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Dietary supplement

Angelica Arc. Ingredients & Drug Interactions

by Wise Woman Herbals

Angelica Arc. label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Angelica Arc. against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Angelica Arc. is a dietary supplement by Wise Woman Herbals with 1 active ingredient. Its ingredients are commonly taken for general wellness and longevity, antioxidant support, heart and cholesterol health.Based on those ingredients, 186 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Angelica. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Angelica Arc. by Wise Woman Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Angelica Arc. by Wise Woman Herbals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Angelica Arc. by Wise Woman Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (3 mL) without saying how much of each component you get.

Angelica Arc. is a one-ingredient liquid supplement containing angelica (ashitaba) in a proprietary blend. The product also contains alcohol and spring water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ashitaba product and its label doesn't state a use — see Ashitaba's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient reliable evidence to rate angelica for alcohol-related liver disease. That means research hasn't yet established whether it works for that purpose — not that it doesn't work, just that we don't have the evidence to say either way.

The evidence, ingredient by ingredient Ashitaba

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Angelica is likely safe when used as a food, but safety of concentrated supplements hasn't been well studied. The safety data advises against using concentrated angelica supplements during pregnancy and while breastfeeding because there isn't enough information to know it's safe.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your pharmacist or doctor before starting this product.

Side effects, ingredient by ingredient Ashitaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ashitaba.
  • The most serious interaction on file is rated Moderate.
  • For scale: 186 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Angelica Arc., double-check any prescription medications you're on that are broken down by your liver's CYP1A2 pathway — this includes certain antidepressants, heart medications, and some pain relievers. If you're not sure whether your drug is affected, run it through the interaction checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Angelica Arc. may appeal to someone looking for herbal liver support, but the evidence for its effectiveness isn't established in our data. The bigger concern is its interaction with medications your liver processes.

If you take any prescription drugs, check them against this product first — and if you're pregnant or breastfeeding, get personalized advice from your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Angelica Arc., straight from the product label.

Brand Wise Woman Herbals
Barcode (UPC) 748840020320
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284769
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Angelica Arc. by Wise Woman Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
60 Drop(s)
Servings per container
20
UPC/BARCODE
748840020320
IngredientAmount% DV
Proprietary Blend3 mL--
Angelica0 NP--

Other ingredients: Alcohol, spring Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake well. Add 20-60 drops of water, 2-4 times per day.

Formulation

The presence of particulate matter in this product is normal.

Organic alcohol: 60-70%

Botanical formula

Precautions

Caution: May cause problems if used in conjunction with blood thinners. Not recommended during pregnancy.

Keep out of the reach of children.

Formula

Organic alcohol: 60-70% Herb strength ratio: 1:1.5

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry area away from direct sunlight with the lid tightly sealed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Angelica Arc. by Wise Woman Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Angelica Arc. label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Angelica Arc. by Wise Woman Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Servings per container20 Amounts shown are per serving.

Proprietary Blend

3 mL per serving

Other (inactive) ingredients: Alcohol, Spring Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Angelica Arc. by Wise Woman Herbals Drug Interactions

Want to check YOUR meds against Angelica Arc.?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
186Drugs
186 Moderate

Ingredients driving the most interactions

Angelica 186

Individual Drug Interactions

The ingredients in Angelica Arc. interact with 186 drugs. Click any drug to see the details.

1 of the 1 ingredient in Angelica Arc. interact with drugs. Each result below shows which ingredient is responsible. Angelica

Each ingredient & the kinds of drugs it affects

For each ingredient in Angelica Arc. with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Angelica1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.

Likelihood Possible Evidence D
Angelica full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Angelica Arc., from the product label.

Wise Woman Herbals

See all Wise Woman Herbals products
Name
Wise Woman Herbals
City
Creswell
State
OR
ZipCode
97426
Phone Number
541.895.5152
Web Address
wisewomanherbals.com
Pharmacist Counseling Corner

Angelica Arc. by Wise Woman Herbals: Common Questions

Does Angelica Arc. by Wise Woman Herbals interact with any medications?
Yes. Based on its ingredients, Angelica Arc. has a known interaction with 186 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Angelica Arc. contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is angelica safe during pregnancy or while breastfeeding?
The safety data advises against concentrated angelica supplements during pregnancy and breastfeeding because there isn't enough information. If you're pregnant, planning to become pregnant, or nursing, talk with your pharmacist or doctor for personalized advice before you start.
Does this product actually work for liver health?
The evidence we hold shows insufficient reliable evidence to rate angelica for alcohol-related liver disease. That means we don't have enough research data yet to say whether it works for that purpose.
What is ashitaba, and how is it different from regular angelica?
Ashitaba (also called angelica) is the plant species used in this supplement. In our data, it's the same ingredient — the name just reflects the scientific or regional name for the plant.
Does this liquid contain alcohol?
Yes — the product includes alcohol and spring water as inactive ingredients. If you need to avoid alcohol, this may not be the right choice for you.
Can I take this with my heart or antidepressant medication?
Angelica may slow how your liver clears certain heart medications and antidepressants (CYP1A2 substrates), which could raise their levels and increase side effects. Before you start, check your exact medications with the interaction tool on this page or ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Angelica Arc. is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Angelica Arc. label
Go deeper

The Full Monographs Behind Angelica Arc.’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashitaba

Interacts with 186 drugs

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...

Read the full Ashitaba monograph →
Sources

Sources & How We Checked

Angelica Arc.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashitaba 2 references
  1. Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
  2. Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.

See these in context on the Ashitaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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