Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Anti-Gas Enzyme Ingredients & Drug Interactions

by Swanson

Anti-Gas Enzyme label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Anti-Gas Enzyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Anti-Gas Enzyme is a dietary supplement by Swanson with 5 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Protease 3.0. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Anti-Gas Enzyme by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Anti-Gas Enzyme by Swanson — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Anti-Gas Enzyme by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (40 mg) without saying how much of each component you get.

This product contains five active ingredients — all enzymes meant to help break down food in your digestive tract. Lipase breaks down fats, Amylase works on carbohydrates, Protease 3.0 tackles proteins, and Cellulase and Hemicellulase help with fiber and plant material.

They're packaged together in a proprietary blend to target multiple nutrients at once. The inactive ingredients are Microcrystalline Cellulose, Hypromellose, and Medium Chain Triglyceride — these are the capsule and filler materials that hold everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: helps with mild occasional gas and bloating.
  • We looked for evidence on: Dyspepsia, Flatulence, Bloating, Digestive discomfort.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is sparse. For Lipase, we don't have enough reliable data to say whether it works for indigestion (dyspepsia) or inflammatory bowel disease (IBD) — the rating is insufficient evidence.

The same limited-evidence picture applies to the other enzymes in this blend. Enzyme supplements remain popular for digestive support, but solid proof of benefit isn't established in our data.

The evidence, ingredient by ingredient Lipase Papain

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase is generally well tolerated when taken as a supplement, though people with serious digestive conditions should use it only under a doctor's guidance. There's little safety data on supplemental lipase in pregnancy or while breastfeeding, so check with your healthcare provider first if either applies to you.

We hold no safety information on the other four active enzymes. Adverse effects haven't been reported in adults taking lipase supplements in the usual way, though a full safety review hasn't been done.

Premature infants given a special recombinant form of lipase in formula or breast milk have shown rare serious gastrointestinal effects — this doesn't apply to oral capsules in adults, but it's worth knowing.

Side effects, ingredient by ingredient Lipase Papain

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Papain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

No interactions are documented in our data for the enzymes we could check. Before you start, verify your medications using the tool on this page — especially if you take anything regularly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward enzyme blend for people who want digestive support. If you take prescription medications or have a serious digestive condition, check with your pharmacist or doctor first.

The evidence for benefit isn't strong, so see how you feel after a few weeks.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anti-Gas Enzyme, straight from the product label.

Brand Swanson
Barcode (UPC) 087614025278
Net contents 90 Veggie Cap(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 308466
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anti-Gas Enzyme by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
3 Veggie Capsule(s)
Servings per container
90
UPC/BARCODE
087614025278
IngredientAmount% DV
Lipase0 NP--
Cellulase0 NP--
Hemicellulase0 NP--
Proprietary Enzyme Blend40 mg--
Amylase0 NP--
Protease 3.00 NP--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helps with mild, occasional gas and bloating due to everyday foods Promotes digestive comfort

Digestive Health High Potency Blend

Brand IP Statement(s)

Swanson Science-Backed Quality Since 1969

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule 10-15 minutes prior to a meal containing gas-producing foods, such as cruciferous vegetables, beans and legumes. Take up to three veggie capsules prior to a meal, if needed.

Precautions

Warning: For adults only.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

May contain tree nuts (Coconut).

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Anti-Gas Enzyme by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Anti-Gas Enzyme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Anti-Gas Enzyme by Swanson

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

40 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

Anti-Gas Enzyme by Swanson Drug Interactions

Want to check YOUR meds against Anti-Gas Enzyme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Protease 3.0 2

Individual Drug Interactions

The ingredients in Anti-Gas Enzyme interact with 2 drugs. Click any drug to see the details.

1 of the 5 ingredients in Anti-Gas Enzyme interact with drugs. Each result below shows which ingredient is responsible. Protease 3.0

Each ingredient & the kinds of drugs it affects

For each ingredient in Anti-Gas Enzyme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Protease 3.01 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
Protease 3.0 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Anti-Gas Enzyme, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Anti-Gas Enzyme by Swanson: Common Questions

Does Anti-Gas Enzyme by Swanson interact with any medications?
Yes. Based on its ingredients, Anti-Gas Enzyme has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anti-Gas Enzyme contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lipase safe to take if I'm pregnant?
There isn't enough safety data to know either way. If you're pregnant or planning to be, talk with your doctor or pharmacist before starting this product — they can give you personalized advice.
Can I take this while breastfeeding?
Safety while breastfeeding hasn't been well studied for lipase. Check with your healthcare provider first to make sure it's right for you.
Are these enzymes supposed to help with gas and bloating?
That's the idea — enzymes like amylase and protease are meant to help your body break down food more completely. We don't have strong evidence they work for gas specifically, but many people use them for that purpose.
What's a proprietary enzyme blend?
It's the manufacturer's mix of enzymes — in this case, Cellulase and Hemicellulase are combined into one blend. The amounts of each aren't disclosed on the label, but they're listed as separate ingredients so we can check them.
Has anyone reported side effects from taking this?
No adverse effects have been reported in adults taking lipase supplements the usual way. A thorough safety study hasn't been done, so keep an eye out for anything unusual and tell your pharmacist if you notice anything.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Anti-Gas Enzyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anti-Gas Enzyme label
Go deeper

The Full Monographs Behind Anti-Gas Enzyme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

Papain

Interacts with 2 drugs

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...

Read the full Papain monograph →
Sources

Sources & How We Checked

Anti-Gas Enzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team