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Dietary supplement

Apple Cider Vinegar Gummies - 60 Gummies Ingredients & Drug Interactions

by WEEM

Gummy Category: Herbal/dietary Supplement
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Apple Cider Vinegar Gummies - 60 Gummies is a dietary supplement by WEEM with 5 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 1,073 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pomegranate powder, Beet, Apple Cider Vinegar powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Apple Cider Vinegar Gummies - 60 Gummies by WEEM

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This gummy contains five active ingredients: vitamin B12, pomegranate powder, beet, apple cider vinegar powder, and folic acid. Vitamin B12 supports nerve function and energy; pomegranate is a fruit antioxidant; beet is a root vegetable known for nitrates and pigments; apple cider vinegar powder is a fermented apple product; and folic acid is a B vitamin.

The remaining ingredients are gummy binders, sweeteners, and natural colors—pectin, sodium citrate, citric acid, carnauba wax, and glucose syrup, along with beta-carotene and purple carrot concentrate for color.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: detox weight loss digestion immune energy.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for this product's ingredients is mixed. Vitamin B12 is effective for B12 deficiency and likely effective for cyanide poisoning; it's possibly effective for canker sores and nerve pain.

Folic acid is effective for folate deficiency and likely effective for preventing neural tube birth defects; it's possibly effective for depression and cognitive impairment. Pomegranate is possibly effective for high blood pressure but possibly ineffective for high cholesterol and diabetes.

Beet is possibly effective for athletic performance and exercise-related muscle soreness but possibly ineffective for COPD. Apple cider vinegar powder lacks established evidence for any of the conditions we hold data on—acne, athletic performance, cognitive function, dental plaque, depression, and eczema are all rated insufficient evidence.

Overall, the strongest evidence here is for the B vitamins, not the apple cider vinegar or beet components.

The evidence, ingredient by ingredient Vitamin B12 Pomegranate Beet Apple Cider Vinegar Folic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In typical food and supplement doses, these ingredients are generally well tolerated. Vitamin B12 is very safe—excess is shed in urine and has no upper limit.

Pomegranate fruit and juice are safe in normal amounts but concentrated extracts lack safety data; mild gastrointestinal upset (diarrhea, gas) occurs in a small number of users at high doses. Beet is fine as a food but concentrated supplements lack safety data; expect harmless red or black stools.

Apple cider vinegar is safe in food amounts but large doses carry risk—long-term overuse has caused dangerously low potassium, high renin levels, and bone loss in rare cases. Folic acid is safe at recommended doses; at 15 mg daily or higher, some people report sleep changes, vivid dreams, irritability, and nausea.

Large folic acid doses can also worsen nerve damage in people already deficient in B12, so you shouldn't self-treat suspected anemia.

Side effects, ingredient by ingredient Vitamin B12 Pomegranate Beet Apple Cider Vinegar Folic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Beet, Pomegranate, Apple Cider Vinegar, Vitamin B12, Folic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,074 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use seizure medications (phenobarbital, phenytoin, or primidone)—folic acid can reverse their effects. Also flag blood pressure medications, warfarin, digoxin, diuretics, insulin, diabetes drugs, or any medication processed by your liver.

Your pharmacist can search your exact prescriptions using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take seizure medications, blood pressure drugs, warfarin, digoxin, diuretics, insulin, or drugs for diabetes or metabolized by your liver, run this product through our medication checker before starting—the interactions are real. If you're considering it mainly for apple cider vinegar's weight or digestive claims, the evidence doesn't support those uses yet.

Talk it over with your doctor or pharmacist first, especially if you're on any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2026.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apple Cider Vinegar Gummies - 60 Gummies, straight from the product label.

Brand WEEM
Barcode (UPC) 860004567707
Net contents 60 Gummies
Market status On market
Added to our catalog Jul 27, 2026
Product type Herbal/dietary Supplement
Supplement form Gummy
Dietary claims / uses Natural detox, Helps digestion, Weight loss support, Immune system support, Boosts energy, Heart health
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apple Cider Vinegar Gummies - 60 Gummies by WEEM, compiled by our pharmacy team from the manufacturer's label.

Supplement Facts

Daily Value (DV) Target Group(s):
N/A
Minimum serving Sizes:
2 Gummy
Maximum serving Sizes:
2 Gummy
Servings per container
30
UPC/BARCODE
860004567707
IngredientAmount% DV
Vitamin B122 mcg--
Pomegranate powder80 mcg--
Beet80 mcg--
Apple Cider Vinegar powder1000 mg--
Folic Acid400 mcg DFE--

Other ingredients: Pectin, Sodium Citrate, Citric Acid, Natural Apple Flavor, organic Carnauba wax, Purple Carrot Concentrate, Beta-Carotene, Sugar, Glucose Syrup, Glucose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested Use

Directions: Take 2 gummies daily. Chew each gummy thoroughly.

SUGGESTED USE: 2 GUMMIES PER DAY

Marketing

A POWERFUL NATURAL DETOX - Get all the great benefits of apple cider vinegar in a gummy that forms a powerful natural detox that flushes the body and digestive system strengthening the gut and helping to support overall health and wellness.

Premium Detox & Weight Supplement - Helps Digestion for Women and Men

PERFECTLY BALANCED COMPLEX BLEND OF NATURAL INGREDIENTS FOR IMMUNE SYSTEM SUPPORT & OTHER BENEFITS

Boosts Your Energy / Supports Healthy Weight Loss / Flushes Out Toxins / Improves Digestion

Other

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

*There statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Apple Cider Vinegar Gummies - 60 Gummies by WEEM label

The product's label imagery, on file with our pharmacy team. Tap to enlarge.

What’s inside

The Ingredients in Apple Cider Vinegar Gummies - 60 Gummies by WEEM

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy Dosage formGummy Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
2 mcg per serving Form: cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Pomegranate powder

Interacts with
922 drugs
80 mcg per serving Form: juice powder (fruit)

Pomegranate is a nutrient-rich fruit that is high in antioxidants and is widely enjoyed as food and juice. Early research suggests it may support hear...

Pomegranate powder monograph & interactions

Beet

Interacts with
861 drugs
80 mcg per serving Form: root powder

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet monograph & interactions

Apple Cider Vinegar powder

Interacts with
162 drugs
1000 mg per serving Form: powder (fruit)

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar powder monograph & interactions

Folic Acid

Interacts with
40 drugs
400 mcg DFE per serving Form: folic acid

Folic acid is the man-made form of vitamin B9 and is one of the most well-studied supplements, especially for preventing serious birth defects when ta...

Folic Acid monograph & interactions

Other (inactive) ingredients: Pectin, Sodium Citrate, Citric Acid, Natural Apple Flavor, Organic Carnauba wax, Purple Carrot Concentrate, Beta-Carotene, Sugar, Glucose Syrup, Glucose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apple Cider Vinegar Gummies - 60 Gummies by WEEM Drug Interactions

Want to check YOUR meds against Apple Cider Vinegar Gummies - 60 Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,073Drugs
924 Moderate 149 Minor

Ingredients driving the most interactions

Beet 861

Each ingredient & the kinds of drugs it affects

For each ingredient in Apple Cider Vinegar Gummies - 60 Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Pomegranate powder9 drug types · 922 drugs

Ace Inhibitors (Aceis)

Theoretically, taking pomegranate with ACEIs might increase the risk of adverse effects.
Pomegranate juice is thought to have ACE inhibitor-like effects.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Consuming pomegranate juice can modestly lower blood pressure.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
In vitro, pomegranate juice inhibits CYP2D6. However, the clinical significance of this potential interaction in humans is not known.

Likelihood Possible Evidence D
Rosuvastatin (Crestor)

Theoretically, taking pomegranate with rosuvastatin might increase the risk of adverse effects.
In one case, a patient taking rosuvastatin 5 mg every other day in combination with ezetimibe 10 mg daily developed rhabdomyolysis after drinking pomegranate juice 200 mL twice weekly for 3 weeks. This patient had a history of elevated creatine kinase levels while not receiving any statin treatment. This suggests a possible underlying myopathy and predisposition to rhabdomyolysis.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, pomegranate might increase warfarin levels and increase the risk of bleeding. Also, discontinuing regular consumption of pomegranate juice might decrease warfarin levels.
In one case report, a patient had a stable, therapeutic bleeding time, as measured by international normalized ratio (INR), while taking warfarin in combination with pomegranate juice 2-3 times per week. The patient became subtherapeutic within about 10 days after discontinuing pomegranate juice, which required a warfarin dose increase. In another case report, a patient with a stable INR for over one year presented with an INR of 14. The patient noted no changes to medications or diet but did report consuming around 3 liters of pomegranate juice over the previous week. The patient's INR stabilized upon moderation of pomegranate juice consumption. The mechanism of this potential interaction is unclear.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, taking pomegranate with carbamazepine might increase the risk of adverse effects, although research suggests this interaction is unlikely to be clinically significant.
Animal research shows that pomegranate juice may inhibit cytochrome P450 3A4 (CYP3A4) metabolism of carbamazepine and increase levels of carbamazepine by 1.5 times without prolonging the elimination half-life. This suggests that pomegranate juice inhibits intestinal CYP3A4, but might not inhibit hepatic CYP3A4. However, some human research suggests that pomegranate does not significantly inhibit CYP3A4 drug metabolism in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, pomegranate might increase levels of drugs metabolized by CYP2C9.
Some animal and in vitro research shows that pomegranate juice inhibits intestinal, but not hepatic, CYP2C9 isoenzyme activity. However, clinical research shows that neither pomegranate juice nor pomegranate extract have a significant effect on CYP2C9 activity in humans.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Pomegranate contains several polyphenols that have individually been shown to inhibit CYP3A4. However, there is contradictory evidence about the effect of whole pomegranate juice on CYP3A4 activity. In vitro, pomegranate juice significantly inhibits the CYP3A4 enzyme, with comparable inhibition to grapefruit juice. In an animal model, pomegranate juice inhibits CYP3A4 metabolism of carbamazepine and increases levels of carbamazepine by 1.5 times; however, in human volunteers, drinking a single glass of pomegranate juice 240 mL or taking 200 mL daily for 2 weeks does not significantly affect levels of the CYP3A4 substrate midazolam after oral or intravenous administration. Another study in healthy volunteers shows that consuming pomegranate juice 300 mL three times daily for three days also does not significantly affect levels of simvastatin, a CYP3A4 substrate This suggests that pomegranate is unlikely to significantly affect levels of CYP3A4 substrates in humans.

Likelihood Unlikely Evidence B
Tolbutamide (Orinase)

Theoretically, pomegranate might increase levels of tolbutamide, although research suggests this interaction is unlikely to be clinically significant.
Animal research shows that pomegranate juice inhibits the cytochrome P450 2C9 (CYP2C9) metabolism of tolbutamide. Pomegranate juice increased tolbutamide levels by 1.2 times without prolonging the elimination half-life. This suggests that pomegranate juice inhibits intestinal CYP2C9, but might not inhibit hepatic CYP2C9. Despite this evidence, clinical research shows that neither pomegranate juice nor pomegranate extract have a significant effect on CYP2C9 activity in humans. This interaction does not appear to be clinically significant in humans.

Likelihood Unlikely Evidence D

Beet3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D

Apple Cider Vinegar powder4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B

Folic Acid7 drug types · 40 drugs

5-Fluorouracil

Theoretically, high doses of folic acid might increase the toxicity of 5-fluorouracil.
Increases in gastrointestinal side effects of 5-fluorouracil, such as stomatitis and diarrhea, have been described in two clinical studies when leucovorin, a form of folic acid, was administered with 5-fluorouracil.

Likelihood Possible Evidence D
Capecitabine (Xeloda)

Use of high-dose folic acid might contribute to capecitabine toxicity.
Clinical research suggests that higher serum folate levels are associated with an increased risk for moderate or severe toxicity during capecitabine-based treatment for colorectal cancer. Additionally, in one case report, taking folic acid 15 mg daily might have contributed to increased toxicity, including severe diarrhea, vomiting, edema, hand-foot syndrome, and eventually death, in a patient prescribed capecitabine.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Folic acid might reduce the efficacy of methotrexate as a cancer treatment when given concurrently.
Methotrexate exerts its cytotoxic effects by preventing conversion of folic acid to the active form needed by cells. There is some evidence that folic acid supplements reduce the efficacy of methotrexate in the treatment of acute lymphoblastic leukemia, and theoretically they could reduce its efficacy in the treatment of other cancers. Advise cancer patients to consult their oncologist before using folic acid supplements. In patients treated with long-term, low-dose methotrexate for rheumatoid arthritis (RA) or psoriasis, folic acid supplements can reduce the incidence of side effects, without reducing efficacy.

Likelihood Probable Evidence B
Phenobarbital (Luminal)

Folic acid might have antagonistic effects on phenobarbital and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of phenobarbital and worsening seizure control. Monitor closely for increased seizure activity.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Folic acid might reduce serum levels of phenytoin in some patients.
Folic acid may be a cofactor in phenytoin metabolism. Folic acid, in doses of 1 mg daily or more, can reduce serum levels of phenytoin in some patients. Increases in seizure frequency have been reported. If folic acid supplements are added to established phenytoin therapy, monitor serum phenytoin levels closely. If phenytoin and folic acid are started at the same time and continued together, adverse changes in phenytoin pharmacokinetics are avoided. Note that phenytoin also reduces serum folate levels.

Likelihood Probable Evidence B
Primidone (Mysoline)

Folic acid might have antagonistic effects on primidone and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of primidone and worsening seizure control. Monitor closely for increased seizure activity. Note that primidone also reduces serum folate levels.

Likelihood Probable Evidence B
Pyrimethamine (Daraprim)

Folic acid might antagonize the effects of pyrimethamine.
Folic acid can antagonize the antiparasitic effects of pyrimethamine against toxoplasmosis and Pneumocystis carinii pneumonia. Folic acid doesn't antagonize the effects of pyrimethamine in the treatment of malaria, because malarial parasites cannot use exogenous folic acid. Use folinic acid as an alternative to folic acid when indicated.

Likelihood Probable Evidence D

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for Apple Cider Vinegar Gummies - 60 Gummies, from the product label.

Pharmacist Counseling Corner

Apple Cider Vinegar Gummies - 60 Gummies by WEEM: Common Questions

Does Apple Cider Vinegar Gummies - 60 Gummies by WEEM interact with any medications?
Yes. Based on its ingredients, Apple Cider Vinegar Gummies - 60 Gummies has a known interaction with 1,073 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apple Cider Vinegar Gummies - 60 Gummies contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data was compiled by the HelloPharmacist pharmacy team from the manufacturer's product label; the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this during pregnancy?
Vitamin B12 and folic acid are both safe at normal recommended doses during pregnancy—in fact, folic acid is recommended to help prevent birth defects. Pomegranate and beet in food amounts are likely fine, but safety data on concentrated supplements in pregnancy is limited. Apple cider vinegar safety in pregnancy isn't established. Talk with your doctor about whether this product fits your prenatal plan.
Can I take this if I'm breastfeeding?
Vitamin B12 and folic acid are both safe at recommended doses while breastfeeding. Pomegranate in food amounts is likely fine during lactation, but concentrated extract safety is unclear. Beet and apple cider vinegar safety data during breastfeeding isn't on file. Check with your pharmacist or doctor before adding it to your routine.
Does this actually work for weight loss or digestion?
We don't have evidence supporting apple cider vinegar for those uses. The facts on file rate its effectiveness for acne, cognitive function, dental plaque, depression, athletic performance, and eczema as insufficient—meaning the science isn't there yet. Don't count on this product for weight or digestive claims specifically.
What side effects should I watch for?
Most common: mild gastrointestinal upset (diarrhea, gas, nausea) from pomegranate at higher doses, and harmless red or black stools from beet. At very high doses of folic acid (15 mg daily), some people report sleep changes, vivid dreams, irritability, and confusion. If you feel dizzy, have unusual bruising, or notice severe weakness, stop and contact your doctor.
Can I take this with metformin?
There's a minor interaction: metformin can lower vitamin B12 levels over time, so prolonged use of both together might increase your risk of B12 deficiency. This doesn't mean you can't take them together, but your doctor should monitor your B12 levels if you're on metformin long-term and using supplements.
Is there anything else in this besides the main ingredients?
Yes—the gummy also contains pectin (a gelling agent), sodium citrate, citric acid, natural apple flavor, carnauba wax, sugar, glucose syrup, beta-carotene, and purple carrot concentrate for color. These are standard gummy fillers and aren't active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Apple Cider Vinegar Gummies - 60 Gummies label
Go deeper

The Full Monographs Behind Apple Cider Vinegar Gummies - 60 Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Apple Cider Vinegar Gummies - 60 Gummies's label data was compiled by the HelloPharmacist pharmacy team from the manufacturer's product label; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 138 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
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Pomegranate 27 references
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Beet 14 references
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Apple Cider Vinegar 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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