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Dietary supplement

Cholesstrinol HPe 150 mg Ingredients & Drug Interactions

by OptiChoice

Cholesstrinol HPe 150 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cholesstrinol HPe 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Cholesstrinol HPe 150 mg is a dietary supplement by OptiChoice with 3 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, antioxidant support, liver health (fatty liver).Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are TocoSource Palm Tocotrienols. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cholesstrinol HPe 150 mg by OptiChoice

Ask about any prescription or over-the-counter medication and we check it for interactions with Cholesstrinol HPe 150 mg by OptiChoice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cholesstrinol HPe 150 mg by OptiChoice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Cholesstrinol HPe” is listed as a grouped ingredient — the label gives one combined amount (150 mg) without saying how much of each component you get.

Cholesstrinol HPe 150 mg contains three active ingredients. TocoSource Palm Tocotrienols is a form of vitamin E extracted from palm oil.

The product also includes PMF-source Citrus Flavones and ErioSource Eriocitrin, which are plant compounds from citrus. The capsule itself is made from vegetable material, with rice powder as an inactive filler.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Tocotrienols's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: heart health and healthy cholesterol and triglyceride levels.
  • We looked for evidence on: Hypercholesterolemia, Metabolic syndrome, dyslipidemia, cardiovascular disease.
  • The closest evidence on file: Tocotrienols is rated "Possibly Ineffective" for Hypercholesterolemia (Natural Medicines).
  • Also on file: Tocotrienols is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.

The tocotrienol in this product is rated possibly effective for diabetes and possibly ineffective for high cholesterol. For alopecia areata (hair loss) and breast cancer, there isn't enough reliable evidence to rate whether it works.

If you're taking this product for cholesterol, the evidence doesn't support that use.

The evidence, ingredient by ingredient Tocotrienols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tocotrienols are generally well tolerated in studies, though long-term safety at supplement doses isn't fully established. The safety data advises against using this product during pregnancy.

For breastfeeding, there isn't enough information — talk with your doctor or pharmacist before taking it if you're nursing. When taken by mouth, tocotrienols haven't caused any adverse effects in clinical trials.

Topically (applied to skin), a small number of trial participants reported mild itching.

Side effects, ingredient by ingredient Tocotrienols

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tocotrienols.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cholesstrinol HPe, double-check with your doctor or pharmacist if you're on anticoagulant or antiplatelet medications — blood thinners and drugs that prevent clotting — because tocotrienols may increase bleeding risk, even though it hasn't been seen in humans yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

If you're considering this product for diabetes, there's some evidence it may help. If you're taking blood thinners or antiplatelet drugs, check with your doctor or pharmacist first — there's a theoretical bleeding risk.

Avoid it during pregnancy, and talk with your doctor if you're breastfeeding. Run your exact medications through the search tool on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cholesstrinol HPe 150 mg, straight from the product label.

Brand OptiChoice
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 216983
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cholesstrinol HPe 150 mg by OptiChoice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Cholesstrinol HPe150 mg--
PMF-source Citrus Flavones0 NP--
ErioSource Eriocitrin0 NP--
TocoSource Palm Tocotrienols0 NP--

Other ingredients: Rice powder, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clinically proven award winning high potency heart health formula

Ultimate 2x potency

Formula

Cholesstrinol HPe (2x high potency) is a patented, clinically proven combination of PMF-source Citrus Flavones, TocoSource Palm Tocotrienols and ErioSource Eriocitrin.

Formulation

Cholesstrinol HPe synergistically supports the body's natural promotion of healthy cholesterol and triglyceride levels by utilizing multiple mechanisms and bio-pathways. Additionally Cholesstrinol HPe provides powerful antioxidant effects while promoting the body's healthy inflammatory response.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take one capsules per day or as directed by your health care professional or pharmacist.

Storage

Storage: Keep tightly closed in a cool, dry place in the original container. Do not expose to excessive heat.

Precautions

Keep out of the reach of children.

Caution: Do not use if seal is broken.

As with all dietary supplements, please consult a medical professional before using if you are pregnant, lactating, or have an existing medical condition.

Brand IP Statement(s)

Cholesstrinol HPe is a trademark of SOURCEONE GLOBAL PARTNERS.

Optichoice, TocoSource and PMF-source are registered trademarks of SOURCEONE GLOBAL PARTNERS.

Vcaps is a registered trademark of Capsugel. For more information, please visit www.source-1-global.com.

Seals/Symbols

Vcaps

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cholesstrinol HPe 150 mg by OptiChoice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cholesstrinol HPe 150 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cholesstrinol HPe 150 mg by OptiChoice

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cholesstrinol HPe

150 mg per serving

Other (inactive) ingredients: Rice powder, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cholesstrinol HPe 150 mg by OptiChoice Drug Interactions

Want to check YOUR meds against Cholesstrinol HPe 150 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

TocoSource Palm Tocotrienols 122

Individual Drug Interactions

The ingredients in Cholesstrinol HPe 150 mg interact with 122 drugs. Click any drug to see the details.

1 of the 3 ingredients in Cholesstrinol HPe 150 mg interact with drugs. Each result below shows which ingredient is responsible. TocoSource Palm Tocotrienols

Each ingredient & the kinds of drugs it affects

For each ingredient in Cholesstrinol HPe 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

TocoSource Palm Tocotrienols1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
TocoSource Palm Tocotrienols full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cholesstrinol HPe 150 mg, from the product label.

OptiChoice

See all OptiChoice products
Name
OptiChoice The Natural Choice for Optimal Health
Street Address
445 E. Illinois ST.
City
Chicago
State
IL
ZipCode
60611
Phone Number
1-800-755-4996
Pharmacist Counseling Corner

Cholesstrinol HPe 150 mg by OptiChoice: Common Questions

Does Cholesstrinol HPe 150 mg by OptiChoice interact with any medications?
Yes. Based on its ingredients, Cholesstrinol HPe 150 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cholesstrinol HPe 150 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually lower cholesterol?
The tocotrienol in this product is rated possibly ineffective for high cholesterol based on the evidence we hold. If lowering cholesterol is your goal, this may not be the right choice.
Can I take this if I'm pregnant?
The safety data advises against it — there isn't enough information to know it's safe during pregnancy. Talk with your doctor before taking it.
What's tocotrienol, and why is it in here?
Tocotrienols are a form of vitamin E extracted from palm oil. The evidence suggests it may help with blood sugar control, which is why it's included in this product.
Are there any side effects I should know about?
When taken by mouth, tocotrienols haven't caused any reported side effects in clinical trials and appear well tolerated overall.
What are those other two ingredients in this product?
PMF-source Citrus Flavones and ErioSource Eriocitrin are plant compounds from citrus. We don't hold interaction data for either of them, so we can't check how they interact with medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cholesstrinol HPe 150 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cholesstrinol HPe 150 mg label
Go deeper

The Full Monographs Behind Cholesstrinol HPe 150 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph →
Sources

Sources & How We Checked

Cholesstrinol HPe 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tocotrienols 4 references
  1. Mensink RP, van Houwelingen AC, Kromhout D, Hornstra G. A vitamin E concentrate rich in tocotrienols had no effect on serum lipids, lipoproteins, or platelet function in men with mildly elevated serum lipid concentrations. Am J Clin Nutr 1999;69:213-9. PubMed
  2. Baumann LS, Spencer JS. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatol Surg 1999;25:311-5. PubMed
  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
  4. Slivka A, Rink C, Paoletto D, Sen CK. Platelet function in stroke/transient ischemic attack patients treated with tocotrienol. FASEB J. 2020;34(9):11838-11843. PubMed

See these in context on the Tocotrienols monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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