 extract50 mg--

Other ingredients: Rice powder, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Increase stamina AlivEL 100 boosts energy levels, improves sexual performance, and increases stamina. In clinical studies, AlivEL 100 has been shown effective in supporting healthy and normal cortisol and testosterone levels naturally. Exclusively endorsed by Dr. Johari Saad, "The King of Tongkat Ali," AlivEL 100 is created utilizing a proprietary natural water extraction process that produces one of the most effective, biologically active, and highest potency Tongkat Ali extracts available.

Supports optimal sexual performance Builds & tones muscles Regulates body fat

Boosts energy

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Eurycoma Longifolia

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-2 capsules per day or as directed by your health care professional or pharmacist.

Storage

Storage: Keep tightly closed in a cool, dry place in the original container. Do not expose to excessive heat.

Precautions

Keep out of the reach of children.

Caution: Do not use if seal is broken. As with all dietary supplements, consult a medical professional before using if you have an existing medical condition.

Brand IP Statement(s)

AlivEL 100 is a registered trademark of SOURCE GLOBAL PARTNERS and Vcaps is a registered trademark of Capsugel. For more information, please visit www.source-1-global.com

Seals/Symbols

Vcaps

See for yourself

AlivEL 100 50 mg by OptiChoice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in AlivEL 100 50 mg by OptiChoice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

50 mg per serving Form: Eurycomanone, Glycol protein, Polysaccharides

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

AlivEL 100 Eurycoma longifolia 100:1 extract monograph & interactions

Other (inactive) ingredients: Rice powder, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

AlivEL 100 50 mg by OptiChoice Drug Interactions

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248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in AlivEL 100 50 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AlivEL 100 Eurycoma longifolia 100:1 extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for AlivEL 100 50 mg, from the product label.

OptiChoice

See all OptiChoice products
Name
OptiChoice The Natural Choice for Optimal Health
Street Address
445 E. Illinois ST.
City
Chicago
State
IL
ZipCode
60611
Phone Number
1-800-755-4996
Pharmacist Counseling Corner

AlivEL 100 50 mg by OptiChoice: Common Questions

Does AlivEL 100 50 mg by OptiChoice interact with any medications?
Yes. Based on its ingredients, AlivEL 100 50 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AlivEL 100 50 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Eurycoma longifolia, and what is it used for?
Eurycoma longifolia is a plant extract from Southeast Asia traditionally used to support sexual desire. In this product it's concentrated 100-fold at 50 mg per capsule. The evidence shows it's possibly effective for that use, though research on other claimed benefits is limited or unclear.
Is AlivEL 100 safe to use long-term?
Short-term use is generally well tolerated in studies, but we don't have solid long-term safety data. If the extract raises your testosterone above normal levels, you could develop side effects like acne, insulin resistance, or liver problems. Talk to your pharmacist about how long you plan to use it.
Can I take this while pregnant or breastfeeding?
No — the safety data advises against it during pregnancy because of the extract's possible hormonal effects. During breastfeeding, there isn't enough reliable safety information, so it's best to avoid it. Talk to your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.
Does this product have any fillers or inactive ingredients?
Yes. The capsule contains rice powder as a filler and is made of vegetable material. The only active ingredient is the Eurycoma longifolia extract itself.
Will this help my athletic performance?
The evidence for athletic performance is rated possibly ineffective, meaning research doesn't support that use. If you're interested in this product, sexual desire is the better-supported purpose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AlivEL 100 50 mg label
Sources

Sources & How We Checked

AlivEL 100 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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