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Dietary supplement

Arabinogalactan Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Arabinogalactan is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arabinogalactan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Arabinogalactan by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: arabinogalactan, a fiber derived from larch trees. It works as a prebiotic, meaning it feeds beneficial bacteria in your gut.

The remaining ingredients are inactive — cellulose, water, and ascorbyl palmitate — which serve as the capsule material and a preservative.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Larch Arabinogalactan product and its label doesn't state a use — see Larch Arabinogalactan's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have sufficient reliable evidence to rate arabinogalactan for the common cold or high cholesterol. The studies so far haven't been robust enough to say whether it actually works for these purposes.

If you're considering it for one of these reasons, talk with your doctor about whether the evidence base is strong enough to fit your situation.

The evidence, ingredient by ingredient Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Arabinogalactan is generally well tolerated as a fiber. Some people experience bloating and flatulence, especially when they first start.

However, long-term safety data of high quality are limited, so caution is advised — talk with your doctor or pharmacist before using it, particularly if you have concerns or existing health conditions.

Side effects, ingredient by ingredient Larch Arabinogalactan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Larch Arabinogalactan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any immunosuppressant medication — such as cyclosporine, tacrolimus, mycophenolate, or others used after transplant or for autoimmune conditions — double-check with your doctor or pharmacist before taking this product. Arabinogalactan's immune-stimulating effect may interfere with these drugs' effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Arabinogalactan is a larch-derived prebiotic fiber that's generally well tolerated but has limited long-term safety evidence. The main concern is a potential interaction with immunosuppressant medications; if you take one, clear it with your doctor or pharmacist first.

The evidence for common cold or cholesterol benefits isn't strong enough to rate. Check in with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Arabinogalactan, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298003894
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 293889
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Arabinogalactan by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
766298003894
IngredientAmount% DV
Arabinogalactan500 mg--

Other ingredients: Cellulose, Water, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 3 times daily, between meals.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Formulation

Certification Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

Formula

Prebiotic fiber for immune support

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Arabinogalactan by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Arabinogalactan by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Arabinogalactan

Interacts with
121 drugs
500 mg per serving

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

Arabinogalactan monograph & interactions

Other (inactive) ingredients: Cellulose, Water, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Arabinogalactan by Pure Encapsulations Drug Interactions

Want to check YOUR meds against Arabinogalactan?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Arabinogalactan with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Arabinogalactan1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Arabinogalactan, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Arabinogalactan by Pure Encapsulations: Common Questions

Does Arabinogalactan by Pure Encapsulations interact with any medications?
Yes. Based on its ingredients, Arabinogalactan has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Arabinogalactan contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me avoid colds or lower my cholesterol?
The evidence isn't clear either way. We don't have enough reliable data to say whether arabinogalactan works for the common cold or high cholesterol. If you're hoping it will, talk with your doctor about whether it makes sense for you.
What are the side effects?
Most people tolerate it well. Some experience bloating and flatulence, especially when starting out. Long-term safety data are limited, so if you have ongoing health concerns, check with your doctor or pharmacist first.
Is it safe during pregnancy or breastfeeding?
We don't have enough safety data to say either way. Talk with your doctor or pharmacist for personalized advice, especially if you're pregnant or nursing.
What is arabinogalactan and what does it do?
It's a soluble fiber from larch trees. It acts as a prebiotic, meaning it feeds the good bacteria in your gut and may support digestive health.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Arabinogalactan is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Arabinogalactan label
Sources

Sources & How We Checked

Arabinogalactan's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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