AllerGzyme Ingredients & Drug Interactions
What is this page for?
First and foremost: checking AllerGzyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
AllerGzyme is a dietary supplement by Designs for Health with 2 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Protease and Peptidase. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against AllerGzyme by Designs for Health
Ask about any prescription or over-the-counter medication and we check it for interactions with AllerGzyme by Designs for Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of AllerGzyme by Designs for Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
AllerGzyme has 5 active ingredients, all of them proteolytic enzymes — proteins that break down other proteins in your digestive system. The main ones are protease (listed multiple times) and peptidase.
These are also bundled into the branded enzyme blends BioCore(R) Pro and BioCore(R) Edge. The capsule also contains vegetable cellulose, rice bran, and water as inactive ingredients.
Does it work?
Couldn't assess
We don't have effectiveness ratings on file for the enzymes in this product, so the evidence for what it's designed to do isn't established in our data.
How safe is it?
Well-documented data
Protease is generally well tolerated for most adults, though some people report digestive upset or allergic reactions. In rare cases, people exposed to protease in occupational settings (like laundry facilities) have developed allergic rhinitis or asthma symptoms.
There isn't enough safety data to recommend this product during pregnancy — it's best avoided unless your doctor prescribes it. During breastfeeding, there's little safety data, so talk with your doctor or pharmacist before using it.
We couldn't find safety information for peptidase on file, so ask your pharmacist if you have concerns about that ingredient specifically.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Use the search tool on this page to verify your exact medications, especially since we have no data on peptidase.
The bottom line
Scorecard at a glancePartially disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is an enzyme supplement with no documented drug interactions in our data. If you're pregnant or breastfeeding, check with your pharmacist or doctor first.
And before you start, run your medications through the checker on this page — we couldn't verify one of the ingredients against your drug list.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about AllerGzyme, straight from the product label.
| Brand | Designs for Health |
|---|---|
| Barcode (UPC) | 879452001459 |
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2013 |
| DSLD ID | 22330 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for AllerGzyme by Designs for Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protease | 0 NP | -- |
| Peptidase | 0 NP | -- |
| Protease | 21250 HUT | -- |
| Protease | 4000 PC | -- |
| Protease | 50 SAPU | -- |
| BioCore(R) Pro | 50 mg | -- |
| BioCore(R) Edge | 100 mg | -- |
| Protease and Peptidase | 30000 HUT | -- |
Other ingredients: Vegetable Cellulose, Rice Bran, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BioCore(R) is a registered trademark of National Enzyme Company.
AllerGzyme(TM) is a digestive aid for those with gluten and other food protein intolerances.
Formulation
Does not contain gluten.
General
AGZ090
FDA Statement of Identity
Dietary Supplement
General Statements
For Professional Use Only
Manufactured in an NSF GMP Registered Facility
Notice: Color, size or shape may appear different between lots.
Suggested/Recommended/Usage/Directions
Recommended Use: As a dietary supplement, take one capsule with each protein-containing meal per day, or as directed by your health care practitioner.
Seals/Symbols
Guaranteed GMP COMPLIANT Products
Storage
STORE IN A COOL, DRY PLACE.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Formula
AllerGzyme(TM) is a digestive aid for those with gluten and other food protein intolerances.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
AllerGzyme by Designs for Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in AllerGzyme by Designs for Health
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
BioCore(R) Pro
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
BioCore(R) Pro monograph & interactionsBioCore(R) Edge
Other (inactive) ingredients: Vegetable Cellulose, Rice Bran, Water. These complete the product’s ingredient list but are not active constituents.
AllerGzyme by Designs for Health Drug Interactions
HelloPharmacist Interaction Report
AllerGzyme by Designs for Health contains enzymes that break down proteins.
No interactions are documented in our data for the ingredients we were able to check.
Read the full breakdown — every affected drug type, severity by severity
However, we couldn't verify interaction data for peptidase, one of the active ingredients in this product. We hold no monograph for it, so if you take any prescription medications, run them through the checker below — it's the safest way to know whether adding this product affects how your drugs work.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against AllerGzyme?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in AllerGzyme interact with 2 drugs. Click any drug to see the details.
1 of the 2 ingredients in AllerGzyme interact with drugs. Each result below shows which ingredient is responsible. Protease and Peptidase
WarfarinWarfarin
How Warfarin interacts with AllerGzyme — through 1 ingredient. Tap an ingredient for the detail:
Protease And PeptidaseWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Protease And Peptidase + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with AllerGzyme — through 1 ingredient. Tap an ingredient for the detail:
Protease And PeptidaseWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Protease And Peptidase + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in AllerGzyme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Protease and Peptidase
Warfarin (Coumadin)
Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.
Brand information
Manufacturer and brand details for AllerGzyme, from the product label.
Designs for Health
See all Designs for Health products- Name
- Designs for Health, Inc.
- Street Address
- 980 South Street
- City
- Suffield
- State
- CT
- ZipCode
- 06078
- Web Address
- www.designsforhealth.com
AllerGzyme by Designs for Health: Common Questions
Does AllerGzyme by Designs for Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Is it safe to use while breastfeeding?
What do these enzymes actually do?
Could this cause side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if AllerGzyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind AllerGzyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographPapain
Interacts with 2 drugsPapain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...
Read the full Papain monograph →Sources & How We Checked
AllerGzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Papain 11 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
- Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
- Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
- Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
- Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
- Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
- Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
- Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
- Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
- Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC